Hema Now | Episode 20
In this episode of Hema Now, host Jonathan Sackier is joined by Kevin Rouault-Pierre and Onima Chowdhury, to explore the biological mechanisms behind MDS, with a spotlight on SF3B1 mutations. From epigenetic stress to diagnostic strategies, this discussion bridges laboratory research and frontline care.
Apple | Amazon Music | YouTube | Download MP3 (41 mins)
Kevin Rouault-Pierre
Kevin Rouault-Pierre is a Reader in Stem Cell Biology and Disease at the Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, UK. He investigates how haematopoietic stem cells respond to intrinsic and extrinsic stresses, with a focus on malignant transformation.
Onima Chowdhury
Onima Chowdhury is a Consultant Haematologist at Oxford University Hospitals, UK. Her work focuses on clonal haematopoiesis, myelodysplastic syndromes, and rare conditions such as vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome, combining clinical care with translational insight.
Timestamps
01:11 – Quickfire Round
07:11 – Haematology Misconceptions
10:56 – Understanding MDS
18:42 – Treating Myeloid Malignancies
23:20 – Epigenetic Mechanisms
28:30 – MDS Treatment Approaches
34:56 – Three Wishes
The opinions expressed in this episode belong to the speakers and do not necessarily represent the opinions of EMJ.
