News

GLP-1RA use lowered cardiovascular, kidney, and mortality risks in patients with lupus and diabetes

Discover a study showing how HCV eradication with antivirals during immunotherapy improves survival, liver function, and treatment outcomes in advanced hepatocellular carcinoma.

Routine blood tests can now predict spinal cord injury outcomes and severity earlier, powering better emergency care for patients.

These findings strengthen evidence supporting plant-based dietary strategies for gout prevention, highlighting lignans and specific whole grains as protective components.

Adaptive brain stimulation proves safe and effective for Parkinson, reducing side effects while maintaining long-term symptom control.

New study reveals how iron levels influence FLASH radiotherapy’s dual effect of tumour control and normal tissue protection.

Researchers identify LRP8 as the essential receptor for tick-borne encephalitis virus in brain cells, offering new targets for antiviral therapy.

A large UK Biobank study has found that exposure to hard water is associated with reduced prevalence of Crohn’s disease and ulcerative colitis.

Discover a study showing how neoadjuvant immunotherapy with tiragolumab and atezolizumab improves response rates and safety in high-risk Stage III melanoma.

New ERS 2025 research links paternal smoking in puberty with accelerated biological ageing in offspring, reinforcing evidence of intergenerational tobacco harms.

Recent advances in three-dimensional (3D) culture technology have transformed the way researchers study bladder cancer.

A multicentre study presented at ERS Congress 2025 found that remote monitoring reduced hospital visits and improved asthma control in children, strengthening the case for digital health in routine asthma care.

New research shows that paternal smoke exposure before puberty is associated with reduced lung function trajectories in offspring, increasing long-term respiratory risk.

Discover how a recent cohort study links medical imaging radiation to increased childhood haematologic cancer risk.

Large-scale observational and genetic analyses reveal that alcohol consumption is associated with higher dementia risk. Genetic evidence contradicts protective effects of light drinking.

A longitudinal study of 188 cervical cancer patients undergoing brachytherapy revealed that multidimensional fatigue slightly increased during treatment, peaking after five sessions, then significantly decreased one month post-treatment.

Learn how low-dose ATG may preserve β-cell function in young people with recent-onset Type 1 diabetes.

The study examined how attendance at the first invited mammography screening influenced future screening behaviour, tumour characteristics, and breast cancer mortality.

A UK Biobank analysis presented at ERS Congress 2025 found that higher fruit intake reduced the negative effects of fine particulate air pollution on lung function, particularly in women.

Recent research has investigated whether low-molecular-weight fucoidan, a compound derived from brown seaweed, could enhance the efficacy of TACE.

The CHILD study analysis found that early exposure to higher levels of dog allergen reduced asthma risk and improved lung function at age 5, with effects modified by genetic background.

A new study finds that surgery for ovarian endometriomas before IVF or ICSI does not improve live birth rates, supporting a more tailored fertility approach.

A Mali cohort study shows preterm birth elevates malaria infection risk in children, particularly in multigravid mothers without pregnancy malaria, suggesting targeted prevention and vaccination strategies.

A study reveals that TGF-β1 drives maladaptive bone marrow endothelial cell repair, impairing haematopoietic support. Blocking TGF-β1 with luspatercept restored cell function and improved blood cell recovery in post-transplant patients.

In a randomised, placebo-controlled trial, researchers evaluated VC-H1, a hibiscus enzyme extract, as an oral plant-based collagen alternative for photoaged skin.

Robotic-assisted bronchoscopy with cone-beam CT achieved far higher diagnostic yields than conventional bronchoscopy, particularly for small and ground-glass lesions, offering a powerful new tool for early lung cancer diagnosis.

One promising approach targets nectin-4, a cell adhesion molecule linked to poor outcomes in several cancers, including bladder cancer.

Research in adolescents shows that screen use, physical activity, and pre-bedtime food have little impact on youth sleep outcomes, though screens delay sleep onset. Guidelines for bedtime behaviors may need updating.

Explore how supplementing DBT with molecular breast imaging significantly improves invasive breast cancer detection in women with dense breasts.

A Phase I/II trial of AMT-130 gene therapy slowed Huntington’s disease progression by 75% over 36 months, showing biomarker and functional benefits.

A new study reports that the adjuvanted RSVPreF3 OA vaccine generates stronger immune responses than RSVpreF in immunocompromised adults.

Understand how GLP-1 receptor agonists may reduce fracture risk and improve bone density in Type 2 diabetes

Lateral flow Enhanced by Optical imaging combines the proven lateral flow assay platform with advanced smartphone-based image analysis.

A new randomised controlled trial has investigated the impact of dietary fibre supplementation on patients with T2DM and MASLD.

Dementia prevention must start in childhood, with new evidence linking lifelong social adversity to brain decline and disease risk.

A new study reveals circulating tumour DNA correlates with tumour volume in metastatic pancreatic cancer, particularly with liver metastases.

A phase 2 trial in Gabon showed that the PfSPZ malaria vaccine is safe in children aged 1–12 years but failed to prevent Plasmodium falciparum infection.

Discover a study revealing how insomnia raises the risk of GERD and IBS, with genetic evidence linking poor sleep to gastrointestinal health.

The study demonstrated that [99mTc]Tc-Tilmanocept could detect secondary lesions in patients with melanoma undergoing ICI treatment.

Survey finds supplement labels mislead consumers into thinking products prevent disease, prompting calls to tighten regulatory standards.

A predictive scoring system, incorporating both current and prior PSA values, revealed that patients with persistently elevated levels had a very low likelihood, under 10%, of their PSA decreasing below the threshold at follow-up.

PET-MRE significantly reduced SUVMax and inflammation markers in small bowel Crohn’s disease.

Scientists develop a blood test that measures aging across 11 body systems, offering more precise insights into health risks.

Innovative AI tool MARLIN classifies leukemia fast and accurately, improving urgent treatment decisions.

Learn how tirzepatide treatment improves diet-related quality of life and satisfaction in Type 2 diabetes patients.

Findings revealed that 17 allergens, already part of the adult EBS, produced positive reactions in at least 1% of children.

Discover a study showing how resistance training can improve inflammation, oxidative stress, and physical performance in patients with liver cirrhosis.

Half of critically ill encephalitis patients face poor outcomes within months, but recovery varies by cause. Keep reading to learn more.

Immune profiles after COVID-19 vaccination predict booster need, with rapid-decliners at higher risk of breakthrough infection.

Discover how LAVImin measured by cardiac MRI outperformed traditional risk factors in predicting adverse outcomes after heart attack, offering a new biomarker for patient risk assessment.

Study reveals genetics and Agent Orange exposure independently boost lymphoma risk among veterans, highlighting the need for targeted screening and prevention strategies.

Discover a study exploring how hyaluronic acid and amino acids work together to accelerate healing in hard-to-heal wounds.

International study links seizure-related breathing interruptions to epilepsy mortality risk, paving the way for improved monitoring and prevention.

The findings demonstrated that GLP-1 RAs were effective in significantly improving several clinical outcomes.

ECPR can restore circulation and tissue oxygenation, substantially improving survival and offering a favourable functional recovery.

Increased tissue magnetic susceptibility in the entorhinal cortex and putamen is significantly associated with the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults.

Cocoa flavanol supplements reduce key inflammatory markers linked to ageing and heart disease. Keep reading to learn their clinical potential.

New bio-inspired robots navigate complex GI environments, offering targeted drug delivery and promising minimally invasive cancer therapies.

New research shows rising rates of breast anaplastic large cell lymphoma among White and Hispanic women, with notable racial and ethnic disparities.

Eating a Mediterranean-style diet rich in plant foods may protect against severe gum disease, while frequent red meat consumption could increase risk.

Black men remain underrepresented in large screening trials, and screening rates declined across all groups after the 2012 US Preventive Services Task Force recommendations.

A UK Biobank study finds abdominal fat significantly raises GERD risk, with stronger associations in women than men.

Oral bacteria and fungi have been identified as risk factors for the development of pancreatic cancer, making them potential non-invasive biomarkers for identifying individuals at high risk.

Watching television for four or more hours daily is linked to increased risk of cognitive decline in adults and older adults, according to a large new meta-analysis.

A Japanese multicentre study has revealed that clinical inertia—the failure to escalate treatment in patients with systemic lupus erythematosus despite active disease—leads to greater organ damage and reduced quality of life.

A recent study has identified the multifunctional protein G3BP1 as a key regulator of lipid metabolism in the liver.

Oral isotretinoin remains the most effective therapy, although its precise mechanism is not fully understood.

nalysis of the BLADDA urothelial cancer registry demonstrated that neoadjuvant chemotherapy was associated with reduced risk of invasive bladder cancer recurrence.

A machine learning model combining CT radiomics with clinical data has shown accuracy comparable to experienced pulmonologists in diagnosing usual interstitial pneumonia and predicting survival outcomes.

A deep learning algorithm has shown promise in improving the risk assessment of lung nodules on CT scans, potentially reducing false positives in lung cancer screening.

A global study covering 204 countries found that fewer than one in four people with diabetes achieved optimal glycaemic control, highlighting persistent gaps in diagnosis and treatment despite improvements since 2000.

Large-scale surveys, such as those conducted by the University of Chicago, align with these findings, reporting crustacean allergy prevalence of around 1.2%.

The results demonstrated a high probability, 97.3%, that shorter durations of antibiotic prophylaxis, including no treatment, were noninferior to longer durations for all-cause mortality.

Updated global criteria standardise diagnosis of vascular cognitive impairment and dementia, incorporating biomarker guidance and preclinical assessment.

Eating a more plant-based, sustainable diet may cut diabetes risk and reduce greenhouse emissions, large UK study finds.

A study from Cairo University Hospital reveals that gastric scintigraphy and the Gastroparesis Cardinal Symptom Index are valuable tools for diagnosing diabetic gastroparesis and predicting treatment outcomes.

Rare genetic variants affecting antiviral, inflammatory, and autophagy pathways may explain severe neurological complications from chickenpox in children.

A new study demonstrates that a modified lung ultrasound (LUS) scoring system can accurately assess severity and prognosis in systemic autoimmune rheumatic disease-associated interstitial lung disease (SARD-ILD).

Patients receiving once-daily upadacitinib 30 mg achieved significantly greater reductions in abscesses and inflammatory nodules compared with historical placebo rates.

Invasive strategy helps relieve angina faster in chronic coronary disease, while conservative care prolongs persistent symptoms, study finds.

A randomised trial finds that blowing a conch shell reduces daytime sleepiness, improves sleep quality, and lowers apnoea severity in people with obstructive sleep apnoea.

A new study has identified the best ways to evaluate the effectiveness of risk-reducing early salpingectomy (RRES) with delayed oophorectomy in women at high genetic risk of ovarian cancer.

Cooler bedrooms and brighter daytimes shown to promote better sleep and wellbeing in people living with dementia, new study reveals.

Appropriate risk assessment before prescribing treatment, along with personalised management strategies, could help reduce the long-term burden of cardiometabolic diseases in this population.

The results revealed that patients with AD displayed a less favourable cardiovascular risk profile.

AI model integrating health outcomes offers more accurate biological age estimates, helping clinicians identify disease risk earlier.

Undiagnosed heart condition affects up to one in six older Black men with heart failure, new research finds.

Researchers have uncovered a central role for Tropomodulin-2 (TMOD2) in promoting colorectal cancer (CRC) progression and liver metastasis.

A landmark trial combining novel therapies has produced the first signs of durable post-treatment HIV control, pointing to a new frontier in functional cure research.

Beyond disease associations, CPAP mask-related skin complications such as dermatitis may arise due to friction, pressure, moisture, or sensitivity to mask materials.

A key finding was that patients treated at specialist centres experienced a significantly shorter delay in switching from immunosuppressants to advanced systemic therapies.

Results showed that bpMRI was noninferior to mpMRI for detecting clinically significant prostate cancer, defined as Gleason Grade Group 2 or higher.

ERS/EULAR guidelines provide detailed recommendations for diagnosing, monitoring, and treating connective tissue disease-related interstitial lung disease, tailored to disease type and risk profile.

SLIT2 protein in eye and blood linked to early cognitive decline, paving the way for new dementia tests.

Researchers are making progress in the fight against neuroblastoma (NB), a challenging childhood tumour known for its resistance to chemotherapy.

In Cohort 1, data from 787 participants revealed that current smokers, who comprised 53.9% of the group, were more likely to present with severe disease.

Evidence shows that early GP intervention and continuity of care are linked with fewer hospital admissions and reduced demand for out-of-hours services.

Discover a study showing that post-treatment AFP levels help predict hepatocellular carcinoma risk in chronic hepatitis C patients after antiviral therapy.

Find out how a new blood test could revolutionise Alzheimer’s diagnosis and care. Keep reading for the latest updates.

Study finds trained dogs detect lung cancer with 78% accuracy from breath samples versus 42% from saliva.

A groundbreaking new tool, Ovatools, is set to transform ovarian cancer diagnosis in UK primary care by providing personalised risk scores that combine CA125 blood test results with a patient’s age.

Prior dengue infection reshapes innate immunity, boosting vaccine efficacy. Vaccination alone fails to replicate these immune changes.

Discover a study linking select autoimmune diseases with increased risks of melanoma and non-melanoma skin cancers, highlighting the need for closer surveillance.

New AI imaging method speeds up antibody discovery for infectious disease treatments, fuelling global pandemic preparedness efforts.

By aligning pretreatment risk stratification more closely with AS eligibility, clinicians may feel more confident recommending surveillance, potentially reducing overtreatment.

Over half of all births in Britain now involve medical intervention, with caesarean deliveries driving the trend, new NHS data show.

Childhood cognitive skills linked to lower mortality risk, but adversity may weaken these protective effects into adulthood.

Previous research has shown that blueberry intake in adults increases beneficial Bifidobacterium species, enhances gut barrier integrity, and reduces inflammation.

Potential mechanisms behind BSV’s protective effect may mirror those described for tenofovir-based therapies, such as modulation of inflammatory and oncogenic pathways.

Occlusion procedure offers safer stroke prevention than anticoagulants for dialysis patients with kidney failure, new study finds.

Global disparities in AMR governance show high-income countries with stronger plans, while low-income nations face weaker strategies and higher infection burdens.

Importantly, patients with clear margins from excisional biopsy alone, who did not undergo wide excision, showed no recurrence after a median of more than eight years.

Air pollution may drive Lewy body dementia by triggering toxic brain protein clumps, new research shows.

This study investigated the microbiota of the distal ileum in patients undergoing iRARC without bowel preparation, using direct sampling during ICUD.

Hospital asthma exacerbations rise in later pregnancy, with reduced inhaled corticosteroid use a key modifiable risk factor, UK data show.

Global RETFound model unites 100 countries to build more equitable, diverse AI for medical research and patient care.

Discover a study exploring how AI can transform allergy and immunology, highlighting challenges, opportunities, and a roadmap for clinical impact.

Emerging evidence points to the role of CD4+ T cell subsets in fuelling MAFLD-related inflammation and fibrosis.

Single-dose MM120 provides fast, lasting anxiety relief in generalised anxiety disorder, paving the way for new treatments.

A 3-month clofazimine- and rifapentine-containing regimen for drug-susceptible TB failed to improve cure rates and caused more severe adverse events than standard therapy, according to the Clo-Fast trial.

Ultraviolet B (UVB) phototherapy is the traditional non-pharmacological approach, promoting repigmentation by stimulating melanin production.

Angiographic AMR index helps predict heart attack patients’ risk of complications after PCI, offering practical guidance for treatment.

Overall, this research offers a practical web-based prediction tool that can support clinicians in tailoring patient follow-up and treatment.

By 2050, nearly half of US adults aged 30–69 will have obstructive sleep apnoea, with cases rising to 76.6 million and the steepest growth seen in women.

Endovascular thrombectomy (EVT) is an established treatment for basilar artery occlusion (BAO) strokes, a rare but often devastating subtype of stroke…

Game-based training slows memory loss and boosts brain health in early dementia, offering hope for patients and families.

Obstructive sleep apnoea (OSA) is a common yet frequently undiagnosed condition among people with Type 2 diabetes…

Discover a study exploring how a traditional Chinese herbal formula significantly reduced symptoms of seasonal allergic rhinitis with minimal side effects.

Learn how new research links major air pollutants with increased NAFLD risk, urging broader public health focus.

Frequent use of artificial sweeteners may speed up memory loss and thinking decline, particularly for those with diabetes.

A study of 226 patients shows virtual rheumatology care is safe and effective, with very low rates of failed visits and no increase in disease-related hospitalizations.

A study of nearly 100,000 UK women trying to conceive revealed that 41% could not correctly identify their fertile window, underscoring the urgent need for improved fertility education.

A recent study introduces an advanced ex vivo 3D micro-tumour testing platform that accurately forecasts individual patient response to chemotherapy, potentially revolutionizing personalized treatment decisions.

New UKHSA data show pre-school booster coverage has fallen to 81.4% in England, below herd immunity thresholds, leaving children vulnerable to outbreaks.

Abelacimab reduces bleeding risk in atrial fibrillation patients, even with kidney disease, study finds.

Central tumour location linked to worse survival in lung cancer, suggesting need for closer post-operation monitoring.

Minimal residual disease (MRD) is a major barrier to curing advanced ovarian cancer, even in patients who appear disease-free after initial therapy. A recent study of 95 patients showed that MRD detected through second-look laparoscopy or circulating tumor DNA strongly predicted shorter progression-free and overall survival.

See how new hair analysis could help detect ALS earlier and simplify diagnosis. Find out more by continuing to read.

Discover how high-intensity exercise offers small but meaningful improvements in depression, especially for older individuals.

Understand how paternal hepatitis B has no significant effect on ART pregnancy or live birth outcomes.

Learn if post-heart attack H. pylori screening prevents gastrointestinal bleeding and who might benefit. Keep reading for insights.

A proteome-wide genetic study found that the protein FSHB is strongly associated with increased risk of endometrioid ovarian cancer.

A study of 261 patients with inflammatory joint diseases found that education, employment, and place of residence significantly influence quality of life, while disease type had little effect.

Mesenteric fat proliferation on MRI scans is linked to higher risks of hospitalization and surgery in Crohn’s disease, suggesting a new imaging marker for long-term outcomes.

Global prevalence of HS, estimated between 0.67–1.46%, surpassed previous estimates, with substantial global variations.

Explore which treatment best suits carotid artery stenosis and stroke risk. Learn how stenting and surgery compare by reading more.

Women remain underrepresented in heart trials, a global review finds, risking gaps in tailored cardiovascular care and outcomes.

Combined liver transplant and sleeve gastrectomy yield lasting weight loss and fewer metabolic complications in patients with obesity.

AI speech analysis detects neurological disorders with over 90 percent accuracy, promising rapid non-invasive screening worldwide.

Childhood cancer survivors who are obese and less physically active face a significantly higher risk of developing subsequent cancers later in life, according to new research….

A Japanese study shows avacopan helps induce remission in MPA and GPA while reducing steroid doses and adverse events, even when serum C5a levels remain unchanged.

While medical treatments remain the cornerstone of care, skincare is increasingly being recognised as a valuable adjunct to therapy.

A study of over 235,000 colonoscopies found that people aged 45–49 had similar polyp and carcinoma detection rates as those aged 50–54, supporting earlier colorectal cancer screening.

Find out how app-based messaging supports diabetes management and reduces cardiovascular risks in adults with poor control. Keep reading.

Understand how an AI model uses chest CT scans to diagnose COPD with 95% accuracy.

A large cohort study using data from the UK Biobank has found that metabolic syndrome is associated with an increased risk of developing Parkinson’s disease, particularly in individuals with a high genetic predisposition.

A groundbreaking AI model, trained on over 1.3 million MRI–pathology pairs, is redefining prostate cancer diagnosis. The MRI‑PTPCa system delivers near‑perfect accuracy in grading tumors, offering a safe, noninvasive alternative to biopsies while improving clinical decision‑making and patient outcomes.

Learn how GLP-1 RAs may cut peptic ulcer risk in diabetes patients by nearly half.

Learn how omalizumab shows high response rates and low side effects in children with chronic spontaneous urticaria.

The team concluded that CLD remains a major health burden in Thailand, highlighting the need for strong prevention strategies, early diagnosis, and equitable access to effective therapies.

AI and imaging mini-cameras now reliably predict future heart attack risk, paving the way for more targeted treatment.

A prospective study highlights that Takayasu arteritis patients with high ischemic deficits on CT perfusion scans face a sharply elevated risk of strokes and other ischemic events.

Medical cannabis linked to better sleep, mood, and life quality in insomnia patients over 18 months, real-world study finds.

Survivors of childhood cancer who live past age 50 face a significantly higher risk of premature death and serious health problems compared with the general population…

Discover how machine learning shows high accuracy for HIV prediction but needs better validation before use in STI clinical practice.

Uncovered self-expanding metal stents (SEMS) and balloon dilation are safe and effective treatments for benign gastric outlet obstruction; however, SEMS should not be the first choice due to its associated cost and complications.

Learn how AI-driven skincare improved acne and quality of life more effectively than self-chosen products in recent clinical trial.

AF screening with an ECG patch led to a modest increase in AF diagnosis at 2.5 years

Integrating routine hormone testing with pelvic floor ultrasound assessments could help identify high-risk women early.

A nearly three-decade study has revealed a significant rise in triazole-resistant Aspergillus fumigatus, a fungus responsible for invasive aspergillosis…

Understand how chamber volume ratios on MRI predict cardiac risk, even when heart chambers fall within normal size limits.

Focal epilepsy study shows most patients need over a year and multiple medications to gain seizure control.

A new study has revealed how subtle oxidative modifications of proteins fine-tune cell division and determine how cells respond to stress. Read on to learn more!

Discover how HBV immunity is linked to lower diabetes risk, suggesting added value of hepatitis B vaccination.

The introduction of the jab is intended to cut cases of chickenpox and reduce the disruption it causes for families.

Discover a study exploring how verbal instructions and symptom expectations influence fatigue and motivation in people living with primary biliary cholangitis.

Hormonal birth control may affect how women regulate emotions and remember negative events, new research suggests.

A retrospective study has found that male sex and rapidly progressive interstitial lung disease are strong predictors of poor survival in patients with anti-MDA5 dermatomyositis.

Study shows diets high in saturated fatty acids drive lung inflammation and worsen airway disease, similarly to obesity-related asthma.

A major UK-based study has revealed a new link between ageing, DNA changes and the development of blood cancers….

Three monoclonal antibodies targeting monkeypox A35 protein protect mice and improve outcomes, highlighting potential for new therapies.

People with gastrointestinal disorders face a higher risk of sleep problems, including insomnia and shorter sleep duration, according to a large U.S. study.

Discover a study evaluating combined dye and alexandrite laser therapy, offering promising results for improving outcomes in patients with papulopustular rosacea.

The model was subsequently applied to 11,723 examinations in men who had no documented diagnosis of prostate cancer at the time of MRI, with an average patient age of 65.5 years.

Learn how alternate-day iron dosing may be as effective as daily treatment for IDA, with fewer side effects.

A large UK study links certain additives in ultra-processed foods, such as flavourings and sweeteners, to increased risk of death.

The study found that almost 8% of individuals aged two years and above had asthma, while more than half (52.3%) reported allergy symptoms.

The findings suggest that a multi-marker, multi-pathway approach can account for the heterogeneous ways HCC emerges.

The MAPLE-HCM trial shows aficamten improves exercise capacity and symptoms more than metoprolol in symptomatic obstructive hypertrophic cardiomyopathy.

In-hospital initiation of SGLT2 inhibitors is safe and may lower early cardiovascular death, worsening heart failure, and mortality in hospitalised patients.

To investigate the feasibility of RUTF for children with SCA, the SAMS trial in Nigeria enrolled 108 children aged five to twelve with severe acute malnutrition.

A new study suggests that the common cold may boost children’s antiviral defences, lowering the risk and severity of COVID-19.

A mobile health program significantly lowered blood pressure among users, with women—especially postmenopausal—showing greater improvements than men.

The POTCAST trial shows raising plasma potassium to high-normal levels reduces ventricular arrhythmia risk, hospitalisations, and death in ICD patients.

Objective biometric measures showed improvement in both groups, but the combination therapy produced significantly greater benefits.

DIGIT-HF shows digitoxin reduces death and hospitalisation in advanced heart failure, offering an additional option for high-risk patients on top of standard therapy.

A large study finds age strongly increases arrhythmia risk, while higher fitness levels protect against atrial ectopy in asymptomatic adults.

With limited early-detection tools and only modest improvements in survival for advanced disease, clinicians urgently need reliable biomarkers to improve prognostication.

Airway bacteria like Streptococcus oralis may boost natural immune defences, helping protect against pneumonia and viral infections, new research suggests.

A study finds that CML patients with the e13a2 BCR-ABL1 transcript show poorer molecular responses to imatinib compared to those with e14a2, suggesting transcript type may influence treatment outcomes.

Automatic chest compression devices outperform manual methods for CPR in simulated zero gravity, with piston devices meeting guideline-recommended standards.

A major analysis finds Afro-American patients with hypertension face higher cardiovascular morbidity, while Asian patients carry a greater risk of stroke.

A recent mixed-methods study evaluated NOURISH-US, a revised food-supplement programme designed to ease costs for households with a child aged 12 or younger managing any food allergy.

This nationwide South Korean cohort study examined over six million young adults aged 20–39 years to assess new-onset AF according to contemporary SLD subtypes.

A nationwide study of more than 66,000 rheumatoid arthritis patients undergoing joint replacement found that blood transfusions are declining but remain linked to higher complication risks, especially in older adults and those with comorbidities.

A study of over 3,400 women aged 50+ found that while sexual dysfunction was common in both midlife and older women, those aged 65 and above reported less distress, suggesting shifting expectations and perceptions with age.

A new study finds that PD-1 inhibitors combined with chemotherapy achieved a 97.7% disease control rate and median progression-free survival of 13.5 months in advanced gastric cancer patients.

Lower vitamin D levels linked to higher thyroid cancer risk, new meta-analysis suggests clinical importance.

FMT and microbiome therapies significantly outperform antibiotics in recurrent C. difficile infection, with cure rates up to 91% and favourable long-term safety.

Clinical examination is limited by visual similarity between benign and malignant lesions and imperfect diagnostic accuracy.

Find out who benefits most from catheter ablation for atrial fibrillation according to new research. Keep reading to learn more.

Discover a study showing lasting survival gains from treatment intensification in prostate cancer.

COVID-19 infection raises risks of asthma, rhinitis, and sinusitis, while vaccination reduces respiratory type-2 inflammatory disease incidence.

Learn how a new scan shows promise for staging invasive lobular breast cancer with 100% specificity in small feasibility study.

Explore how new AI technology speeds up whole-slide cancer analysis for better research and treatment strategies. Keep reading.

A four-year prospective study finds that breast cancer survivors experience improvements in depression, anxiety, pain, and quality of life after treatment, though women who underwent mastectomy reported higher long-term anxiety than those who had breast-conserving surgery.

Discover how tirzepatide aids weight loss and insulin reduction in Type 1 diabetes with no increase in hypoglycaemia.

Discover a study showing how early milk exposure accelerates tolerance in children with CMPA.

Specialists have described the approval as one of the most promising developments in decades for bladder cancer care.

Prenatal pesticide exposure linked to brain abnormalities and motor deficits in children, new MRI study shows.

Understand how microwave ablation effective and safe for hyperthyroidism, especially with benign nodules

Understand how women with Type 1 diabetes have greater cardiovascular risk than those with Type 2.

Players completed a battery of computerised and pen-and-paper tests spanning visual perception, visuomotor vigilance, visuospatial short-term memory and executive functions.

Study finds timing of mirabegron dosing affects symptom relief and emotional outcomes in women with overactive bladder.

Understand familial and autoimmune risk patterns in alopecia areata, supporting genetic counselling and family screening.

Respiratory viruses such as influenza and SARS-CoV-2 can awaken dormant breast cancer cells, driving metastasis and raising mortality risk in cancer survivors, new research finds.

Learn how deep phenotyping from health records may improve obesity treatment selection. Keep reading to discover future possibilities.

Tezepelumab reduces exacerbations and enhances lung function and quality of life in severe, uncontrolled asthma.

A systematic review shows high-intensity interval training (HIIT) is safe for patients with inflammatory arthritis.

Researchers at Mount Sinai have reported new evidence that prenatal acetaminophen use may be linked to an increased risk of autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) in children.

A major new study has identified critical factors that increase the risk of invasive fungal infections in adults with blood cancers and those undergoing haematopoietic stem cell transplantation….

A study finds that elevated trimethylamine N-oxide (TMAO) levels are linked to increased risk of abdominal aortic aneurysm development, faster aneurysm growth, and higher likelihood of surgical intervention.

A case series has reported the first successful use of combined liver and haploidentical stem cell transplantation to cure patients with severe sickle cell disease (SCD) complicated by advanced liver failure.

COVID-19 survivors, especially women, show signs of vascular ageing, highlighting new risks for long-term heart health.

A new study shows women with Alzheimer’s disease have lower levels of omega fatty acids in their blood, pointing to a potential protective role for these fats.

Delgocitinib ointment could be an effective and safe option for patients with face or neck atopic dermatitis (AD) who are concerned about the side effects of topical steroids or tacrolimus

Nonviral gene therapy to boost brown fat molecule reverses age-related heart dysfunction in animal studies.

The present study assessed the efficacy of sub-anaesthetic esketamine for CRBD prevention in patients undergoing ureteroscopic lithotripsy.

A registry-based analysis using Bayesian modelling has mapped the pathways linking biomarkers, lung function, and comorbidities to severe asthma exacerbation risk.

Over half of chronic pain patients discontinue medical cannabis within a year, highlighting need for individualised care.

A new study has shown that a leukaemia stem cell (LSC)-based test may outperform traditional methods in predicting relapse in acute myeloid leukaemia (AML) patients after stem cell transplant…

Against this backdrop, the gut–lung axis has emerged as a persuasive framework for understanding disease heterogeneity.

Emerging evidence also implicates air pollution in metabolic disorders common in later life, including dyslipidaemia, weight gain and impaired glucose homeostasis.

A new study reveals that rheumatic patients on JAK inhibitors have weaker T cell responses to SARS-CoV-2 vaccination compared to those on TNF inhibitors.

A large US study has found that the risk of developing second primary cancers after radioactive iodine treatment for differentiated thyroid cancer varies by age group.

A Ugandan trial has found artemether-lumefantrine less effective than other ACTs, with malaria resistance mutations linked to delayed parasite clearance.

A study of nearly 300 women with obstructive defecation syndrome found that combining transperineal ultrasound with anorectal manometry offers a clearer picture of pelvic floor structure and function.

Biomarker analyses continue to provide insights but have not yet established clear rules for patient selection.

Wireless sweat patch matches lab accuracy for cystic fibrosis monitoring, promising home-based disease management.

The TALAPRO-2 study enrolled 805 patients from 200 centres across 26 countries, including North America, Europe, Israel, South America, South Africa, and the Asia–Pacific region.

A UK registry study shows asthma biologics improve outcomes across BMI groups, but obese patients remain more likely to have uncontrolled disease.

A promising new study has identified a highly accurate, non-invasive method to diagnose non-small cell lung cancer (NSCLC) using a blood test based on tRNA signatures.

This study evaluated a clustered nursing care model, delivered via an online platform, for adults with atopic dermatitis.

In this randomised prospective study, 72 living liver donors scheduled for right hepatectomy were enrolled and divided into two groups.

A randomised double-blind trial in Kosovo found that 4,000 IU of vitamin D daily significantly reduced pain and disease activity in rheumatoid arthritis patients after six months of treatment.

Study finds no long-term cardiovascular benefit from aspirin in healthy older people, but highlights increased bleeding risk.

Researchers analyzed over 6,500 treatment episodes between January 2017 and December 2020, with follow-up through June 2024

A Phase 1 USA trial finds novel oral polio vaccines nOPV1 and nOPV3 to be safe, highly immunogenic, and comparable to Sabin-strain vaccines, paving the way for Phase 2 studies.

A large safety analysis of infliximab and adalimumab in pediatric inflammatory bowel disease highlights the need for continued postmarketing monitoring, with new concerns emerging for long-term infliximab use.

By Month 6 (M6), 50–60% achieved at least a one-point improvement across validated HS severity measures.

Wearables reveal unique activity and heart rate patterns in long COVID, showing promise as clinical biomarkers.

Taken together, the findings suggest that targeted augmentation of cholinergic signalling may help bridge the gap between anatomical de-obstruction and functional recovery in BOO-mediated UAB.

A large pooled analysis shows that kidney problems are common in PAH and CTEPH, worsen survival, and see only minor improvement with current pulmonary hypertension therapies.

Dopamine changes link to psychotic symptoms, suggesting new treatment avenues for mood disorders with psychosis.

A new bispecific antibody therapy, AFM28, has shown strong preclinical results in targeting treatment-resistant cells in acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), according to new research.

Intermittent fasting decreased symptoms of long COVID-19 in a randomised crossover trial that compared the efficacy and safety of 4 weeks of 1–2-day fasting plus a restricted diet versus 4 weeks of mild time-restricted eating and a restricted diet

Silymarin, vitamin E, and phospholipids combination therapy effectively reduces liver steatosis, fibrosis, and metabolic risk in MASLD.

Discover how stopping smoking may improve recovery from other addictions and why treatment programmes should integrate both.

A new study reveals that over a third of Indian rheumatoid arthritis patients experience methotrexate intolerance, with many reporting symptoms like nausea and abdominal discomfort.

A Vietnamese retrospective study challenges the push for endoscopy within 12 hours in patients with esophageal variceal bleeding.

Discover a study comparing intralesional triamcinolone and methotrexate for alopecia areata, revealing superior regrowth and patient satisfaction with triamcinolone.

TriCLASP study confirms PASCAL T-TEER safely reduces tricuspid regurgitation and improves symptoms and quality of life.

While MRI performance does not appear to depend on testosterone and inter-reader agreement is high, open questions remain, including whether PSMA PET or genomic markers could further refine early detection.

Ultrasound is an effective screening tool for steatotic liver disease, provided that inter- and intra-observer comparisons are incorporated to enhance diagnostic consistency.

A multidimensional framework revolutionises traumatic brain injury characterisation, offering more personalised and accurate care.

Total potato intake was positively associated with risk of developing Type 2 diabetes, but this effect was primarily driven by intake of French fries.

Both groups demonstrated significant improvements over pretreatment at every follow-up, one week, one month, three months and six months.

A large-scale study in Guangzhou has found that irregular sleep patterns, insufficient rest, and late bedtimes may reduce a woman’s chances of conceiving.

A new study in npj Women’s Health has found that machine learning models used to diagnose bacterial vaginosis may underperform in Black women.

A new study demonstrates that fecal calprotectin levels, measured using fluorescent immunochromatography assay (FICA), strongly correlate with disease activity in ulcerative colitis, offering non-invasive thresholds to better guide patient care.

Exc: Adults received three consecutive FMTs, either allogeneic (from healthy donors) or autologous (their own stool), with liver fat measured by MRI-derived proton density fat fraction.

Portable $2 test detects deadly infections from a drop of blood within 15 minutes, with unmatched sensitivity.

This study evaluated the psychometric performance and interpretability of HiSQOL using data from two multinational Phase III trials of bimekizumab in moderate-to-severe HS.

Semaglutide improves cardiovascular risk factors but raises health care costs, finds large multicentre cohort study.

The authors hypothesised that, in women with OAB, the additional sympathetic blockade produced by spinal anaessthesia would further unmask parasympathetic dominance.

An AI-driven drug discovery platform has created new antibiotics with unique mechanisms against drug-resistant N. gonorrhoeae and MRSA, showing success in preclinical models.

Men with dementia show higher mortality and hospitalisation rates than women, according to major US Medicare study.

In a prospective study measuring the 14 most abundant HMOs in colostrum and at three months postpartum, researchers tested whether maternal supplementation with ω-3 polyunsaturated fatty acids alters HMO profiles.

Discover a study assessing whether a five-minute rapid antibody test can speed up hepatitis C diagnosis. Read on.

In a long-term real-world study, researchers found that flare-based rituximab retreatment for rheumatoid arthritis maintained high drug retention but led to cycles of fluctuating disease activity and wellbeing.

In a new study, researchers show that the human fertility gene PRSS55 can restore reproductive function, laying the groundwork for non-hormonal male contraceptive development and highlighting new genetic targets for future fertility control strategies.

Researchers developed a novel vaginal synbiotic (VS-01) comprising three L. crispatus strains isolated from women with stable, optimal microbiomes.

New research suggests that PRO-C16, a blood-based marker of type XVI collagen formation, may help detect intestinal fibrosis in patients with Crohn’s disease.

A recent study evaluated a novel 2% salicylic acid gel enriched with hydrating and soothing agents, aiming to balance acne treatment with skin barrier repair.

Researchers have developed a PSA-based index incorporating MRI measurements of periprostatic fat that significantly improves the prediction of high-grade prostate cancer.

TEER linked to reduced deaths and heart failure hospitalisations in atrial functional mitral regurgitation patients, study shows.