Oncology

Onco-hospitalist programs may close key inpatient oncology care gaps in communication, collaboration, training, and cancer management.

Darolutamide showed less cognitive decline than enzalutamide in ARACOG results presented at ASCO 2026 for prostate cancer.

Head and neck cancer survival improved with TMC-I versus platinum chemotherapy in recurrent or metastatic disease.

Contrast-enhanced mammography showed good accuracy for assessing breast cancer response after neoadjuvant therapy in pooled data.

TALAPRO-3 data show talazoparib plus enzalutamide delayed progression in HRR-deficient metastatic castration-sensitive prostate cancer.

SUCCESSOR-2 data showed MeziKd prolonged progression-free survival in relapsed or refractory multiple myeloma at ASCO 2026.

Higher BMI was linked to a smaller sex-related difference in lung cancer survival across large European cohorts.

Metastatic NSCLC treatment reached fewer than half of older adults, despite major advances in systemic therapy.

Suzetrigine showed limited benefit for cancer-related bone pain in three patients with metastatic spinal disease.

Acupuncture therapies improved insomnia in patients with breast cancer, with combined mindfulness and acupressure ranking highest.

Immune checkpoint inhibitor therapy rarely caused persistent taste and smell dysfunction in long term survivors after cancer treatment.

Pregnancy-associated breast cancer research priorities reveal urgent biological, clinical, and psychosocial gaps in patient care.

Endometriosis is linked to ovarian cancer risk, but absolute lifetime risk remains low for most patients.

Bereaved families of young adults with cancer face greater grief and depression after end-of-life care.

Digital health technophobia varies widely among older patients with cancer, highlighting barriers to equitable digital cancer care.

Mindfulness-based stress reduction reduced chemotherapy-related nausea, vomiting, depression, and anxiety in patients with colorectal cancer.

Insular gliomas can be resected safely with mapping, with low morbidity across 500 surgical cases.

Palliative nursing interventions improved quality of life and reduced distress and symptom burden in older adults with cancer.

Time-of-day immunotherapy was associated with longer survival in patients receiving ICIs for advanced solid tumors.

Colon cancer treatment interval up to 49 days did not worsen cancer-free survival after curative surgery.

Salt intake was not genetically associated with gastric cancer risk in a two-sample Mendelian randomization analysis.

HPV vaccination has delivered major population-level reductions in infection, precancer, genital warts, and cervical cancer globally.

Prognostic dialogue in serious illness conversations may help patients balance hope with realistic expectations.

Preoperative breast cancer screening before chest masculinization surgery helped identify malignancy and improve surgical planning.

Acupuncture for chemotherapy-induced nausea and vomiting in breast cancer is now set for a broader comparative review.

Collaborative care helped a patient with opioid use disorder, advanced cancer, and housing instability complete treatment.

Smoking emerged as the strongest modifiable driver of esophageal squamous cell carcinoma in a large Johannesburg analysis.

Health care barriers were linked to lower cancer screening adherence across five major cancer types.

Cancer care in humanitarian settings remains fragmented, underprioritized, and urgently in need of cross-border policy solutions.

A case report explores whether mRNA COVID-19 vaccination may coincide with hematopoietic malignancy and possible mechanisms.

A new skin cancer risk stratification tool for solid organ transplant recipients shows strong international validation but inconsistent clinical adoption.

Next-generation sequencing use rose in advanced cancer, but access remained uneven across socioeconomic, racial, and insurance groups.

Risk-reducing surgery decisions were shaped most by ovarian cancer risk and menopausal symptoms in premenopausal women.

A mobile nutrition app improved dietary moderation and appetite loss outcomes in patients with cancer over 4 weeks.

CART cell therapy was linked to early hemostatic shifts that may help predict toxicity and bleeding risk.

Male breast cancer risk stratification may help identify which patients with luminal early disease benefit from chemotherapy.

Smart control of CAR T cells is advancing cancer immunotherapy by improving precision, safety, and adaptability.

Regional nodal irradiation in breast cancer showed low recurrence rates after nodal pCR, even when residual breast disease remained.

Psychological interventions for parents in pediatric palliative care improved short term mental health outcomes.

A nurse-led bladder management approach improved bladder volume reproducibility and reduced repeat imaging in prostate hypofractionated radiotherapy.

Sjögren’s disease linked to higher cancer risk in patients and close relatives in this cohort study.

Prostate biopsy under local anesthesia showed similar safety and detection outcomes, with better comfort trends for transperineal sampling.

Narrative-based palliative care reduced stress and improved quality of life in elderly terminal cancer patients and families.

Older adults with frailty often faced prolonged functional recovery and unmet care needs after major elective noncardiac surgery.

Sustainable breast cancer surgery was feasible in a pilot study, with high sentinel node detection rates preserved.

A new review has highlighted the gut microbiota as a potential systemic driver of liver metastasis in small cell lung cancer, shifting attention beyond tumor genetics alone to the gut liver axis.

Radiologic exposomics may help reveal how environmental exposures shape cancer biology through imaging biomarkers.

Exercise was associated with reduced cancer-related lymphedema risk, with meta-analysis showing a 29.0% relative reduction overall.

Cancer after cardiac surgery was tied to shorter long-term survival, even though in-hospital mortality remained low.

Transplant oncology is expanding liver transplantation for some cancers pairing downstaging therapy with strict selection criteria.

Cervical cancer screening disparities persist for African-immigrant women in the United States, highlighting barriers and care-gaps.

Nordic data link gastric bypass to rare, excluded stomach cancer, with risk rising after 10 years and diagnosis potentially delayed.

Prior cesarean delivery was linked to higher postmolar gestational trophoblastic neoplasia risk, without increased chemoresistance overall.

An AI-enabled vibrating capsule detected abnormal bowel tissue, by stiffness signals, hinting at colorectal cancer screening tests.

Rectal cancer surgery triggers perioperative microbiome shifts, with lower diversity plus increased Enterococcus and Streptococcus.

Robotic secondary cytoreductive surgery enabled rapid complete removal of three extrapelvic ovarian cancer recurrences in one case.

Polycyclic aromatic hydrocarbons in charcoal grill smoke reached extreme levels during pork belly cooking, researchers report.

New guidance details valuable approaches to analyze longitudinal patient-reported outcomes when many patients die during follow-up.

A qualitative review shows informal caregivers adapt feeding for children with cancer, often straining home routines and wellbeing.

Patient integration in oncology research can align therapies with needs by translating science into outcomes patients value, today.

Gut microbiota dysbiosis may shape colorectal cancer risk, with microbial signatures emerging as non-invasive screening biomarkers.

In lung cancer screening eight-session counseling with short-course nicotine replacement therapy delivered the best value per quit.

New nomograms improved survival prediction for acute erythroid leukemia, highlighting age and chemotherapy as factors nationwide.

Shoulder joint range of motion fell markedly 1 month after breast cancer surgery in Japan despite routine inpatient rehabilitation.

US cost-effectiveness analysis showed durvalumab in limited-stage small cell lung cancer improved survival but exceeded thresholds.

Six-year FROST trial data suggest cryoablation can durably control Stage I breast tumors, with low recurrence reported overall.

Synthetic lethality could counter cancer drug resistance by targeting tumor vulnerabilities that appear after treatment pressures.

Medicaid eligibility restrictions may contribute 1 million missed cancer screenings and advanced stage diagnoses, models suggest.

Neratinib markedly reduced vascular inflammation and atherosclerosis in mice by targeting ASK1, boosting effects with rosuvastatin.

Selenium modulated redox signaling in renal cell carcinoma cells, shifting reactive oxygen species and survivability trajectories.

Peripheral inflammatory cell counts were linked to depression prevalence in NHANES adults with a history of solid tumors.

Very high-risk prostate cancer predicted shorter survival than high-risk disease in nonmetastatic patients managed without surgery.

HPV self-collection education materials can boost screening confidence when language, visuals and inclusivity address key concerns.

Adult childhood cancer survivors demonstrated accelerated brain aging that tracked with cranial radiation and poorer neurocognition.

Cancer diagnosis was linked to cardiovascular disease mortality in UK Biobank, implicating inflammation and coagulation proteins.

Robotic surgery shortened hospital stay versus laparoscopy for obese patients with colorectal cancer, with comparable safety overall.

Neoadjuvant chemo-reirradiation alongside IOERT surgery produced manageable toxicity, and 75.7% two-year survival in patients with LRRC.

Host-related determinants of immunotherapy response in NSCLC hinge on body composition, metabolism, sex, and systemic inflammation.

An analysis confirms dual enrollment at private and safety-net hospitals is feasible for Phase I solid tumor trials, yielding higher diversity and similar patient survival rates.

Cancer clinical trials development in Latin America underperforms globally yet strengths could expand equitable evidence worldwide.

FT-IR microspectroscopy blood test detected a single circulating tumor cell in one patient with lung cancer, cytospun raw blood sample.

Patients with cancer given access to free acupuncture and massage treatments at a community center in East Harlem, New York, reported symptom relief and broad satisfaction with services in an evaluation study.

Male circumcision is associated with lower odds of women developing various cervical lesions, according to a systematic review and meta-analysis.

Insurance coverage influences quality of life outcomes for women with early-stage estrogen receptor positive breast cancer.

Real-world study shows GLP-1 use in breast cancer linked to clinical factors, social determinants, and ctDNA.

Early MRI predicts pathologic complete response and long-term outcomes in TNBC patients receiving pembrolizumab.

SABCS 2025 data show frequent biomarker changes in inflammatory breast cancer after neoadjuvant therapy.

New SABCS data reveal racial and socioeconomic disparities in metastatic HR+ breast cancer presentation and treatment timing.

For patients with head and neck cancer receiving radiation therapy, dysphagia can emerge early and persist as a chronic or late complication.

Pilot data suggest biosynthetic mesh breast reconstruction may offer acceptable outcomes for high-risk implant candidates.

PARP inhibitor maintenance therapy improved progression free survival in newly diagnosed advanced ovarian cancer but not survival.

Propensity matched data suggest robotic minimally invasive esophagectomy offers shorter hospital stay after neoadjuvant therapy compared with open approaches.

User-centered digital solutions may ease care pathways for plastic surgery patients with non-melanoma skin cancer.

New analysis of U.S. adults shows a marked gender gap in cancer-free life expectancy.

Age-based lung cancer screening could detect far more cases than current US risk-based eligibility criteria.

Treatment goals in older adults with acute myeloid leukemia now prioritize long-term survival with targeted regimens.

Perioperative corticosteroid use significantly reduced postoperative seroma formation in patients undergoing breast cancer surgery.

Prostate cancer screening remains inconsistent in U.S. primary care, even for men at clearly elevated risk.

Drug repurposing in oncology may accelerate immunotherapy by reusing familiar agents to reshape antitumor immunity.

Baseline quality of life at diagnosis was strongly associated with survival outcomes in patients with non-metastatic advanced pancreatic cancer.

Lung cancer clinical trial participation remains markedly low and varies significantly according to care setting and patient-level factors.

The COVID-19 pandemic was associated with distinct, long-term changes in cancer incidence between males and females.

Adults with colorectal cancer and colostomy reported significantly poorer health-related quality of life overall than peers.

Artificial neural networks stratified adults with head and neck cancer after chemoradiation using routine clinical data.

Immune checkpoint inhibitor therapy appears safe and effective for NSCLC in people living with HIV today.

Automating cancer registries promises efficiency gains but demands rigorous design privacy safeguards, and ongoing human oversight.

Higher BMI and thicker breast subcutaneous fat were linked to more malignant ultrasound characteristics in breast cancer.

Postdiagnosis statin use was associated with a modest but measurable reduction in breast cancer-related deaths among women with early-stage disease.

Persistent depression during adjuvant cancer therapy heightens treatment toxicity and significantly worsens overall QoL in early-stage cancer.

Prolonged sitting increases mortality risk in cancer survivors, but a healthy diet may significantly reduce that risk.

Transitions in care for patients with head and neck cancer remain a critical challenge, with new research revealing substantial evidence gaps.

Neurocognitive functioning declines across central nervous system cancers, shaped by tumor location and interacting treatment effects.

Cannabis laws were associated with lower opioid dispensing among commercially insured patients with cancer across U.S. states.

Melanoma quality of life differs during and after immunotherapy, with fatigue, skin issues, and sexual dysfunction.

The six-minute walking test offers an objective, low-cost assessment of postoperative recovery after pancreatic surgery.

High-risk women had limited awareness yet strong support for breast cancer polygenic risk scores in clinical risk assessment more.

Health-related quality of life remains significantly underreported in trials evaluating tyrosine kinase inhibitors and immune checkpoint inhibitors for early-stage non-small cell lung cancer.

A multimodal AI model has achieved significant advances in pan-cancer prognosis prediction by combining pathology images, genomics, and clinical data.

Survivors of childhood cancer face a heightened risk of developing severe valvular heart disease many years after completing treatment.

High-quality colposcopy training is vital to global efforts to eliminate cervical cancer, yet many healthcare systems face significant training gaps.