News

By mapping the interaction between TMAO and fibrinogen, the researchers were able to identify specific binding sites and structural changes that increase clot stability.

Trial finds diacerein does not improve knee pain in osteoarthritis patients with inflammation, questioning its clinical use.

Patients with rosacea may face a higher risk of depression, according to a large Korean cohort study highlighting the need for integrated care.

After 2 weeks, patients in the adjunctive FMT group demonstrated significantly greater reductions in HAMD-24 scores compared with controls (p=0.048), alongside a higher overall reduction rate (p=0.016).

Up to four in 10 cancers worldwide could be prevented, a new analysis from WHO and its International Agency for Research on Cancer has revealed.

Persistent taste dysfunction in long COVID may stem from molecular changes rather than structural damage, offering new insight into lingering symptoms.

The FIB-4 index may not reliably detect liver fibrosis in MASLD, with high false-positive and false-negative rates, highlighting challenges for primary care screening.

Discordant AI mammography results can sharply increase patient anxiety, reduce trust in radiologists, and raise second-opinion requests, but context eases concern.

Around 50% of patients with Type 2 diabetes have fatty pancreas disease, a substantial yet arguably overlooked metabolic burden.

Across the pooled analysis, tES demonstrated a significant moderate therapeutic effect in reducing OCD severity (standardised mean difference: 0.61; 95% confidence interval: 0.37–0.85; p

The Bellmunt Risk Score accurately predicts survival in metastatic castration-resistant prostate cancer, supporting its use in guiding treatment and risk stratification.

Study shows digital biomarkers from wearables can continuously track cognition and mood, enabling early detection of brain health changes.

RAAS inhibitors reduce kidney failure risk and improve blood pressure control compared with calcium channel blockers in children with CKD, new real-world data show.

Everything you need to know about meningococcal disease symptoms, prevention, and transmission, following last week’s meningitis outbreak in South East England, UK.

Study shows zoonotic viruses like SARS-CoV-2 can transmit between humans without prior adaptation, unlike lab-passaged viruses.

Researchers have identified the potential biological and psychosocial factors contributing to the bidirectional, multifactorial association between PCOS and depression.

The MEL-SELF trial reveals gaps in melanoma self-examination practices, highlighting patient confidence and psychological factors affecting early detection.

Study finds gut microbiota composition may be linked to future cardiometabolic disease and cardiovascular events in a large multi-ethnic cohort.

As of 5pm on Tuesday, 9 laboratory cases of meningitis are confirmed and 11 notifications remain under investigation by UKHSA.

Menstrual recovery after liver transplantation may indicate better graft liver health, as women whose periods returned were far less likely to develop liver complications.

Suspended lead suits dramatically reduced radiation exposure for interventional echocardiographers during left atrial appendage occlusion procedures.

In patients with post-stroke disability, all-cause mortality more than doubled (HR:2.18; 95% CI:1.84–2.60; p

Researchers reveal the anatomical sites where people with Type 2 diabetes experience a particularly higher risk of fracture.

Discrimination against NHS staff currently stands at a record high, with nearly one in 10 subjected to discrimination in the past year.

New research tracks early Parkinson’s symptoms over three years, showing how daily impacts evolve and highlighting the value of wearable monitoring.

A large retrospective study identified risk factors for CNS relapse after transplant in adults with acute lymphoblastic leukaemia, highlighting elevated risk in Philadelphia chromosome positive disease.

Two people have died amid an outbreak of meningitis and septicaemia in Kent, UK, leading the UKHSA to organise a rollout of antibiotics in the Canterbury area.

Severe COVID-19 may raise lung cancer risk by creating a tumour-promoting lung environment after viral pneumonia, new research suggests.

Virtual reality may help reduce patient anxiety, by giving people a better understanding of upcoming medical procedures, researchers reported today at EAU26.

Researchers reveal what matters most to patients with prostate cancer in treatment decisions at the Annual Congress of the European Association of Urology 2026.

With AI decision support, basic readers achieved efficiency scores comparable to expert radiologists, suggesting that AI may help standardise prostate cancer diagnosis across different levels of clinical expertise.

New research links sleep disturbances after paediatric brain injury to behavioural difficulties, suggesting sleep could be an important target for early clinical intervention.

Londoners are tuning to unsafe alternatives as NHS rollout of weight loss drugs stalls, according to a new report from the London Assembly Health Committee.

A study identifies the ribosome biogenesis factor MYBBP1A as essential for acute myeloid leukaemia cell growth, revealing a potential therapeutic vulnerability.

Analysis of patient liver biopsies and cell models suggests epigenetic silencing may limit durability of AAV gene therapy, offering insight into long term variability in haemophilia treatment.

Among the most highly prioritised features were a longer product shelf life and improved storage conditions, both receiving a median importance score of 9.

High-frequency oscillatory ventilation (HFOV) reduced bronchopulmonary dysplasia in preterm infants with neonatal respiratory distress.

EAU 2026 data show prostate cancer screening has minimal impact on men’s quality of life and health anxiety, helping fill a key evidence gap for screening policy.

South Africa is exploring local production of lenacapavir, a long-acting HIV prevention drug, to improve regional access and strengthen supply chains.

New study finds cfDNA fragmentome analysis can detect liver disease early, identify fibrosis and cirrhosis, and even predict survival across illnesses.

Researchers compared prostate and breast cancer screening outcomes in Germany in a meta-analysis presented at the Annual Congress of the European Association of Urology 2026.

Fetal cardiac imaging at 34–38 weeks identified newborns with transposition of the great arteries at high risk of severe hypoxia that would need urgent postnatal intervention.

Patients with brain metastases and Type 2 diabetes taking GLP-1RAs had a significantly lower risk of mortality over 3 years compared with nonusers in a 2026 cohort study.

This study establishes an increase in both incidence and extensiveness of newly diagnosed inflammatory bowel disease in paediatric patients over the last 40 years, and points to the necessity of further research regarding long-term outcomes.

A new AI Assistant system using smart glasses automatically tracks meals and provides personalised dietary analysis to support healthier eating behaviours.

A transcriptional classifier identifies tumour reactive T cells in multiple myeloma and predicts response to immunotherapy, offering a potential biomarker for treatment selection.

A new study identifies a paralog dependency regulating MEF2C stability in acute myeloid leukaemia and demonstrates a peptide approach that suppresses disease progression in preclinical models.

Functional experiments showed that α-zein–specific Treg cells suppressed naïve T cell proliferation when exposed to the antigen, confirming their role in maintaining oral tolerance.

Administering sucrose to newborns just before venepuncture could help relieve pain more than standard comfort measures.

Analysis revealed that a higher abundance of Eubacterium xylanophilum group spp. and Akkermansia muciniphila was associated with a lower risk of MACE+, whereas Ruminococcus gnavus group spp. was linked to higher MACE risk.

Clinical studies suggest zorevunersen could reduce seizures and improve quality of life for children and adolescents with Dravet syndrome.

Global AMR governance has improved, but antimicrobial resistance remains high, highlighting gaps in policy implementation and surveillance.

Mouse study finds impaired ammonia clearance can accelerate hepatocellular carcinoma growth and highlights potential dietary strategies to slow tumours.

Analysis of fibroid subtypes reveals unique ultrasound patterns and clinical profiles, helping differentiate usual-type from variant uterine fibroids.

Interim results from the Phase III VISIONARY trial show that sibeprenlimab significantly reduced proteinuria and improved disease biomarkers in patients with IgA nephropathy.

GLP-1RAs produce greater weight loss results among women than men, a 2026 systematic review and meta-analysis has found.

A large UK study finds commonly used eGFR equations may overestimate kidney function, potentially delaying chronic kidney disease diagnosis and treatment.

Administration of prochlorperazine or CLP-257 (or its prodrug CLP-290), significantly decreased seizure frequency in vivo, providing further evidence that enhancing KCC2 function could stabilise neuronal networks.

A study suggests convection volume in haemodiafiltration may be tailored to patient weight and residual kidney function to optimise middle-molecule clearance.

Scientists have discovered a protein, Aurora-related kinase 1, that is “indispensable” for malaria parasite survival.

Researchers use long-read genome sequencing to uncover hidden autism gene variants, improving understanding of genetic causes and advancing precision diagnostics.

A new human lung ageing atlas reveals cell-specific changes, mutation buildup, and declining lung repair capacity linked to ageing.

Last week, India and South Africa were celebrated by WHO for their progress towards the elimination of cervical cancer.

Animals receiving RIC maintained significantly better cardiac function. The intervention preserved left ventricular ejection fraction and partially prevented early structural changes in the heart.

A study of hospitalised patients with acute kidney injury shows that failing to recover creatinine within 10% of baseline at 3 months predicts worse 5-year kidney outcomes.

Taking multivitamins daily for two years can slow biological ageing, researchers reported.

Over a total number of 105,934 participants, interval cancer rates were 1.55 (95% CI: 1·23–1·92) and 1.76 (95% CI: 1·42–2·15) per 1000 participants in the intervention and control group respectively.

Machine learning reveals unique COVID vaccine immune signatures in people living with HIV, with differences in antibodies, cytokines, and T cell responses.

Post-COVID chronic liver complications, including fibrosis and cirrhosis, have been reported months after infection, highlighting long-term risks.

AI tools may help detect vertebral fractures on CT scans, matching expert accuracy and improving osteoporosis care.

In the absence of cardiomyocyte TGFB3, the study observed increased expression of profibrotic mediators including connective tissue growth factor (CTGF) and SERPINE1.

Participants with depression alone had the highest risk (HR: 1.60; 95% CI: 1.36–1.89), followed by those with both depression and VI (HR 1.56; 95% CI: 1.40–1.73).

Two-thirds of patients on GLP-1 drugs hide their treatment from loved ones, with varying stigma across social and gender differences.

A new AI model has outperformed traditional methods of bladder cancer classification, yielding a 95.5% accuracy.

A targeted social media campaign reached more than one million people eligible for lung cancer screening, highlighting digital tools for improving screening awareness.

Distinct COPD phenotypes show major differences in severity and mortality, with worse outcomes linked to income, race, rural living, and smoking.

Women with ADHD are approximately twice as likely to experience perinatal depression that those without.

Ultra-processed food consumption at 3-years-old was tied to adverse behavioural and emotional outcomes at 5-years-old in a 2026 Canadian cohort study.

Brain imaging reveals sensory amplification in chronic back pain, partially reversible with pain reprocessing therapy.

The world’s first dengue fever early warning system has been launched by researchers at the London School of Hygiene & Tropical Medicine.

Functional assays showed that PPIs also reduced fibroblast migration and oxidative stress, both of which contribute to tissue remodelling.

Pipe and cigar smoking is linked to faster lung function decline and higher mortality, even among people who have never smoked cigarettes.

The WHO has announced updated influenza vaccine strains for the 2026–27 northern hemisphere season, reflecting evolving flu virus patterns worldwide.

Multicentre study in South America suggests MASLD is a leading cause of cirrhosis, highlighting rising metabolic risk factors and gender-balanced insights.

The proportion of CT scans performed in patients aged 60–90 has risen over 10 years at a hospital, highlighting concerns about repeated radiation exposure.

The FDA has issued warning letters to 30 telehealth companies for reportedly making false claims about GLP-1 products, amid a major crackdown on pharmaceutical advertisements.

NHS England London has launched a five-year, city-wide programme to improve heart health in the capital.

Fetoscopic repair of spina bifida reduces brain edema and hindbrain bulging, but postoperative aqueductal obstruction remains a risk, study shows.

A multi-centre study shows AI-assisted CT can reduce reading time and improve consistency in tumour measurements during cancer follow-up imaging.

Individuals with higher abundance of common peanut-degrading bacteria, including Rothia, exhibited a higher threshold for allergic reactions during controlled exposure.

Researchers have expanded understanding of the pathophysiology behind reproductive mood disorders, as heard at the 2026 Annual Congress of the International Society of Gynecological Endocrinology.

The PARADIGM study will test whether artificial intelligence can match radiologists in detecting clinically significant prostate cancer on MRI across an international cohort.

Nearly 70% of the 23-year-olds binge drank at least once in the last year, with almost one in three doing so at least monthly.

ECR 2026 data show that structured reporting systems help improve radiation safety in healthcare X ray practices across Finland.

Occupational therapy interventions mitigate chemotherapy-induced cognitive impairment in women with breast cancer, showing positive trends in improving cognitive function.

New research shows why coronavirus infection may lead to long COVID, with long-term effects on the lungs and brain, unlike influenza.

Abnormal Wnt signalling may drive a rare, high-risk childhood liver cancer and influence chemotherapy response, new research suggests.

Half-dose gadopiclenol boosts breast MRI contrast while reducing gadolinium exposure, offering equivalent or better imaging than full-dose gadobutrol.

Researchers report that biomarkers such as PGRMC1 and oestrogen metabolism ratios may improve breast cancer risk screening before hormone replacement therapy, supporting more personalised clinical decisions.

Age and smoking status influence CT-based body composition in lung cancer screening, with muscle loss and fat gain increasing with age in a large NELSON cohort analysis.

New imaging research links glucose dysregulation with progression of cerebral small vessel disease, suggesting metabolic biomarkers may help identify patients at risk of worsening brain damage.

Nicotine-seeking behaviours and activity in the brain’s reward pathway have been found to be dampened through the activation of glucose-like peptide-1 receptors.

Antibiotic-treated mice demonstrated significantly smaller lesion volumes and reduced cell death compared with vehicle-treated controls after repeated injury.

Children experienced losses equivalent to 3 months of skill development in literacy and 14 months of growth in numeracy during the COVID-19 pandemic.

Adhering to Life’s Essential 8 may lower chronic respiratory disease risk and support long-term lung health, reports a large population-based study.

Denmark is validated by WHO as the first EU country to eliminate mother-to-child transmission of HIV and syphilis.

AMH may not accurately reflect ovarian reserve in women with systemic inflammation: an abstract from the 2026 Annual Congress of the International Society of Gynecological Endocrinology.

Over an approximate 4-year period, increasing sleep apnoea severity showed a clear dose–response relationship with higher PWV, independent of age, sex, and body mass index.

Low dose lithium treatment tested in mild cognitive impairment, offering effect size data for future larger trials.

Elevated levels of salience, abstinence, tolerance, craving, excessive use, desire to control consumption, and alterations in daily life habits are all tied to problematic use.

Vegetarian diets are associated with a lower risk of multiple cancers, according to the largest study to date in this field.

Novel gut health metric identifies microbial imbalance and may help detect disease progression earlier and more accurately.

Genetically higher FGF21 levels were associated with lower problematic alcohol use, fewer binge episodes, reduced weekly alcohol intake, and lower ARLD risk.

New deep learning model combining X-ray and MRI data shows promise in increasing efficiency of cervical spondylosis diagnosis.

Endothelial Twist1 expression promoted plaque growth but simultaneously enhanced hallmarks of plaque stability, including increased collagen deposition and a greater number of ACTA2-positive smooth muscle–like cells.

Sepsis may worsen or improve AKI survival depending on illness severity, new data suggest. Explore how risk reverses in the sickest patients. Read more.

A new non-peptide GLP-1 pill proved more effective for weight loss than oral semaglutide in a recent Phase III trial.

Adults with chronic headaches are nearly five times more likely to have clinical symptoms of depression, and at a more than seven times higher risk of clinical anxiety.

First-line treatments for erectile dysfunction are under-prescribed in patients with prostate cancer, despite favourable clinical outcomes.

Shared molecular changes in brain and blood may improve major depressive disorder diagnosis and guide personalised therapies.

High adherence to the Mediterranean diet was linked to a significantly lower risk of adult-onset asthma in a large Spanish cohort study.

Cervical cancer risk increases with age in women living with HIV, with a peak at 45-49-years-old.

Nearly one in four miss NHS appointments, according to a new NHS England survey of 2,000 people across the country.

LAG-3 and TIGIT expression may predict skin melanoma progression and survival. Discover how these immune markers could shape future therapies. Read more.

A large cohort study links smoking habits to Parkinson’s disease risk and all-cause mortality, showing persistent smokers have lower PD risk but quitting improves survival.

GLP-1 receptor agonists were not associated with recurrence or progression in well differentiated thyroid cancer, supporting safe clinical use.

Scientists have discovered a bacterium in Romanian cave ice that resists antibiotics used to treat infections including tuberculosis, colitis, and UTIs.

Modelling across seven African countries shows malaria in pregnancy remains a major cause of maternal anaemia, with over 2 million cases projected in 2023.

Mimio reduced total cholesterol, LDL cholesterol, LDL particle number, oxidised LDL, non-HDL cholesterol, and fasting glucose.

Obstructive sleep apnoea may affect 1 in 5 adults in the UK and USA, costing billions in lost productivity, but can be offset by effective treatment.

A temperature tested photonic crystal sensor achieves over 91% accuracy in cervical cancer screening using label free optical detection.

Study dissects HIV reservoir clones that persist on ART, revealing how CD8+ T cells and resistance pathways could be harnessed for future cure strategies.

HBV vaccination rates among infants in the USA have fallen by more than 10 percentage points in the past two years.

An estimated 72% to 94% of cases were overdiagnosed in the USA between 1991 and 2019, according to a 2026 study.

At 48 weeks, 58% of participants in the treatment group lost more than 5% of their total body weight, meeting the responder rate co-primary endpoint.

Complete response, defined as UAS7=0 at Week 12, was achieved in 22.9% of patients receiving 75 mg, 51.1% receiving 150 mg, and 37.5% receiving 300 mg.

Pre-pregnancy parental obesity is linked to nearly four times higher odds of liver disease in offspring, a 2026 cohort study has found.

SBRT was linked to lower biochemical failure and fewer acute urinary adverse events than HDR brachytherapy in intermediate-risk prostate cancer.

A pilot cluster randomised study in Ireland shows structured sensory intervention is feasible in dementia care, with strong staff engagement and device uptake.

Multi omics analysis shows ultra running drives inflammatory and oxidative red blood cell damage, impairing deformability and accelerating ageing.

Codfish oral immunotherapy improved desensitisation rates in children with fish allergy, though sustained unresponsiveness remained limited.

Rates of prescription of contraceptives are more than 30% higher in the least deprived areas of England, according to new NHS data.

The team demonstrated that CCN5 effectively inhibited doxorubicin-induced cardiac cellular senescence in both cardiac myoblasts and fibroblasts.

Most early responders with atopic dermatitis sustain minimal disease activity at one year, with baseline factors predicting long-term control.

The authors concluded that the time until onset of Alzheimer’s disease symptoms could be estimated using a single blood test within a margin of error that may be acceptable for use in clinical trials.

Researchers uncover three antimicrobial peptides in dromedary camels that show potent activity against multidrug-resistant bacteria.

A new blood test accurately identifies serious scarring in patients with liver disease, a 2026 cohort study has found.

Women experience unique changes in brain structure after a second pregnancy, MRIs revealed in a 2026 cohort study.

Altitude reduces the risk of diabetes due to red blood cells acting as the primary glucose sink during hypoxia, a 2026 study has found.

Slower gait speed is significantly associated with a higher risk of incident depression, a 2026 study has found.

The study identified 37 single nucleotide polymorphisms (SNPs) reaching suggestive significance (p

The WHO European Region is set to maintain its status as having the world’s highest tobacco use by 2030.

A new AI-powered cerebrospinal fluid liquid biopsy accurately classifies brain tumours using tiny DNA fragments, offering less invasive diagnostics.

Elevated red cell distribution width-to-platelet ratio predicts cardiac surgery-associated acute kidney injury and improves risk stratification.

Indoor asthma triggers such as smoking, poor ventilation, and mould are strongly linked to worse symptoms and daily limitations, a large study finds.

COVID-19 vaccination cuts the risk of preeclampsia in pregnant women by 33%, a 2026 prospective cohort study has found.

A UK retrospective analysis finds that baseline lung comorbidities, measured using a rheumatic disease–specific index, are linked to interstitial lung disease risk in rheumatoid arthritis.

Deep learning models, particularly a Convolutional Neural Network, demonstrated superior performance, achieving an accuracy of 99.89% in predicting cardiac arrest.

More than one in three UK adults say social media has negatively affected their mental health, amid a government scramble to tighten restrictions for children.

A new water jet surgical device combines cutting and anaesthesia, reducing tissue injury and allowing precise drug delivery.

A renewed norovirus surge is pushing hospital cases to their highest level this winter, adding strain to the NHS as winter pressures persist.

Since high levels of alanine aminotransferase are a significant biomarker of liver injury, this analysis points to the benefits of resistance exercise in patients with MASLD, which led to a noticeable decline in alanine aminotransferase levels.

Integrated PET and MRI scans can distinguish a new type of dementia, LATE, from Alzheimer’s, a 2026 observational study has found.

Mortality occurred in 4.5% of patients in the sheath group versus 18.2% in the non-sheath group. Neurological outcomes also favoured preprocedural vascular sheath insertion.

Study finds high rates of cognitive impairment in haemodialysis patients, with poorer physical function seen in those with established cognitive decline.

Metabolic and bariatric surgery offers greater cardiovascular protection than GLP-1 receptor agonists, a 2026 systematic review and meta-analysis has found.

Deep learning models have matched the diagnostic accuracy of expert endoscopists in detecting early gastric cancer.

Randomised data show leuprolide is linked to greater 12-month coronary plaque progression than relugolix in men receiving ADT for prostate cancer.

Long-term ublituximab treatment reduces relapse rates and disability progression, reinforcing early intervention strategies in multiple sclerosis care.

Macro B12 may explain persistently raised vitamin B12 levels and help avoid unnecessary bone marrow biopsy in patients with low suspicion of malignancy.

Nearly two-thirds of women stop taking prescribed antidepressants during pregnancy, a 2026 cross-sectional analysis has found.

DMT therapy significantly reduced major depressive disorder symptoms in a phase IIa trial. Learn more about this rapid-acting psychedelic approach.

Three-year BE RADIANT results highlight durable bimekizumab benefits in plaque psoriasis, improving PROs and QoL. Read more.

Heavy cannabis use linked to reduced brain activation during memory tasks, raising concerns about lasting cognitive health effects.

A European study finds hospitalisations and insufficient growth reduce health-related quality of life in childhood interstitial lung disease.

Metastatic ILC shows significant biomarker heterogeneity, limiting single biopsy reliability and highlighting challenges in detection and monitoring.

A single-dose multicomponent mRNA vaccine elicits durable immune responses against influenza and COVID-19 in a Phase 1/2 trial.

Prescribing patients with type 2 diabetes SGLT-2 inhibitors much earlier in the treatment process could prevent around 17,000 deaths in the UK, new NICE guidance suggests.

These data suggested that RIPK1 inhibition targeted two central pathological processes in inflammatory skin diseases: epidermal cell death and immune-driven inflammation. 

Colorectal cancer is now the leading cause of cancer death in men and women in the USA under the age of 50 combined, a new study by the American Cancer Society has revealed.

Higher levels of leisure-time physical activity after cancer diagnosis were associated with lower cancer mortality in survivors of several tumour types.

This study shows that brain age as a biomarker may help diagnose mental disorders earlier, and guide more personalised psychiatric treatment.

More than half of surgical ICU patients developed postoperative acute kidney injury, with sepsis, trauma, and CKD among key risk factors.

UCLA researchers use lipid nanoparticles to insert full CFTR gene into airway cells, restoring function and opening new avenues for CF therapy.

Women who have had the HPV vaccine may need fewer cervical cancer screenings, a 2026 Norwegian study has found.

Five key determinants of cardiac tamponade were highlighted: operator experience, D-dimer level, total heparin dose, AF type, and left atrial diameter.

A randomised placebo-controlled study shows silicone gel significantly improves scar quality in head and neck wounds without adverse effects.

Across 40 trials, 4 1BB based CAR T therapy targeting CD19 delivered the strongest remission rates and lower neurotoxicity in relapsed B cell precursor acute lymphoblastic leukaemia.

Breast cancer survivors with high genetic risk for excess body weight had 15% higher mortality, and required more weekly walking to mitigate inherited risk.

WHO prequalification of an additional novel oral polio vaccine boosts global outbreak response, accelerating polio eradication efforts.

A new point-of-care fingerstick test detects HBV within one hour, a 2026 diagnostic accuracy study has found.

Fused Deposition Modelling 3D printing has become a practical, accessible, and cost-effective tool in surgical settings, a 2026 systematic review has found.

Transcatheter aortic valve implantation results in a higher risk of mortality and stroke compared with surgical replacement, a 2026 systematic review has found.

GLP-1 receptor agonists were associated with lower dementia and Alzheimer’s risk in patients with type 2 diabetes and CKD stage 3 or later.

A review of 41 trials finds only two assessed dietary intake with GLP 1 receptor agonists, underscoring a critical gap in nutrition research.

Phase two data show Elenagen combined with gemcitabine significantly prolongs overall survival in platinum resistant ovarian cancer without added safety concerns.

Salvage focal therapy delivers similar 10-year survival to surgery in radiorecurrent prostate cancer, with significantly fewer perioperative complications.

Smartwatch monitoring significantly improves atrial fibrillation detection, enabling earlier diagnosis and strengthening prevention strategies in high risk patients.

Hepta refractory multiple myeloma is characterised by antigen loss, complex genomic alterations, and poor survival, with limited benefit from successive salvage therapies.

The number of women attending their first NHS mammogram has hit a 10-year high, NHS data has revealed.

Major study finds chronic exposure to wildfire smoke PM2.5 linked to 24,000 USA deaths per year, with no safe threshold and strong neurological impacts.

The WHO has highlighted a surge in maternal deaths in conflict and fragile settings, where an estimated two-thirds of all maternal deaths occur.

Study shows alcohol use disorders affects 55% of people with borderline personality disorder, highlighting urgent need for integrated clinical care.

Major depressive disorder shares a Th2 immune signature with atopic dermatitis, highlighting dupilumab as a potential targeted therapy.

New study links semaglutide to rare optic nerve damage, highlighting the need for increased awareness, monitoring, and informed prescribing.

A Phase three trial shows early immunochemotherapy significantly improves survival and enhances CD8 T cell responses in advanced non small cell lung cancer.

Releasing male Aedes aegypti mosquitoes infected with Wolbachia cut wild mosquito numbers in Singapore and lowered dengue infection risk.

A second course of R CHOP achieved durable responses in late relapse diffuse large B cell lymphoma, especially in patients relapsing more than 5 years after diagnosis.

Lung cancer in never smokers is rising, with distinct risks and biology, highlighting the need for tailored screening, prevention, and treatment.

The WHO’s new handbook offers practical guidance to strengthen STI prevention, improve care delivery, and address rising global infection rates effectively.

Large cohort study shows GLP-1 receptor agonists combined with progestins lower endometrial cancer risk and reduce hysterectomy incidence in women with benign uterine disease.

New study reveals how influenza virus infiltrates heart tissue via specialised immune cells, triggering damaging interferon responses.

A review of 22 trials finds intermittent fasting offers little to no additional weight loss benefit compared with regular dietary advice in adults with overweight or obesity.

A large prospective study in JAMA finds higher caffeinated coffee and tea intake is associated with lower dementia risk and modestly better cognitive function over decades of follow-up.

Unscheduled care attendance data provides an opportunity to identify patients at high risk of liver disease, a 2026 study has found.

AI can predict postoperative breast cancer recurrence using preoperative mammograms, a 2026 study has found.

GLP-1RAs are associated with a reduced risk of aneurysmal rupture in high-risk patient populations, a 2026 study has found.

A nationwide cohort study shows people with intellectual disabilities are less likely to participate in colorectal cancer screening and complete follow-up colonoscopy.

National data show cumulative lead exposure may triple Alzheimer’s risk and account for 18% of dementia cases annually.

A major meta-analysis of 2.8 million children identifies genetic, clinical, and early-life exposures linked to childhood food allergy risk and prevention strategies.

A global study shows obesity heightens the risk of severe infections and related deaths across multiple disease types and populations.

Endometriosis-specific MRI templates significantly improve pelvic reporting, a 2026 observational study has found.

A recent surge in the global demand for smart wearables sees an emerging body of research on the relevant health implications.

AI-enhanced stethoscope screening improves early detection of valvular heart disease, outperforming general practitioners in this study.

A long-term cohort study shows molecular diagnostics can distinguish hand eczema from psoriasis, improving treatment decisions and patient quality of life.

A neonatal warming device rapidly restores infant temperature, cuts admissions, and reduces mother-infant separation.

The risk of MASLD increases following menopause before the age of 50, according to a 2026 global cohort study.

A new AI model was able to read and diagnose brain MRI scans in seconds, researchers at the University of Michigan have found.

Tirzepatide proves superior to semaglutide in weight reduction and improving glycaemic indices, a 2026 network meta-analysis has found.

A study of 1,368 participants shows allergic rhinitis alters COVID 19 symptoms, with sublingual immunotherapy increasing respiratory risk but lowering fever incidence.

Cranberry extract supports intestinal barrier function by promoting mucin secretion, antimicrobial activity, and microbiota-driven epithelial reinforcement.

Modified water vapour thermal therapy significantly improved symptoms, urinary flow, and quality of life in men with large-volume BPH, with low complication rates.

Long-term trial data suggest speed-based cognitive training with boosters may reduce the risk of dementia diagnosis years later.

A nationwide cohort study finds higher rates of congenital malformations in babies born to mothers with chronic and end-stage kidney disease.

A new study finds adults consuming more sugary drinks have higher odds of COPD, highlighting links between diet, lung health, and overall wellbeing.

AMH and AFC levels do not independently predict embryo euploidy in patients undergoing IVF, a 2026 cohort study has found.

Quantitative coronary CT plaque measures independently predicted major adverse cardiovascular events, improving risk stratification in patients.

A multicentre trial will assess whether a nurse led self management intervention improves skills and quality of life in adults with newly diagnosed inflammatory arthritis.

Stopping washcloth use during bathing may significantly reduce chronic itch, according to a new observational dermatology study exploring simple lifestyle changes.

A UK study shows AI medical assistants perform well alone but fail to improve public health decisions in practice.

Phase 2 findings show neoadjuvant pembrolizumab produced a 71% pathological complete response rate in resectable desmoplastic melanoma, with favourable safety and three year follow up outcomes.

New algorithm maps hidden global and genetic diversity in vaginal microbiomes, offering precision tools for reproductive health research.

Combining AI-processed CECT with clinical data improves the management of unresectable hepatocellular carcinoma, a 2026 study has found.

Mammographic surveillance and adjunct imaging techniques can lower morality and enhance early detection among breast cancer survivors.

A 518 patient randomised trial shows iron bioresorbable scaffold is noninferior to a contemporary drug eluting stent at 2 years, with comparable clinical outcomes.

A global analysis of childhood CKD reveals rising adolescent incidence, widening health inequalities, and links between kidney replacement therapy access and reduced disease burden.

Maternal diabetes is associated with an increased epilepsy risk in offspring, a 2026 cohort study has found.

A clinical trial suggests intermittent fasting may reduce Crohn’s disease activity and improve symptoms, without calorie restriction.

Automated urinary incontinence screening in primary care increased diagnoses and pelvic floor therapy referrals among more than 72,000 women in a US quality-improvement study.

Researchers demonstrate that AI retinal imaging can estimate blood pressure non-invasively, potentially improving long-term hypertension assessment.

Biologically informed plasma p-tau217 cutoffs improve amyloid beta detection accuracy and cost efficiency, outperforming standard thresholds and highlighting subgroup specific strategies for clinical implementation.

New registry data show bronchiectasis affects multiple alpha-1 antitrypsin deficiency genotypes, not just Pi*ZZ, with key implications for screening.

Participants under 25-years-old had the lowest rates of menstrual awareness in both cycle and period length in a 2026 cross-sectional analysis.

The 2026 Winter Olympics is the first at which GLP-1RAs will be monitored by the World Anti-Doping Agency, amid their growing use.

A study of nearly 12,000 adults links sedentary behaviour, late sleep and psychological distress to higher adult acne risk, while regular exercise shows protective benefits.

Major trial finds immediate or high-dose TB treatment does not lower overall mortality in HIV-related sepsis, except in confirmed TB cases.

A UK trial suggests a ketogenic diet may modestly improve symptoms in treatment-resistant depression, but adherence remains a challenge.

A large US registry study found significantly worse one year cancer survival during 2020 and 2021, with an estimated 17 390 excess deaths linked to COVID-19 pandemic disruptions in care.

New research links psychotic experiences to early brain ageing, offering clues about psychosis risk in young adults.

New research identifies a tRNA-derived RNA fragment that protects skin from UV-induced photoageing by preserving collagen and stabilising key mRNAs.

Dyslexia may stem from vulnerable brain networks rather than single genes, offering new insight into diagnosis and intervention.

Quantitative digital pathology revealed distinct morphometric features among mixed odontogenic tumors, suggesting virtual cell analysis may aid diagnosis when conventional histology is inconclusive.

Rising temperatures are increasing antimicrobial resistance deaths in the Western Pacific, highlighting urgent need for global coordinated action.

New data suggest MASLD overlap alters pruritus and fatigue severity in primary sclerosing cholangitis, with implications for symptom monitoring in hepatology practice.