Microbiology & Infectious Diseases

Administering antibiotics more than 1 hour after emergency department presentation for suspected sepsis significantly increases the risk of 28-day in-hospital mortality.

Capillary lactate levels strongly correlate with venous lactate and predict outcomes in patients with sepsis.

Ensitrelvir reduces risk of COVID-19 in household contacts when administered within 72 hours of symptom onset.

UKHSA data reveal that imported dengue cases in England, Wales, and Northern Ireland have reached their highest level since surveillance began in 2009.

New evidence suggests that a 7-day course of antibiotics is as effective as a 14-day regimen for most patients with Gram-negative bloodstream infections.

New findings highlight the potential of once-yearly intramuscular lenacapavir for PrEP, offering a long-acting alternative that could reduce barriers to HIV prevention.

The ECDC reports an alarming 10% rise in childhood tuberculosis cases across Europe, stressing the urgent need for enhanced prevention, diagnosis, and treatment.

A first-in-human study evaluating a novel long-acting injectable antiretroviral therapy has provided promising early results on its safety and pharmacokinetics.