Refractory Chronic Cough: The Journey from Recognition to Management - European Medical Journal

Refractory Chronic Cough: The Journey from Recognition to Management

Respiratory

This podcast was initiated, funded and approved by GSK and is intended for healthcare professionals only.


The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of GSK or EMJ. The speakers have received honoraria for their participation in this recording.

Episode 1: Unmasking the Unrelenting Cough: Refractory Chronic Cough Through Patient and Practitioner Eyes.

In this first podcast, we explore the challenges of recognising Refractory Chronic Cough (RCC) from both patient and practitioner perspectives. Learn about the common diagnostic challenges and hear real-life experiences that highlight the importance of achieving diagnosis and how healthcare professionals can better support those living with RCC.

Speakers

Anju Peters1

Ludger Klimek2,3

Mandy Beadnell4

1. Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

2. University of Mainz, Germany

3. Center for Rhinology and Allergology, Wiesbaden, Germany

4. Patient advocate for Refractory Chronic Cough.

References

  1. Irwin RS, Madison JM. Unexplained or refractory chronic cough in adults. N Engl J Med 2025;392:1203-14. doi: 10.1056/NEJMra2309906
  2. Lim, K. (2014). Neurogenic cough. Journal of Allergy and Clinical Immunology, 133(6), 1779-1779.e3
  3. Dicpinigaitis PV. Prevalence of stress urinary incontinence in women presenting for evaluation of chronic cough. ERJ Open Res. 2021;7:00012–2021
  4. Chung KF, McGarvey L, Song WJ, Chang AB, Lai K, Canning BJ, Birring SS, Smith JA, Mazzone SB. Cough hypersensitivity and chronic cough. Nat Rev Dis Primers. 2022 Jun 30;8(1):45. doi: 10.1038/s41572-022-00370-w
  5. Morice AH, Millqvist E, Bieksiene K, et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020 Jan 2;55(1):1901136. doi: 10.1183/13993003.01136-2019.
  6. Ding H, Shi C, Xu X, Yu L. Drug-induced chronic cough and the possible mechanism of action. Ann Palliat Med. 2020 Sep;9(5):3562-3570. doi: 10.21037/apm-20-819. Epub 2020 Sep 2.
  7. Irwin RS, French CL, Chang AB, Altman KW. Classification of cough as a symptom in adults and management algorithms: CHEST guideline and expert panel report. Chest 2018;153(1):196–209. doi:10.1016/j.chest.2017.1 0.016
  8. Stolz D, Smith JA, Beadnell M. The significance and psychosocial burden of refractory chronic cough: interview with two key opinion leaders and a patient. EMJ Respir 2025;13[Suppl 1]:2–11. doi: 10.33590/emjrespir/KDKB1418

NX-GBL-CML-WCNT-250008 | August 2025

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