Neurology

Despite the setback, hope remains, with 138 dementia drugs currently in trials, experts say more effective, safer options may soon emerge.

Blood biomarker sNfL predicts MS relapses up to a year in advance, offering new hope for earlier intervention.

AI tool GPT-4o boosts diagnosis accuracy for nerve disorders, helping non-specialists match expert recommendations in real cases.

Frequent nightmares accelerate ageing and triple risk of early death, highlighting a new target for preventive healthcare.

A routine blood test for insulin resistance can predict which Alzheimer’s patients are at risk of rapid cognitive decline.

Nighttime heart rate variability may reveal hidden risks for stroke, depression, and dementia, years before symptoms appear.

Oral bacteria migrating to the gut may drive dementia risk in Parkinson’s, offering new hope for early intervention.

A large meta-analysis suggests TMS improves clinical outcomes in OCD and nicotine dependence, but the role of symptom provocation needs further study.

Healthy lifestyle choices could reduce the risk of stroke, dementia, and late-life depression in individuals with biologically shorter telomeres.

New research reveals that depression following stroke has a significant long-term impact on survival, recovery, and quality of life.

Find out how depression raises dementia risk throughout life – keep reading for the latest research findings.

Dementia diagnoses decline, but more Americans are living longer with the disease and need ongoing support.

Major study finds no early clinical differences between autistic boys and girls at the time of first diagnosis.

Experimental drug jacifusen shows promise for rare ALS, with some patients experiencing unprecedented recovery and stabilisation.

The study found no significant link between the presence of acute infarction and fatigue.

Long-term consumption of ultraprocessed foods is associated with an increased risk of multiple nonmotor symptoms that often precede a Parkinson’s disease diagnosis.

Aspirin cessation fails to cut cSDH recurrence post-surgery, trial reveals.

Baseline brain circuit activity predicts who benefits most from MDMA, paving the way for personalised psychiatric treatments.

Find out how maternal hypertension affects preterm infant brain development and why early intervention is crucial – read more.

Discover how psilocybin therapy could transform Parkinson’s care – read more about this promising pilot trial and future directions.

Autologous haematopoietic stem cell transplantation outperforms alemtuzumab and ocrelizumab in relapse prevention for relapsing MS.

Tricyclic antidepressants and non-invasive neuromodulation techniques lead updated neuropathic pain treatment guidelines.

Alzheimer’s risk factors impact cognition as early as age 24, study reveals.

Young adults face a low but notable risk of epilepsy after stroke, with risk factors well-predicted by current scores.

Blood pressure control over 48 months cuts dementia risk by 15% in a large clinical trial.

Research reveals that APOE4 and early dementia elevate late-onset epilepsy risk in cognitive decline.

Uncinate fasciculus lesion burden is tied to severe anxiety in MS patients, study reveals.

New study reveals specific oral microbes linked to higher pain scores in women with central sensitisation disorders.

New research shows that opioid-exposed newborns have 5% smaller brain volumes, varying by drug type.

Cognitive phenotyping boosts the accuracy of blood biomarkers in predicting brain amyloidosis in Alzheimer’s diagnosis.

A randomised clinical trial shows that the SMART-CP boosts rehab access for Bangladeshi children with cerebral palsy.

ADHD may increase risk of dementia due to elevated brain iron and neuroaxonal damage in adults.