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8 Mins
4 Sep 2018

Editor’s Pick: Chimeric Antigen Receptor-Engineered T Cell Therapy in Acute Myeloid Leukaemia

Acute myeloid leukaemia (AML) is a disease with a very poor outcome and remains an area of significant unmet need, necessitating novel therapeutic…
12 Mins
4 Sep 2018

Epstein–Barr Virus: A Biological Overview and Clinicopathological Changes of Two Epstein–Barr Virus-Related Lymphoproliferative Disorders in a World Health Organization (WHO) 2017 Report

Epstein–Barr virus (EBV) is one of the most important viral causes for the development of tumours. The global geographical epidemiology of EBV shows…
10 Mins
4 Sep 2018

A Game of Clones: The Complex Interplay of Aplastic Anaemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Haemoglobinuria

Although idiopathic aplastic anaemia (AA), myelodysplastic syndrome (MDS), and paroxysmal nocturnal haemoglobinuria (PNH) are all associated with…
6 Mins
2 Aug 2018

Planning Your Next Move in Philadelphia Chromosome Positive Leukaemias

The meeting was arranged as a series of conversations between experts, following a question and answer format with two speakers in each presentation…
9 Mins
2 Aug 2018

Editor's Pick: Allogeneic Haematopoietic Stem Cell Transplantation for Chronic Myeloid Leukaemia in the Era of Tyrosine Kinase Inhibitors

The introduction of tyrosine kinase inhibitors (TKI) has dramatically improved the prognosis of chronic myeloid leukaemia (CML) patients and, therefore…
10 Mins
2 Aug 2018

Therapeutic Options in Myelodysplastic Syndromes: Established and Emerging Therapies

Although hypomethylating agents (HMA) have revolutionised the treatment of myelodysplastic syndromes (MDS), a significant proportion of patients either…
11 Mins
2 Aug 2018

Making Rituximab Directly Cytotoxic for Substantial Improvement in Therapeutic Efficacy

The humanised anti-CD20 antibody (Ab) rituximab (RTX) has significantly improved the prognosis of B cell non-Hodgkin’s lymphomas (BNHL). However, major…
12 Mins
2 Aug 2018

Staging of Mycosis Fungoides and Sézary Syndrome: Time for an Update?

Mycosis fungoides is the most common variant of cutaneous T cell lymphoma and frequently presents as early-stage disease with skin patches and plaques with an indolent course, but patients experience significant morbidity from itch and disfigurement.
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