Urology

A combined ultrasound and CT model accurately predicts spontaneous stone passage in ureteral stones ≤10 mm, supporting safer conservative management decisions.

Robot-assisted radical prostatectomy was linked to significantly fewer short-term complications than open surgery in a large nationwide French cohort study.

A randomised trial shows transcutaneous tibial nerve stimulation reduces catheter-related bladder discomfort and improves early recovery after urologic surgery.

A nasal pressure technique significantly reduces pain during urinary catheterisation, offering a simple, non-pharmacological option for patient comfort in the ED.

A large NHANES analysis shows the red cell distribution width-to-albumin ratio is strongly associated with diabetic kidney disease risk in adults with diabetes.

New research suggests routine blood-based inflammation markers could help predict which men with enlarged prostates are likely to develop more severe symptoms.

Researchers report that yoga and general exercise deliver similar sleep outcomes for women managing urinary incontinence.

A new rapid, low-cost sequencing method delivers four-hour UTI diagnosis with high accuracy, detecting pathogens missed by routine tests and improving antibiotic decision-making.

Escalating antimicrobial resistance has been identified among urology inpatients in a new study from a Turkish tertiary centre, highlighting urgent stewardship needs.

A large Norwegian study shows that higher cardiorespiratory fitness is linked to a significantly lower long-term risk of urinary tract, bladder, and kidney cancers.

A new study highlights oxidative and neuroimmune changes in diabetic urinary incontinence, identifying 4-HNE as a key biomarker differentiating diabetic and non-diabetic cases.

An automated MRI decision aid (ProAI) improves detection of clinically significant prostate cancer, boosting accuracy and cutting radiology workload by 32%.

Sequential therapy shows poorer outcomes in upper tract urothelial carcinoma than bladder cancer, highlighting the need for more effective first-line treatments.

This study reports early outcomes of percutaneous kidney-sparing surgery for upper tract urothelial carcinoma, highlighting feasibility, recurrence rates, and follow-up needs.

Men receiving a penile prosthesis during prostate cancer surgery showed faster sexual recovery and better satisfaction than those treated years later.

Smoking and hysterectomy raise the risk of vaginal mesh erosion after POP surgery, according to a new systematic review and meta-analysis.

Certain cancer drugs, including CDK4/6, EGFR, VEGFR, and BRAF inhibitors, may raise the risk of progressive kidney dysfunction over two years.

Researchers identify ALYREF as a dual-role biomarker in bladder cancer, linked to aggressive disease yet improved immunotherapy response.

Study shows in-office transperineal prostate biopsy under local anaesthesia achieves high diagnostic accuracy without antibiotics.

Remimazolam offers a rapid onset and offset, cardiovascular stability, and organ-independent metabolism, making it especially suitable for older patients.

New research shows no clear link between diet, urinary pH, and recurrent UTIs in postmenopausal women. Learn more about this pilot study’s findings.

Researchers highlight early diagnosis and tumour type differences as key factors improving outcomes in testicular cancer.

IURES 2025 study supports transperineal prostate biopsy under local anaesthesia as a safe, effective diagnostic option.

Researchers at IURES 2025 report seminal vesicle sampling enhances diagnostic accuracy in transperineal prostate biopsies.

A Taiwanese study finds that upper tract urothelial carcinoma patients with a history of urinary stones face worse cancer-specific and disease-free survival after surgery.

Largest real-world study shows ADT + ARPI improves persistence and survival in metastatic hormone-sensitive prostate cancer.

A new study finds the DR-70 protein may help detect bladder cancer early and assess disease severity, offering a promising tool for patient care.

New study finds COVID-19 temporarily lowers sperm quality but recovery occurs within months. Learn how infection affects male fertility and recovery timelines.

After eight years, overall survival reached 78.9% in the combination group, compared with 69.5% among those receiving leuprolide alone.

The Mediterranean diet was particularly effective in improving sexual function, likely through enhanced vascular health and reduced systemic inflammation.

Findings revealed a clear correlation between the resected prostate weight and improved voiding function.

A recent clinical study found that TURP + TUIBN improves symptom scores and quality-of-life outcomes in patients with small-volume BPH.

US-RASP has emerged as a promising alternative that maintains sexual function while providing comparable outcomes in urinary symptom relief.

Foley catheter placement sometimes masked symptoms, particularly in female patients, further complicating timely detection.

Financial challenges, comorbidities, and drug interactions may limit access, while systemic inequities contribute to racial and ethnic disparities.

A major European survey finds that one in three people cannot identify cystitis as a bladder infection and that half remain unaware women are most at risk.

The subtrigonal inlay patch buccal mucosal graft (SIP-BMG) technique represents one such advancement.

Several risk factors increase the likelihood of postoperative urinary retention, including general or opioid-based anaesthesia and underlying benign prostatic hyperplasia.

The IMPLEMENT study explored why first-line treatment intensification remains underutilised and how clinicians’ behaviours, beliefs, and environments influence its uptake.

The present study explored whether enhancing sampling density in the TZ could improve cancer detection.

The study found that virtual modalities are effective for the remote delivery of behavioural urinary incontinence treatment for women veterans.

Results revealed that women using the mobile app bladder training programme reported marked improvements in their quality of life, measured through the ICIQ-LUTSqol scale.

Recurrence rates remain a concern, with up to one third of men experiencing disease return within two years.

Recent advances in three-dimensional (3D) culture technology have transformed the way researchers study bladder cancer.

One promising approach targets nectin-4, a cell adhesion molecule linked to poor outcomes in several cancers, including bladder cancer.

A predictive scoring system, incorporating both current and prior PSA values, revealed that patients with persistently elevated levels had a very low likelihood, under 10%, of their PSA decreasing below the threshold at follow-up.

Black men remain underrepresented in large screening trials, and screening rates declined across all groups after the 2012 US Preventive Services Task Force recommendations.

nalysis of the BLADDA urothelial cancer registry demonstrated that neoadjuvant chemotherapy was associated with reduced risk of invasive bladder cancer recurrence.

Results showed that bpMRI was noninferior to mpMRI for detecting clinically significant prostate cancer, defined as Gleason Grade Group 2 or higher.

By aligning pretreatment risk stratification more closely with AS eligibility, clinicians may feel more confident recommending surveillance, potentially reducing overtreatment.

This study investigated the microbiota of the distal ileum in patients undergoing iRARC without bowel preparation, using direct sampling during ICUD.

Overall, this research offers a practical web-based prediction tool that can support clinicians in tailoring patient follow-up and treatment.

Integrating routine hormone testing with pelvic floor ultrasound assessments could help identify high-risk women early.

The model was subsequently applied to 11,723 examinations in men who had no documented diagnosis of prostate cancer at the time of MRI, with an average patient age of 65.5 years.

With limited early-detection tools and only modest improvements in survival for advanced disease, clinicians urgently need reliable biomarkers to improve prognostication.

Discover a study showing lasting survival gains from treatment intensification in prostate cancer.

Specialists have described the approval as one of the most promising developments in decades for bladder cancer care.

Study finds timing of mirabegron dosing affects symptom relief and emotional outcomes in women with overactive bladder.

The present study assessed the efficacy of sub-anaesthetic esketamine for CRBD prevention in patients undergoing ureteroscopic lithotripsy.

The TALAPRO-2 study enrolled 805 patients from 200 centres across 26 countries, including North America, Europe, Israel, South America, South Africa, and the Asia–Pacific region.

Taken together, the findings suggest that targeted augmentation of cholinergic signalling may help bridge the gap between anatomical de-obstruction and functional recovery in BOO-mediated UAB.

While MRI performance does not appear to depend on testosterone and inter-reader agreement is high, open questions remain, including whether PSMA PET or genomic markers could further refine early detection.

The authors hypothesised that, in women with OAB, the additional sympathetic blockade produced by spinal anaessthesia would further unmask parasympathetic dominance.

Researchers have developed a PSA-based index incorporating MRI measurements of periprostatic fat that significantly improves the prediction of high-grade prostate cancer.

Find out more about the role of platelet-to-lymphocyte ratio in improving prostate cancer detection.

AI-assisted autocontouring safely outlines organs for prostate radiotherapy, study finds—though manual edits are still needed for the prostate itself.

A major study shows that nearly 1 in 6 men with biopsy Grade Group 1 prostate cancer are at higher risk than previously assumed, with outcomes comparable to intermediate-grade disease.

Despite aggressive interventions, the five-year survival rate remains below 50% for those with localised disease and plummets to less than 15% when metastasis occurs.

Further analysis identified HDAC3 and the glucocorticoid receptor (GR) as key players in drug resistance.

The researchers suggest that the success of true auriculotherapy may be due to its influence on bladder control mechanisms, possibly via the vagus nerve.

A growing body of research supports non-pharmacological treatments, particularly exercise, as effective in alleviating primary dysmenorrhea symptoms.

A new study offers an innovative solution inspired by nature: soft dendritic particles (SDPs) that mimic the adhesive properties of gecko feet.

The study concludes that paediatric patients with cannabis use disorder may be at higher risk of developing a range of lower urinary tract symptoms compared to their peers without CUD.

Learn how TCM plus PDE5 inhibitors boosts erectile function in diabetes patients, with no extra side effects reported.

Discover a study revealing how chemotherapy-induced tumour pyroptosis reprograms fibroblasts, promoting chemoresistance in bladder cancer.

A new clinical study has identified a potential link between abnormal urinalysis and somatisation symptoms in female patients with epigastric pain syndrome.

Pelvic floor muscle training (PFMT) is recommended as an initial treatment for post-RP SUI, but traditional home-based approaches often lack long-term adherence.

From an economic perspective, urodynamics added £463 in cost and yielded a modest 0.011 additional quality-adjusted life-years.

Discover a study that reveals a targetable CA125+ cell state in rare bladder cancer subtypes using single-cell RNA sequencing.

Learn how EGF and UMOD levels may predict diabetic kidney disease progression, offering new tools for clinical risk assessment.

Non-muscle invasive bladder cancer, representing roughly 75% of cases, remains confined to the bladder lining and submucosa, often recurring but rarely advancing.

Patients treated on the entire prostate or surgical bed had better DMFS compared to those treated only on the relapse site.

Results showed that US overestimated bladder volumes compared to CBCT, with an average deviation of 60.75 ml.

Profiling urine tumour DNA at baseline and after 3 months of treatment could identify whether patients with bacillus Calmette-Guérin-unresponsive non-muscle-invasive bladder cancer might not benefit from systemic immunotherapy.

These insights are particularly relevant in minimally invasive surgery, where precision and confidence are vital.

The GETSBI study is not only crucial for this specific patient group but also holds broader implications for research in rare, chronic conditions.

Preliminary outcomes indicated that AE may improve haemoglobin levels, possibly counteracting androgen deprivation therapy induced reductions.

The guidelines endorse adjuvant nivolumab for patients with pT3/4 and/or pN+ disease who are unsuitable for, or have declined, cisplatin-based chemotherapy.

Importantly, 30% mean reductions in prostate volume were sustained up to 18 months post-procedure.

Insomnia appeared in 61%, cognitive impairment and irritability in 38%, and more severe psychiatric issues such as psychosis and delirium were rarely considered.

Discover a recent study that found that smoking is associated with worse sexual function outcomes following radical prostatectomy.

Students using ChatGPT alone scored lower than those attending lectures suggesting that AI tools may not sufficiently support complex learning.

Discover a study where a checklist facilitated closed-loop management, ensuring continuity of care despite environmental changes.

Discover a study where researchers introduced a conceptual design for a toilet-mounted home device capable of non-invasively measuring urine flow, volume, and frequency.

This clinical trial evaluated the safety of stereotactic body radiotherapy to the prostate bed following radical prostatectomy.

The study analysed data from 1,757 urine samples collected as part of the Swiss Kidney Project on Genes in Hypertension (SKIPOGH).

Discover a study that found that 22% of patients who underwent radical cystectomy were upstaged at surgery, leading to a lower 12-month progression-free survival rate.

The proportion of radical prostatectomies ending in pGG1 fell from 32.4% in 2010 to just 7.8% by 2020

The investigation began with a comparison between 3,716 PCa patients from Johns Hopkins University, Baltimore, Maryland.

he analysis also highlighted that treatment intensification with enzalutamide benefited patients regardless of baseline PSA.

Gill described the event as a “historic moment in medicine,” potentially transforming treatment options for patients.

Discover a study that has demonstrated the potential of using AI to predict jaundice by analysing scleral images and urine colour.

Despite limitations, this review offers a foundational overview of the capabilities and challenges of next-generation robotic systems.

Researchers explored the effectiveness of combining biofeedback training with osteopathic techniques to improve outcomes in children with urinary incontinence.

The study aimed to assess the risk of IED following urologic procedures with or without antibiotic prophylaxis.

Findings suggest that both TPTNS and rTMS may have value in symptom management and quality-of-life improvement in MS patients with neurogenic OAB.

The analysis included patient-reported symptoms from treatment initiation to cycle 12 of pembrolizumab.

Early results support the theory that combining systemic and localised treatment in oligometastatic prostate cancer can improve tumour control.

Discover a recent study that has provided crucial new insights into the treatment of upper tract urothelial carcinoma.

Commensal bacteria from the gut, urinary tract, and prostate tissue may play an unexpected role in the progression of prostate cancer.

New data from PUrE RCT 1 reveals no difference in quality-of-life between patients treated with ESWL or FURS for ≤10 mm LPSs.

Hydrogel safer but less satisfying than mesh in long-term stress incontinence treatment, study finds.

This pioneering study provides valuable insights into dietary assessment techniques in older adults with sarcopenia.

In comparison with other established biomarkers, such as the free/total PSA ratio and PSA density, Stockholm3 outperformed these tests.

Volatile anaesthetics and propofol show no significant difference in intraoperative urine output, study suggests.

Pyramidal and threshold training boost endurance in cancer survivors, with threshold requiring less time.

The study demonstrated that the use of microultrasonography-guided biopsy could provide an alternative to MRI.

Discover how individualised treatment for febrile UTIs lowers antibiotic use and reduces adverse events in children.

Though urodynamics altered the diagnosis in 13% of women this did not translate to improved outcomes.

VEIL outperforms OIL in reducing complications and recovery time in penile cancer surgery, offering notable clinical benefits.

The study found that 74 of these participants would not have been identified through the UK’s current diagnostic pathway.

The findings revealed that total radiographic disappearance of metastases occurred in 15% of patients.

Transperineal prostate biopsies offer higher accuracy in repeat biopsy cases and reduced infection risks.

NeuroSAFE-guided prostate surgery significantly improves erectile function and urinary continence recovery compared to standard methods.

Oral oestrogen increases the risk of overactive bladder in women under 65.

A study reveals that proteinuria in young adults is linked to a significantly higher risk of sudden cardiac arrest.

A randomised pilot study investigated whether scheduled IV acetaminophen administration would offer longer-lasting relief than a single dose.

Recent research suggests that precision treatment may improve outcomes in prostate cancer treatment.

Discover how isodose MHFRT offers comparable cancer control to CFRT with fewer gastrointestinal side effects, improving patient outcomes.

Micro-ultrasound matches MRI in prostate cancer detection, offering faster, cheaper diagnosis.

TB vaccine boosts immunity in bladder cancer patients, all cancer-free after 5 years.

Waterjet surgery preserves ejaculation in 85% of patients with benign prostatic hyperplasia . Laser alternatives lag at 23%.

A new study suggests heated lidocaine gel combined with periprostatic nerve block reduces pain during prostate biopsy without increasing complications.

Smart t-shirt enables earlier discharge after urological cancer surgery, improving patient comfort and reducing hospital stays.

Notably, AI-driven models outperformed traditional clinical risk calculators like the EORTC and EAU models.

Index-based dietary patterns were not linked to PCa-specific mortality, though associations varied by race and ethnicity.

Processed foods and fast foods, which are high in unhealthy fats and low in fibre, were also found to exacerbate pelvic floor disorder symptoms.

Recent research comparing laparoscopic and open radical prostatectomy outcomes shows that radical prostatectomy leads to shorter hospital stays.

The primary treatment for intermediate and high-risk NMIBC includes transurethral resection of the bladder tumour.

New research shows that at-home prostate cancer tests are producing inconsistent and inaccurate results.

A study of 666 localised prostate tumours identified 223 driver regions, many influenced by structural variations undetectable via targeted sequencing.

Lower oestradiol and FSH levels are linked to renal cell carcinoma, highlighting potential hormonal influences on tumour progression.

The results suggest trends towards overall survival and progression-free survival improvements with pembrolizumab in combination with platinum-based chemotherapy.

Danish study finds anticholinergic bladder drugs linked to dementia risk, but not when compared to mirabegron.

The combination of durvalumab and tremelimumab with concurrent radiotherapy is a feasible and safe treatment strategy.

A recent study comparing the efficacy of mirabegron and solifenacin in children with overactive bladder revealed that both treatments were equally effective.

The results showed that the music group experienced significantly less pain, with a median VAS score of 3.6 compared to 5.4.

These findings suggest that strategies targeting visceral fat reduction may aid in overactive bladder management.

Ultimately, these findings highlight the potential for urinary DNA methylation testing to improve early detection and diagnosis of bladder cancer.

Blocking GDF-15 with visugromab enhances immune checkpoint therapy, offering new hope for resistant advanced cancers.

Researchers aimed to establish a plasma ctDNA sequencing assay and evaluate its effectiveness in assessing tumour genetics and treatment response.

By offering a non-invasive, highly specific approach, MyProstateScore 2.0 enhances clinical decision-making while reducing patient burden.