Allergy & Immunology

Researchers report that combining allergen-specific mRNA therapy with mTOR inhibition enhanced immune tolerance and reduced allergic inflammation in a preclinical asthma model.

A nationwide online food allergy training programme significantly improved school staff knowledge and confidence in managing allergic emergencies.

Early, high-dose, and prolonged steroid use was associated with poorer survival in patients receiving immune checkpoint inhibitors.

Preventive house dust mite SLIT induced blocking antibodies and reduced allergic immune responses in sensitised preschool children.

Persistent Alternaria sensitisation from childhood was associated with higher risks of asthma and rhinitis in adulthood.

Italian multicentre study finds venom immunotherapy is safe in pregnancy, with no increased risk of miscarriage or preterm birth.

Metabolomic profiling identified distinct biological asthma subgroups despite similar symptom control and exacerbation histories.

Slow up-dosing peanut oral immunotherapy helped most preschool children achieve sustained unresponsiveness with few severe reactions.