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Biomarker Insights in Diabetic Incontinence from New Study - EMJ

Key Biomarker Linked to Diabetic Urinary Incontinence

December 2025

A new study highlights oxidative and neuroimmune changes in diabetic urinary incontinence, identifying 4-HNE as a key biomarker differentiating diabetic and non-diabetic cases.

Inflammation Drives Chemoresistance in Bladder Cancer

Discover a study revealing how chemotherapy-induced tumour pyroptosis reprograms fibroblasts, promoting chemoresistance in bladder cancer.

Urinalysis Abnormalities Linked to Somatisation in Women Functional Dyspepsia

A new clinical study has identified a potential link between abnormal urinalysis and somatisation symptoms in female patients with epigastric pain syndrome.

Comparison of Three Post-Prostatectomy Incontinence Therapies

Pelvic floor muscle training (PFMT) is recommended as an initial treatment for post-RP SUI, but traditional home-based approaches often lack long-term adherence.

Urodynamics Offers No Added Benefit for Bladder Care

From an economic perspective, urodynamics added £463 in cost and yielded a modest 0.011 additional quality-adjusted life-years.

New Biomarkers Found in Rare Bladder Cancer Types

Discover a study that reveals a targetable CA125+ cell state in rare bladder cancer subtypes using single-cell RNA sequencing.

New Urinary Biomarkers Linked to Slower Progression of Diabetic Kidney Disease

Learn how EGF and UMOD levels may predict diabetic kidney disease progression, offering new tools for clinical risk assessment.

Targeted Therapies Improve Outcomes in Muscle-Invasive Bladder Cancer

Non-muscle invasive bladder cancer, representing roughly 75% of cases, remains confined to the bladder lining and submucosa, often recurring but rarely advancing.

Re-Irradiation Shows Promise in Local Prostate Relapse

Patients treated on the entire prostate or surgical bed had better DMFS compared to those treated only on the relapse site.

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