Abstracts

The MammaPrint® (MP) 70-gene test is utilised in personalised treatment planning for patients with early-stage breast cancer (EBC) with either node-positive or node-negative disease and categorises tumours as high risk (MP-HR; MP index: –1–≤0) or low risk (MP-LR; MP index: >0–+1).

Neuroendocrine neoplasms (NEN) represent a rare heterogeneous group with an increasing incidence, consisting of neuroendocrine tumours (NET) and neuroendocrine carcinomas (NEC), mostly prevalent in the gastrointestinal tract. Cancer stage, tumour grade, mode of treatment, and mainly early diagnosis affect overall survival rate.

Lichen sclerosus et atrophicus (LSEA) is an inflammatory skin disease that most frequently affects pre-pubertal and post-menopausal females. It commonly affects anogenital skin; however, extragenital lesions are not uncommon and occur in isolation or concomitantly with genital lesions.

The following highlights spotlight abstracts presented at the European Academy of Dermatology and Venereology (EADV) Congress 2022, specifically focusing on the latest developments in nail disorders and urticaria.

The primary endpoint analyses from the SUNSHINE and SUNRISE Phase III trials of secukinumab in moderate-to-severe hidradenitis suppurativa (HS) were featured in an oral presentation as part of the late-breaking news session at the 31st annual European Academy of Dermatology and Venereology (EADV) congress. Known collectively as the SUNNY trials, the SUNSHINE and SUNRISE studies represent the largest Phase III trials conducted in HS to date.

The authors present a study that investigated the clinical features and therapy of superior sulcus1-3 non-small cell lung cancer during a 22-year period. There was a review of 100 patients who underwent curative surgery for superior sulcus non-small cell lung cancer during a 22-year period (July 1998 to December 2020). Patients with an apical tumour and Pancoast syndrome, superior sulcus tumours with invasion of the chest wall, vertebral body, and/or subclavian arteries met the inclusion criteria.

Advances in technology in recent years increased the long-term survival rate of patients with chronic respiratory failure. As a result, the number of patients receiving long-term home mechanical ventilation (LTHV) support is increasing worldwide.1 The most important step in the management of patients with home mechanical ventilation (HMV) is to ensure adequate oxygenation and ventilation. Successful care at home requires the presence of trained caregivers and accessibility to medical devices and a care team.

Pulmonary sequelae after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from limited abnormalities to major interstitial lung diseases (ILD). Bronchoalveolar lavage (BAL) and cryobiopsy findings, integrated with the clinical and radiological scenario, may help clinicians to correctly manage patients and aid researchers in better understanding the features and pathogenic mechanisms of post-COVID-19 fibrosis.