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Keep up to date with the genomic profiling in precision oncology
April 2025
This series of educational webinars covers the latest developments in the precision medicine landscape in non-small cell lung cancer…
Read more
10 Jul 2015
STRIDE: Phase 2 study of sipuleucel-T in metastatic castration-resistant prostate cancer
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Neal Shore, MD, FACS, of Atlantic Urology Clinics, Myrtle Beach, SC, discusses…
10 Jul 2015
Julie M. Vose, MD, MBA, FASCO, elected ASCO President for 2015–2016 term
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, elected ASCO President for the 2015–2016 term, Julie M. Vose, MD, MBA, of the…
10 Jul 2015
Towards targeted therapy of chronic lymphocytic leukaemia
Jacqueline Barrientos, MD, of North Shore-LIJ Cancer Institute, Lake Success, NY, summarises recent progress in the treatment of chronic lymphocytic…
10 Jul 2015
Melanoma treatment update at ASCO 2015
Axel Hauschild, MD, of University of Schleswig-Holstein, Kiel, Germany, reviews the clinical trial data for new treatments in melanoma presented at the…
10 Jul 2015
CheckMate 067: Phase 3 trial of nivolumab in melanoma
University of Nebraska Medical Center, Omaha, NE, discusses the phase 3 CheckMate 067 trial of nivolumab alone or combined with ipilimumab versus…
10 Jul 2015
COMBI-d: Phase 3 trial of dabrafenib plus trametinib in BRAF V600E/K-mutated melanoma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Georgina Long, BSc, PhD, MBBS, FRACP, of the University of Sydney, Sydney…
10 Jul 2015
Phase 3 trial of whole brain radiation therapy in addition to radiosurgery for brain metastases
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Andrew B. Lassman, MD, of Columbia University Medical Center, New York, NY…
10 Jul 2015
The treatment landscape of metastatic kidney cancer
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, James Larkin, FRCP, PhD, of The Royal Marsden, London, UK, provides an overview…
10 Jul 2015
Phase 3 trial of eribulin versus dacarbazine in leiomyosarcoma and liposarcoma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Patrick Schöffski, MD, of University Hospitals Leuven, Leuven, Belgium…
10 Jul 2015
Phase 2 trial of lenvatinib and everolimus in metastatic renal cell carcinoma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, James Larkin, FRCP, PhD, of The Royal Marsden, London, UK, discusses the results…
10 Jul 2015
TATTON: Phase 1b trial of combination therapies with AZD9291 in EGFR-mutant lung cancer
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Geoffrey R. Oxnard, MD, of Dana-Farber Cancer Institute, Boston, MA, discusses…
26 Jun 2015
Follow up of the phase 3 RESPONSE trial of ruxolitinib in polycythemia vera
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Jean-Jacques Kiladjian, MD, PhD, of Saint-Louis Hospital & Université Paris…
26 Jun 2015
Phase 2 MMY2002 trial of daratumumab in myeloma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, María-Victoria Mateos, MD, PhD, of the University Hospital of Salamanca…
26 Jun 2015
Results of the phase 3 ELOQUENT-2 trial
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Sagar Lonial, MD, of the Winship Cancer Institute, Emory University, Atlanta, GA…
26 Jun 2015
Results of the phase 3 PERSIST-1 trial of pacritinib for myelofibrosis
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Jean-Jacques Kiladjian, MD, PhD, of Saint-Louis Hospital & Université Paris…
26 Jun 2015
Results of the phase 2 54767414MMY2002 (Sirius) trial of daratumumab for multiple myeloma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Joseph R. Mikhael, MD, of Mayo Clinic, Scottsdale, AZ, discusses the results of…
26 Jun 2015
DNMT3A R882 mutations in AML promote chemoresistance and therapeutic relapse
Multivariate analysis of patients with acute myeloid leukaemia (AML) at day 28 in clinical or pathologic complete remission showed that DNMT3A R882…
26 Jun 2015
Updated results from the SORAML trial of sorafenib in younger patients with newly diagnosed AML
The randomised, controlled phase 2 SORAML trial showed that the addition of the tyrosine kinase inhibitor, sorafenib, to chemotherapy improved event-free…
26 Jun 2015
Phase 3 CheckMate 067 trial of nivolumab in previously untreated advanced melanoma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, James Larkin, FRCP, PhD, Consultant Medical Oncologist at The Royal Marsden…
26 Jun 2015
Whole Brain Radiation Therapy is More Harmful Than Beneficial for Small Brain Metastases
In the phase 3 NCCTG N0574 (Alliance) trial, patients with 1 to 3 small brain metastases were randomised to receive stereotactic radiosurgery (SRS) alone…
26 Jun 2015
Elective Neck Dissection Improved Survival in Early Node-Negative Oral Cancer
A phase 3, randomised controlled trial showed that elective neck dissection improved overall survival by 12.5% and reduced risk of death by 36% when…
26 Jun 2015
Improved Cancer Treatments Linked to Reduced Late Mortality in Childhood Cancer Survivors
Data from the Childhood Cancer Survivor Study (CCSS), a retrospective cohort study of children diagnosed with cancer from 1970–1999 at 31 participating…
26 Jun 2015
Combined Nivolumab and Ipilimumab or Monotherapy Shown Promise in Untreated Melanoma
The randomised, double-blind, phase 3 CheckMate 067 trial showed that nivolumab alone or nivolumab plus ipilimumab significantly improved progression…
26 Jun 2015
Novel JAK Inhibitor Pacritinib Proves Effective for Easing Symptoms of Myelofibrosis
Findings from the PERSIST-1 study of patients with myelofibrosis suggest that pacritinib is significantly more effective than best available therapy…
26 Jun 2015
Obinutuzumab Doubles Remission Duration in Relapsed, Indolent Non-Hodgkin Lymphoma
Interim analysis of a phase III study finds that adding the new anti-CD20 monoclonal antibody obinutuzumab to standard bendamustine chemotherapy…
26 Jun 2015
Daratumumab Shows Promise in Heavily Treatment-Resistant Multiple Myeloma
A phase II trial suggests that anti-CD38 antibody daratumumab is effective as a standalone therapy for heavily treated multiple myeloma. In a group of…
26 Jun 2015
New Ibrutinib Combination Regimen Shows Substantial Benefits in Relapsed CLL
An interim analysis of a large phase III study suggests that the combination of ibrutinib and bendamustine/rituximab (BR) improves outcomes for patients…
2 Jun 2015
Genomic Marker Predicts Anti-PD-1 Response in Several Cancers
A phase II study identified the first genomic marker – mismatch repair (MMR) deficiency – to predict response to the anti-PD-1 antibody pembrolizumab…
2 Jun 2015
Nivolumab Extends Survival for Patients With the Most Common Lung Cancer
Findings from a randomised phase III study indicate that PD-1 immunotherapy is an effective treatment option for patients with non-squamous, non-small…
2 Jun 2015
An introduction to ASCO 2015 by the 2014-15 president, Peter Paul Yu, MD, FACP, FASCO
Peter Paul Yu, MD, FACP, FASCO introduces ASCO 2015 and the conference themes – how to utilise data, to transform it into learning to impact patient care.
21 May 2015
PARP inhibitors and the EMBRACA study of talazoparib in BRCA-related metastatic breast cancer
At the 14th St. Gallen International Breast Cancer Conference 2015, Prof. Dr. med. Peter Fasching (Friedrich-Alexander-Universität Erlangen-Nürnberg…
21 May 2015
The mechanisms of BRCA-related breast cancer and molecular profiling
At the 14th St. Gallen International Breast Cancer Conference 2015, Prof. Dr. med. Michael Untch (HELIOS Klinikum Berlin-Buch, Berlin, Germany) and Prof…
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