Uncategorised - European Medical Journal

AMR Governance Improving, But Resistance Still Rising - EMJ

AMR Governance Improving, But Resistance Still Rising

Global AMR governance has improved, but antimicrobial resistance remains high, highlighting gaps in policy implementation and surveillance.

Ammonia Buildup linked to Liver Tumours in Mice - EMJ

Ammonia Buildup Linked to Liver Tumours in Mice

Mouse study finds impaired ammonia clearance can accelerate hepatocellular carcinoma growth and highlights potential dietary strategies to slow tumours.

Ultrasound Characterisation of Uterine Fibroids - EMJ

Ultrasound Characterisation of Uterine Fibroids

Analysis of fibroid subtypes reveals unique ultrasound patterns and clinical profiles, helping differentiate usual-type from variant uterine fibroids.

Revisiting Erythroid Response to Luspatercept in the Phase III BELIEVE Trial Using Real-World Response Criteria

Patients with TDT have impaired erythropoiesis and face a chronic treatment burden of regular transfusions and iron chelation therapy to…

Sibeprenlimab Trial Shows Benefit in IgA Nephropathy - EMJ

UKKW 2026: Sibeprenlimab Reduces Proteinuria in IgA Nephropathy Trial

Interim results from the Phase III VISIONARY trial show that sibeprenlimab significantly reduced proteinuria and improved disease biomarkers in patients with IgA nephropathy.

Weight Loss Drugs May be More Effective in Women than Men

GLP-1RAs produce greater weight loss results among women than men, a 2026 systematic review and meta-analysis has found.

eGFR equations vs measured GFR in CKD study - EMJ

UKKW 2026: CKD Study Questions Accuracy of Widely Used eGFR Equations

A large UK study finds commonly used eGFR equations may overestimate kidney function, potentially delaying chronic kidney disease diagnosis and treatment.

Anti-Emetic Drug Reduces Seizures in Temporal Lobe Epilepsy

Administration of prochlorperazine or CLP-257 (or its prodrug CLP-290), significantly decreased seizure frequency in vivo, providing further evidence that enhancing KCC2 function could stabilise neuronal networks.

Individualising HDF Convection Volume in Dialysis Care - EMJ

UKKW 2026: Individualised Haemodiafiltration May Aid Clearance

A study suggests convection volume in haemodiafiltration may be tailored to patient weight and residual kidney function to optimise middle-molecule clearance.

Scientists Discover ‘Indispensable’ Protein for Malaria Parasite

Scientists have discovered a protein, Aurora-related kinase 1, that is “indispensable” for malaria parasite survival.