Uncategorised - European Medical Journal

Neddylation and Hepatic Zonation: Insights Into Liver Metabolism and Diseases

The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along the lobule…

How to Identify MASLD Forms Secondary to Endocrine Derangements

Secondary forms of metabolic dysfunction-associated steatotic liver disease (MASLD) have different pathogeneses, outcomes…

Niche-Specific Reprogramming of Macrophages During Pro-Senescence Therapy in Liver Cancer

Hepatocellular carcinoma (HCC), the main form of primary liver cancer, is an increasingly prevalent and highly heterogeneous disease…

Phosphatidylethanol in Steatotic Liver Disease: EASL Congress 2025

ACCURATELY discerning the contribution of alcohol intake to the pathogenesis of steatotic liver disease (SLD) is fundamental to it…

Timing of Anticoagulation in Variceal Bleeding with Portal Vein Thrombosis

Portal vein thrombus (PVT) is characterised by narrowing or blockage of the portal vein by a blood clot. Obstruction may be complete…

MASH Redefined: Insights from the EASL Congress 2025

THE EUROPEAN Association for the Study of the Liver (EASL) Congress 2025, Amsterdam, the Netherlands, placed patients and…

Mitigation of Immune Dysfunction in Patients with Hepatitis B after siRNA Treatment

A chronic hepatitis B (CHB) infection is characterised by host immune dysfunction related to a high viral antigen load. The restoration of…

Albumin Therapy for Decompensated Cirrhosis: EASL Congress 2025

THE MANAGEMENT of decompensated cirrhosis remains a formidable challenge in hepatology, owing to its multifaceted complications…

Hepatocyte–Neutrophil Interaction Is Key in the Pathogenesis of Alcohol-Associated Hepatitis

Alcohol-associated hepatitis (AH) is the most severe form of alcohol-related liver disease (ALD), which is characterised by an impairment…

EASL 2025 Abstract Highlights

The following highlights showcase late-breaking research presented at the European Association for the Study of the Liver (EASL) Congress…