Oncology - European Medical Journal

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EMJ
26 Jun 2015

Improved Cancer Treatments Linked to Reduced Late Mortality in Childhood Cancer Survivors

Data from the Childhood Cancer Survivor Study (CCSS), a retrospective cohort study of children diagnosed with cancer from 1970–1999 at 31 participating…
EMJ
26 Jun 2015

Combined Nivolumab and Ipilimumab or Monotherapy Shown Promise in Untreated Melanoma

The randomised, double-blind, phase 3 CheckMate 067 trial showed that nivolumab alone or nivolumab plus ipilimumab significantly improved progression…
EMJ
26 Jun 2015

Novel JAK Inhibitor Pacritinib Proves Effective for Easing Symptoms of Myelofibrosis

Findings from the PERSIST-1 study of patients with myelofibrosis suggest that pacritinib is significantly more effective than best available therapy…
EMJ
26 Jun 2015

Obinutuzumab Doubles Remission Duration in Relapsed, Indolent Non-Hodgkin Lymphoma

Interim analysis of a phase III study finds that adding the new anti-CD20 monoclonal antibody obinutuzumab to standard bendamustine chemotherapy…
EMJ
26 Jun 2015

Daratumumab Shows Promise in Heavily Treatment-Resistant Multiple Myeloma

A phase II trial suggests that anti-CD38 antibody daratumumab is effective as a standalone therapy for heavily treated multiple myeloma. In a group of…
EMJ
26 Jun 2015

New Ibrutinib Combination Regimen Shows Substantial Benefits in Relapsed CLL

An interim analysis of a large phase III study suggests that the combination of ibrutinib and bendamustine/rituximab (BR) improves outcomes for patients…
EMJ
2 Jun 2015

Genomic Marker Predicts Anti-PD-1 Response in Several Cancers

A phase II study identified the first genomic marker – mismatch repair (MMR) deficiency – to predict response to the anti-PD-1 antibody pembrolizumab…
EMJ
2 Jun 2015

Nivolumab Extends Survival for Patients With the Most Common Lung Cancer

Findings from a randomised phase III study indicate that PD-1 immunotherapy is an effective treatment option for patients with non-squamous, non-small…
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