CT Test Can Assess Risk in Patients with Angina - EMJ

CT Test Can Assess Risk in Patients with Angina

1 Mins

NOVEL CT testing is able to identify risk in patients with angina, and identify those whose angina is stable with a reduced risk of 3-year adverse outcomes. Researchers assessed outcomes of patients undergoing CT angiography and CT angiography-derived fractional flow reserve (CT-FFR), which stimulates the amount of blood that flows through coronary arteries through CT angiography images, artificial intelligence algorithms, and computational fluid dynamics.

Usually, a non-contrast enhanced cardiac CT is performed before CT angiography to evaluate the amount of coronary artery calcium, which is a marker for total coronary plaque. The study group included 900 participants with new onset stable coronary artery disease, with at least one coronary artery stenosis greater than 30% and no prior coronary revascularisation or atrial fibrillation. Of these, 523 had normal CT-FFR results, with a rate of 3-year adverse outcomes of 2.1%, and 377 had abnormal results, with an adverse outcome rate of 6.6%. Patients with abnormal CT-FFR results and a high coronary artery calcium score had an adverse outcome rate of 9.0%, compared with 2.2% in those with a high calcium score and normal CT-FFR results.

This study shows the prognostic potential of CT-FFR in these patients. Lead author Kristian Madsen, University Hospital of Southern Denmark, Esbjerg, stated: “Regardless of the patient’s baseline risk and extent of coronary artery disease measured by coronary artery calcium, if CT-FFR results are normal, the prognosis is good.” Madsen further explained that the diagnostic performance of CT-FFR is high, with results that correlate well with invasively measured fractional flow. “In my opinion, CT-FFR is the best option because it provides a blood-flow estimate similar to what you would obtain if you performed invasive heart catheterisation,” Madsen stated. Contrary to invasive procedures, you can get a reliable and quick answer without the need for additional testing.

The use of CT-FFR will allow clinicians to evaluate risk level of their patients with coronary artery disease, and focus on improving the prognosis of those who are at highest risk.

Please rate the quality of this content

As you found this content interesting...

Follow us on social media!

We are sorry that this content was not interesting for you!

Let us improve this content!

Tell us how we can improve this content?