Uncategorised - European Medical Journal

doctor and female patient discussing ovarian cancer

PARP Inhibitors Extend Control in Ovarian Cancer

PARP inhibitor maintenance therapy improved progression free survival in newly diagnosed advanced ovarian cancer but not survival.

How the Brain Changes Across Five Life Stages

Discover how the brain’s structural networks evolve in five distinct phases across the human lifespan, from childhood to late ageing.

Female stroke survivor performing weight training during assessment of stroke neuromuscular fatigability

Stroke Neuromuscular Fatigability Differs Significantly Between Sexes

To explore sex specific effects of stroke on motor performance, investigators studied 41 chronic stroke survivors at least six months after stroke and 23 age matched neurotypical adults.

Dupilumab Improves Quality of Life in Chronic Urticaria

A phase 3 trial shows dupilumab significantly improves quality of life in omalizumab-naïve patients with chronic spontaneous urticaria.

Dual Approach Shows Promise in Advanced KRAS G12C-Mutated Lung Cancer

Dual Approach Shows Promise in Advanced KRAS G12C-Mutated Lung Cancer

Combining glecirasib and sitneprotafib shows encouraging efficacy and safety in patients with KRAS G12C-mutated NSCLC.

Clinician using point-of-care PCR for suspected Mycoplasma pneumoniae pneumonia in the emergency department.

Rapid Point-of-Care Testing Optimizes Antibiotic Use

Community-acquired pneumonia caused by Mycoplasma pneumoniae can be difficult to recognize at first presentation in the emergency department.

Assorted dietary iron rich foods including red meat, liver, beans, lentils, eggs and spinach arranged around a notebook, illustrating dietary iron deficiency and immune health.

Dietary Iron Deficiency Compromises Influenza Immunity

Dietary iron deficiency during influenza infection may leave memory T cells numerically intact yet functionally weakened.

New Stem Cell Approach Paves Way for Type 1 Diabetes Cure

New Stem Cell Approach Paves Way for Type 1 Diabetes Cure

Scientists used a chemotherapy-free stem cell approach to reverse type 1 diabetes in mice, restoring insulin production and immune balance without long-term medication.

UK Immunology Services Facing Critical Workforce Shortages

UK Immunology Services Facing Critical Workforce Shortages

A new BSI-CIPN report warns that UK clinical immunology and allergy services are critically understaffed, calling for urgent national workforce planning and investment.

S100A11 -HK2

S100A11-HK2 Axis Emerges as Promising Target in MASH

Silencing S100A11 protects against steatosis, inflammation and fibrosis in murine MASH, uncovering HK2 as a key metabolic driver and potential therapeutic target.