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8 Mins
8 Aug 2017

Editor’s Pick: The Role and Regulation of Quiescence in Acute Lymphoblastic Leukaemia

There are ˜3,000 children, as well an additional ˜7,000 adults, diagnosed with acute lymphoblastic leukaemia (ALL) each year in the USA.
7 Mins
8 Aug 2017

Thrombocytopenia: A Defect in Actin Dynamics?

The actin cytoskeleton plays many important roles in the lifecycle of platelets, from biogenesis from megakaryocytes, to activation and clearance from…
8 Mins
8 Aug 2017

The Role of Allograft in Acute Lymphoblastic Leukaemia, Including Alternate Donors

The management of acute lymphoblastic leukaemia (ALL) remains challenging.
12 Mins
8 Aug 2017

Double-Hit and Triple-Hit Lymphomas: New Perspectives for Their Classification

In 2016, an update on the classification of lymphoid neoplasm was published, and one of the modifications made focussed on B-cell lymphoma…
9 Mins
8 Aug 2017

Management of Adult Patients with Myelodysplastic Syndromes

The myelodysplastic syndromes form a heterogeneous group of clonal disorders with an increasing incidence in the elderly population and an emerging…
7 Mins
8 Aug 2017

Different Therapeutic Interventions and Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management

Sickle cell disease is a genetic disorder caused by sickle haemoglobin. In many forms of the disease, the red blood cells can change shape upon…
11 Mins
28 Jul 2017

The Pivotal Role of Proteasome Inhibition in Myeloma Treatment

Prof Munshi opened the presentation with a brief video highlighting the interaction of myeloma cells with the bone microenvironment…
11 Mins
1 Jun 2017

Extension of 2016 World Health Organization (WHO) Classification into a New Set of Clinical, Laboratory, Molecular, and Pathological Criteria for the Diagnosis of Myeloproliferative Neoplasms: From Dameshek to Vainchenker, Green, and Kralovics

Improved Clinical, Laboratory, Molecular, and Pathological (CLMP) 2017 criteria for myeloproliferative neoplasms (MPN) define the JAK2V617F trilinear…
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