Articles

In Part One of this narrative review examining the pathogenesis of severe coronavirus disease (COVID-19), the author addressed the mechanism by which the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus subverts the innate immune response while remaining largely invulnerable to its effector functions…

I guess there have been two significant advances in the field of device therapy while I have been practising. Firstly, the advent of complex device therapy…

Obesity is a pandemic. The prevalence of obesity (BMI >30) and morbid obesity (BMI >40) among American adults is approximately 30%…

Emerging evidence supports cardiac rehabilitation for transient ischaemic attack (TIA)/non-disabling stroke secondary prevention. This study compares…

Years after coronary artery bypass graft surgery, plaque formation or graft degeneration is a major concern. Saphenous vein grafts (SVG) are vulnerable…

Severe and fatal severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is characterised by chiefly pulmonary manifestations…

Paroxysmal nocturnal haemoglobinuria (PNH) is a rare disease of nonmalignant clonal haematopoietic stem cells with an estimated prevalence of 1–16 cases per million, which may be underestimated because of undiagnosed patients…

Type 2 diabetes mellitus is currently the main cause of chronic kidney disease, leading to end-stage renal disease in most countries around the world…