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Innovations
9 Mins
10 Jan 2019

Association of a Biomarker-Based Frailty Index with Telomere Length in Older American Adults: Findings from the National Health and Nutrition Examination Survey 1999–2002

To study the link between frailty and cellular senescence, the authors examined the association of leukocyte telomere length (LTL) with a recently…
Innovations
10 Mins
10 Jan 2019

Breaking Down Silos in Asthma Research: The Case for an Integrated Approach

The authors describe how integrative approaches may have greater power to provide a more holistic understanding of the pathophysiological mechanisms driving asthma heterogeneity…
Respiratory
7 Mins
13 Dec 2018

The Lancet Asthma Commission: Towards the Abolition of Asthma?

The more widespread use of inhaled corticosteroids (ICS) for the treatment of asthma following guideline recommendations 27 years ago1,2 delivered huge…
Hematology
10 Mins
13 Dec 2018

Editor’s Pick: Newest Approaches in Immunotherapy for Non-Hodgkin’s Lymphoma

Immunotherapy has revolutionised the treatment of haematologic malignancies. Patients with relapsed/refractory non-Hodgkin’s lymphoma have poor response…
Oncology
16 Mins
13 Dec 2018

iBiopsy® for Precision Medicine

A high-throughput artificial intelligence-powered image-based phenotyping platform, iBiopsy® (Median Technologies, Valbonne, France), which aims to…
Allergy & Immunology
8 Mins
13 Dec 2018

Liposomal-Glutathione as a Potential Therapeutic Agent to Control HIV-1 Infection and Tuberculosis

This literature review provides insights into how glutathione (GSH) plays an important role in controlling HIV-1 and Mycobacterium tuberculosis…
Nephrology
9 Mins
13 Dec 2018

From Renal Biomarkers to Therapeutic Targets: The Use of Monocyte Chemoattractant Protein 1, Transforming Growth Factor-Beta, and Connective Tissue Growth Factor in Diabetic Nephropathy and Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

In an ideal world, every condition would have a sensitive and specific marker that could be measured in a noninvasive or minimally invasive way…
Rheumatology
9 Mins
13 Dec 2018

Central Processes Underlying Fibromyalgia

Fibromyalgia is a common chronic pain disorder characterised by a robust clinical phenotype with principal features that include widespread pain and…
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