News

Early trial data show that olorofim may offer a valuable new option for patients with resistant invasive fungal infections.

New research at ESHRE 2025 shows a cfRNA blood test can predict preeclampsia up to five months before symptoms appear.

Although GLP-1 medicines are generally well tolerated, there have been reports of rare but serious cases of acute pancreatitis.

Even when using young donor eggs, IVF outcomes are significantly poorer in men over 45, new data from ESHRE 2025 reveal.

Find out how epinephrine administration routes impact survival in paediatric cardiac arrest—explore the latest evidence now.

CHEST guideline updates support minimally invasive resection and targeted therapy to enhance survival in Stage I–II NSCLC.

Significant regional disparities in HPV vaccine uptake threaten cervical cancer prevention goals, UKHSA warns.

Learn how prenatal tobacco alters teen brain development and behaviour, discover key findings and implications. Read more!

A groundbreaking multinational clinical trial, named RESILIENCE, is underway to test a promising new treatment aimed at preventing heart damage caused by…

Discover how climate change is profoundly altering allergic rhinitis, extending allergy seasons, and increasing healthcare burdens and educational needs globally.

Despite the well-documented association between HBV and HCC, the exact mechanisms driving HBV-induced HCC remain largely unknown.

At ESHRE 2025, researchers revealed that women with PCOS have gut and metabolic imbalances that may drive miscarriage and pregnancy complications.

Patients with functional anorectal pain show abnormal anal pressures, rectal hypersensitivity, and high rates of anxiety and depression, new study reveals.

New simulation data suggest that fatigue scores can sometimes be substituted in spondyloarthritis registries, but pain and global scores should remain distinct.

High ICU admission rates and atypical features marked France’s recent M. pneumoniae epidemic, especially in those without early macrolide therapy.

Researchers developed a self-injection assistance device, allowing patients to administer triamcinolone themselves under medical guidance.

A new study uncovers how melanomas can arise from minimal genetic changes, shedding light on the early, often elusive steps in skin cancer progression

The guidelines endorse adjuvant nivolumab for patients with pT3/4 and/or pN+ disease who are unsuitable for, or have declined, cisplatin-based chemotherapy.

Dupilumab was associated with increased lymphoma risk but lower overall mortality in a large asthma cohort study.

The study suggests that the inflammatory processes central to AR may also affect the brain, potentially leading to mood disturbances through mechanisms such as elevated cytokines or histamine imbalance.

A new clinical trial offers insight into tackling one of the biggest challenges in soft tissue sarcomas….

Biliary atresia is the most common surgical cause of cholestatic jaundice in infants and the leading reason for paediatric liver transplants

Saliva-based DNA markers could predict cancer, heart disease, and more—offering a non-invasive future for early diagnosis.

A new study highlights the clinical promise of AI-driven IHC prediction models, showing high accuracy and diagnostic concordance with conventional pathology.

A German multicentre study shows MVA-BN vaccination is safe and moderately effective in preventing mpox, especially in HIV-negative individuals.

Given dupilumab’s well-documented benefits in controlling moderate to severe AD, clinicians are advised to weigh this potential risk carefully against its therapeutic advantages.

Despite alcohol being a leading preventable cause of cancer in the United States, public awareness of its cancer risk remains strikingly low, according to a new study.

Importantly, 30% mean reductions in prostate volume were sustained up to 18 months post-procedure.

A new international trial has investigated the safety and efficacy of tailoring antibiotic treatment for cystic fibrosis exacerbations based on sputum microbiome analysis.

The combination therapy demonstrated a significantly higher response rate (98.28%) compared to loratadine alone (87.93%).

A recent prospective study explored the effectiveness of using indocyanine green to improve intraoperative detection of bile leakage.

AI now matches experts in echocardiogram interpretation, promising faster, more accessible heart diagnostics for all patients.

Delayed sputum conversion and poor outcomes are common in patients with bedaquiline-resistant TB, according to a new South African cohort study.

A large-scale study found that women with endometriosis are nearly twice as likely to be diagnosed with autoimmune diseases like lupus, rheumatoid arthritis, or Hashimoto’s within two years.

The bidirectional relationship between psoriasis and MetS was supported by evidence showing that metabolic disturbances can also exacerbate psoriasis symptoms.

Insomnia appeared in 61%, cognitive impairment and irritability in 38%, and more severe psychiatric issues such as psychosis and delirium were rarely considered.

A genome-wide association study reveals four novel loci linked to primary spontaneous pneumothorax, identifying CBX7-mediated matrix dysregulation as a key pathogenic mechanism.

Learn how CEM after DBT detects more early cancers in high-risk women, though with higher false positive rates.

Discover how zimislecel enables insulin independence in patients with Type 1 diabetes, showing strong efficacy in early clinical data.

Despite the setback, hope remains, with 138 dementia drugs currently in trials, experts say more effective, safer options may soon emerge.

Discover a study that found that individuals with higher baseline IL-1β levels experienced greater improvements in liver health following weight loss.

Blood biomarker sNfL predicts MS relapses up to a year in advance, offering new hope for earlier intervention.

Europe faces a sharp rise in hepatitis A cases, with over 2,000 infections in 2025. Vulnerable groups are most affected as ECDC urges vaccination and sanitation efforts.

Discover a study where two investigators, using new TikTok accounts registered as 13-year-olds, collected and analysed the videos through the platform’s “For You” tab.

Discover a recent study that found that smoking is associated with worse sexual function outcomes following radical prostatectomy.

AI tool GPT-4o boosts diagnosis accuracy for nerve disorders, helping non-specialists match expert recommendations in real cases.

Air pollution and poverty accelerate ageing and worsen survival in fibrotic lung disease patients, new international epigenetic study reveals.

Understand how MRI-derived RV strain predicts outcomes in HFpEF, offering improved risk stratification over traditional metrics.

Frequent nightmares accelerate ageing and triple risk of early death, highlighting a new target for preventive healthcare.

Learn how P-CAB fexuprazan matches PPI effectiveness in managing GERD-related chronic cough in an 8-week clinical trial.

In the STEP-HI randomized trial, older women recovering from hip fracture saw no added benefit in mobility from combining exercise with testosterone therapy.

Discover a new study that has assessed the relationship between indoor home environmental exposures and lung function in children with asthma.

The results suggest that while MASLD is common in patients with T2DM in primary care, advanced liver disease is rare.

A routine blood test for insulin resistance can predict which Alzheimer’s patients are at risk of rapid cognitive decline.

A long-term PsA study shows metabolic syndrome is tied to degenerative spine changes, but not joint damage, offering new insight into managing comorbidities.

Nighttime heart rate variability may reveal hidden risks for stroke, depression, and dementia, years before symptoms appear.

Children with ALL who are overweight or obese at multiple points during treatment have worse survival rates and higher relapse risk, according to a cohort study of 794 patients.

More than half of residents in European care homes experience at least one healthcare-associated infection each year, according to a major ECDC-led study.

Following surgery, 97.2% of patients experienced a reduction in psoriasis severity to mild levels or complete resolution.

Finerenone benefits heart failure patients with preserved ejection fraction, regardless of frailty, supporting its wider clinical use.

Students using ChatGPT alone scored lower than those attending lectures suggesting that AI tools may not sufficiently support complex learning.

New global registry study reveals stark regional differences in diagnosis, treatment, and care quality for children with bronchiectasis.

A new cohort study analysing over 100,000 A&E visits in North Carolina has redefined what constitutes high emergency care use among people with sickle cell disease.

THC, the main psychoactive compound, can stimulate the sympathetic nervous system, potentially causing tachycardia, vasoconstriction, and increased oxygen demand.

The findings highlight the potential for behavioural strategies, such as dietitian-led interventions, to play a key role in managing liver health.

An international study shows that many people with lupus are not physically active enough, with low activity levels linked to worse fatigue, stress, and depression.

A large-scale US study reveals that 34% of sickle cell disease patients are readmitted within 30 days of hospital discharge, nearly triple the rate of non-SCD patients.

Genetic data show that salicylic acid may alter gut microbiota and blood metabolites, raising questions about its long-term effects.

A new study found that the timing of small-bowel capsule endoscopy does not significantly affect detection rates of bleeding sources.

The findings indicate that children with HS are significantly more likely to suffer from a range of both physical and mental health conditions.

Discover a study where a checklist facilitated closed-loop management, ensuring continuity of care despite environmental changes.

Flavan-3-ols in cocoa and tea lower blood pressure and boost vascular function, supporting their use in heart disease prevention.

Discover how PSMA PET/CT before salvage radiotherapy boosts survival in prostate cancer recurrence.

Oral bacteria migrating to the gut may drive dementia risk in Parkinson’s, offering new hope for early intervention.

In a major study presented at EHA, Noella Collado-Gisbert demonstrated that residual disease kinetics are a strong predictor of survival in multiple myeloma.

Recognised with an EHA Young Abstract award, Hangjie Fu’s study reveals that ellagic acid significantly mitigates liver injury caused by iron overload.

Understand how diabetes raises risk of infection and complications post-hysterectomy.

Discover a study that found that children with early AD were more likely to develop food allergies, whereas those with later onset were more associated with allergic rhinitis.

Results showed that patients receiving the combination therapy experienced a median progression-free survival of 5.8 months, compared with 4.0 months.

Edoxaban and rivaroxaban show best balance of efficacy and safety in elderly patients with atrial fibrillation.

Eating more healthful plant-based foods may help protect eye and nerve health, new research shows, with retinal imaging revealing early signs of neuroprotection.

The Phase II CONCEPT trial has demonstrated that an isatuximab-based combination therapy achieves unprecedented rates of minimal residual disease negativity in patients with high-risk newly diagnosed multiple myeloma.

A prospective study has found that the Mediterranean diet may help reduce inflammation and support a healthier gut microbiome in newly diagnosed Crohn’s disease patients.

Azithromycin resistance in gonorrhoea has surged across Europe, underscoring the urgent need for enhanced surveillance and new treatment options.

The model integrates four key types of imagery: total-body photographs, standard clinical photos, dermoscopic close-ups, and dermatopathology slides.

Patients with atrial fibrillation now live longer after stroke, heart failure, or myocardial infarction, but bleeding risks remain unchanged.

A large meta-analysis suggests TMS improves clinical outcomes in OCD and nicotine dependence, but the role of symptom provocation needs further study.

Discover a study where researchers introduced a conceptual design for a toilet-mounted home device capable of non-invasively measuring urine flow, volume, and frequency.

New research links TP53, BRCA2, and ALKBH2 mutations to early-onset lung cancer in Asian women who have never smoked.

A large European analysis confirms circulating tumour cells (CTCs) as an independent prognostic biomarker in newly diagnosed multiple myeloma.

Learn how high TEWL after healing is linked to twice the risk of DFU recurrence.

Discover a study where findings suggest that previous estimates may have underrepresented the true HAE population by excluding HAE-nl-C1INH.

Understand how short-term use of elobixibat significantly boosts bowel movements in chronic constipation.

This study explored the effects of various metabolic abnormalities, such as central obesity, high blood pressure, and elevated high-sensitivity C-reactive protein (hsCRP), on liver steatosis and fibrosis.

Healthy lifestyle choices could reduce the risk of stroke, dementia, and late-life depression in individuals with biologically shorter telomeres.

Compared to patients from the highest SES quintile, those in the lowest quintile had over three times the odds of being diagnosed with hidradenitis suppurativa.

Early evidence shows that nirsevimab substantially reduced emergency bronchiolitis cases and hospital admissions in infants under 6 months.

A simple forecasting tool for critical care demand has been updated to better reflect changing COVID-19 pandemic conditions.

A recent study identifies the Gαi3 protein as a key factor in bladder cancer progression. Researchers found that Gαi3 promotes tumour growth and survival by activating the Akt-mTOR pathway.

Measuring coronary inflammation using CT imaging may significantly improve long-term risk assessment following percutaneous coronary intervention.

New research reveals that depression following stroke has a significant long-term impact on survival, recovery, and quality of life.

Understand how POCUS highly accurate for hip effusion diagnosis in children, when performed by trained emergency physicians.

A study has revealed that children with atopic asthma may be at greater risk of sensory processing disorder, suggesting a deeper neurodevelopmental link.

Researchers have developed an AI system that significantly increases detection of thoracic aortic aneurysms during routine breast MRIs.

Discover more about strong evidence that public health measures, such as raising alcohol prices and restricting access can significantly reduce alcohol consumption.

Understand how IVI guidance reduces PCI complications in complex coronary lesions, outperforming angiography alone.

A new EULAR 2025 study has redefined Behçet’s syndrome subtypes using latent class analysis, revealing five unique phenotypes that may inform personalized treatment strategies.

Researchers have developed an AI-based multimodal fusion system that combines CT imaging and clinical data to predict survival in patients with unresectable hepatocellular carcinoma.

Symptoms experienced over the past week were common and impactful, with over half of the participants reporting dysphagia and nearly half experiencing heartburn.

These findings suggest that most children can maintain tolerance to nuts even after a short period without exposure, following a structured course of N-OIT.

A novel blood-based assay could transform coeliac disease diagnosis, particularly for patients already on a gluten-free diet.

A new study from EULAR 2025 shows that patients with very early systemic sclerosis have a distinct pro-inflammatory fibroblast profile before any signs of fibrosis appear.

Conducted across 19 countries, this large-scale observational study gathered data from 1,392 patients with CSU and 1,374 healthy controls.

A large Phase III trial has found that onradivir, a novel PB2 polymerase inhibitor, significantly shortens recovery time in adults with uncomplicated influenza A.

High-resolution ultrasound improves diagnosis of tendon and nerve injuries in forearm lacerations, supporting better trauma care outcomes.

Dapagliflozin shows promise for treating MASH, improving liver outcomes without worsening fibrosis in a major trial.

A 2023 global call to action by over 300 experts highlighted the need for clear, cross-specialty care pathways to support earlier identification and referral of people at risk.

A new analysis from the MONITOR-PsA study, presented at EULAR 2025, demonstrates that a pragmatic treat-to-target (T2T) approach in psoriatic arthritis leads to promising clinical outcomes over 48 weeks.

New findings identify distinct symptom clusters in young children with long COVID that differ from those observed in older children and adults.

A new study finds some non-alcoholic beers raise blood sugar and triglycerides, but pilsener appears metabolically safer.