Dermatology

Genital discoid lupus may mimic common inflammatory dermatoses, making biopsy critical in chronic genital rashes.

Chronic prurigo recommendations clarify diagnosis, severity assessment, and personalized treatment pathways for patients with persistent itch.

SCALE 2026 highlighted medical dermatology updates spanning lasers, rosacea, acne, skin aging, and photoprotection.

GLP-1 weight loss may intensify aesthetic concerns linked to skin laxity, muscle tone, and body contouring.

Head and neck skin lesions require precise excision to reduce recurrence and preserve cosmetic outcomes.

Online patient discussions suggest JAK inhibitors may generate stronger treatment satisfaction in atopic dermatitis care.

Upadacitinib acne affected nearly half of surveyed patients with IBD and sometimes changed treatment decisions.

Compounded tirzepatide use may be associated with persistent facial nodules after filler and toxin injections.

Skin cancer screening remains inconsistent among solid organ transplant recipients, despite sharply elevated post-transplant malignancy risk.

Actinic keratosis may be driven by inflammation and microbiome imbalance alongside ultraviolet-induced genetic damage.

Environmental and lifestyle exposures significantly influence acne development through complex biological and social mechanisms.

Psychopharmacology is emerging as a critical tool in dermatology, with growing evidence supporting its role in managing both skin conditions and associated psychiatric disorders.

AI tools may help consumers identify skin conditions more accurately, but guidance on next steps still needs improvement.

Vitiligo stigma varies across cultures, but its psychological toll is global, severe, and too often underestimated.

Cosmetic adverse reactions may cause lasting skin damage, especially in younger patients and those with allergy histories.

A new skin cancer risk stratification tool for solid organ transplant recipients shows strong international validation but inconsistent clinical adoption.

Truncal acne may require more tailored treatment because truncal skin differs structurally and functionally from facial skin.

Deucravacitinib showed strong short-term psoriasis responses and excellent scalp clearance in real-world clinical practice.

Cell-free secretome therapy restored hair growth in preclinical androgenic alopecia models by protecting papilla cells.

Patients with severe alopecia areata treated with upadacitinib achieved greater hair regrowth at Week 24 versus placebo.

Patients with moderate-to-severe atopic dermatitis showed generally low long-term upadacitinib safety event rates across ages.

Continuous secukinumab treatment showed sustained hidradenitis suppurativa lesion control through 4 years in responding patients.

Remibrutinib improved itch and hive severity within 12 hours in chronic spontaneous urticaria in Phase III analysis.

Serum sickness after botulinum toxin type A may signal a rare delayed systemic immune reaction. Read more.

Microneedle patches may improve hyperpigmentation treatment by enhancing skin delivery, efficacy, and tolerability of active agents.

Definisse KP1 eye contour cream may enhance eye rejuvenation when combined with onabotulinum toxin A. Read more.

Fractional CO2 laser improved post-acne scars more than microneedling radiofrequency, but with greater pain and downtime.

Delgocitinib cream significantly improved quality of life in adults with moderate to severe Chronic Hand Eczema (CHE) in pooled phase III trial data.

Abrocitinib appears durable and well tolerated in patients with moderate-to-severe atopic dermatitis (AD), also known as eczema, according to a 2-year retrospective real-world study.

Pazopanib shows activity and manageable safety in paclitaxel-pretreated cutaneous angiosarcoma, offering a potential second-line therapy option.

Patch testing in hand and foot eczema frequently showed no allergen, yet potassium dichromate topped positive results overall here.

Analysis finds 2030 skin-related neglected tropical diseases milestones off track as DALYs increase heterogeneously across nations.

Large language models in glaucoma show promise for education and decision support, yet performance varies widely.

GPT-4 learning models in dermatology demonstrated substandard information yet rarely offered harmful advice in evaluation, overall.

Roflumilast for psoriasis improved Global Assessment scores and was well tolerated versus placebo by Week 8 in a systematic review.

After vunakizumab discontinuation, many plaque psoriasis patients maintained PASI 90, but BMI and interruptions predicted relapses.

Botanical extracts provided negligible nutrition however could increase element exposure; inorganic arsenic and lead were concerns.

Mini-CEX self-assessment training plus feedback improved dermatology residents’ exam skills and rating alignment well in practice.

Perioperative liposomal bupivacaine injections showed minimal adverse events in 129 dermatologic surgery patients in a new review.

A review found seven hidradenitis suppurativa patient-reported key outcome measures, with HiSQOL-17 performing best across studies.

Risankizumab delivered sustained psoriasis clearance and reduced subclinical inflammation on OCT imaging across 52 weeks follow-up.

Real-world PsoBest data show apremilast improved psoriasis severity, involvement, and quality of life over 12 months in usual care.

An overview highlights combination strategies that improve stretch marks through Fitzpatrick phototypes in practice for clinicians.

Real-world meta-analysis found tildrakizumab substantially improved plaque psoriasis severity and quality of life through 52 weeks.

Indoor tanning bed use substantially raises melanoma, BCC, and cSCC risks, underscoring this well-established carcinogenic profile.

In children, deficiencies in zinc and vitamin D independently increased tinea capitis risk and lowered 8-week clinical cure rates.

Bimekizumab showed the strongest short-term efficacy among hidradenitis suppurativa biologics in trials assessed at Week 12 to 16.

Chronic spontaneous urticaria in SLE was not linked to higher disease activity, but was associated with distinct clinical and laboratory risk factors.

Large spot picosecond lasers potentially improve dermal pigment clearance in Asian skin while reducing perilesionaltissue exposure.

Abrocitinib treatment can be personalized in moderate-to-severe atopic dermatitis using flexible dosing to meet disease trajectory.

A cross-sectional study has found variability in how ChatGPT performs when asked to generate informed consent forms for cosmetic dermatology procedures that use lasers and energy-based devices.

In Mohs patients, keratinocyte carcinoma quality of life worsened more with younger age, female sex, and field cancerization class.

Better metabolic control may meaningfully lower psoriatic arthritis risk for many patients living with psoriasis today.

New research suggests salivary oxidative stress markers alone may not distinguish active from inactive Behcet’s disease.

Lasers and energy-based devices may target cellular senescence, potentially rejuvenating aging skin at a fundamental molecular level.

Intradermal botulinum toxin A for post acne erythema outperformed broadband light in this split face randomized controlled trial.