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In a direct comparison, the AI models outperformed 24 clinicians when diagnosing a subset of patients.

Pregnant women living with HIV face a global tuberculosis incidence rate almost six times that of their non-pregnant HIV-negative counterparts, research has revealed.

Each doubling of sNfL concentration increased the risk of major vascular events by 35% (adjusted hazard ratio: 1.35; 95% CI: 1.22–1.50; p

A European study shows photopatch testing with longer occlusion improves detection of sunscreen and NSAID photoallergies.

This long-term study links mentally active sedentary behaviour to reduced dementia risk compared with passive activities in middle aged adults.

London measles outbreak prompts calls for stronger vaccination efforts, with low uptake and inequalities driving rising case numbers.

Telemedicine nutrition care reduces MASLD and liver disease risk in adults with type 2 diabetes and obesity, showing promise for lifestyle-first interventions.

New vessel wall MRI detects more supracardiac atherosclerosis plaques than CTA, improving stroke evaluation and identifying embolic sources.

A single administration of SEAD1 into the prefrontal cortex restored disrupted E/I balance and improved synaptic function.

AI can distinguish children with autism spectrum disorder using eye-tracking technology with an accuracy of 85%, a 2026 systematic review has found.

Semaglutide is set to be offered to more than one million people with cardiovascular disease on the NHS in coming months.

Urinary metabolites may help detect bladder cancer and predict recurrence, offering a potential non-invasive tool to improve patient monitoring and outcomes.

Cluster trial shows TENS improves fibromyalgia pain with meaningful reductions sustained over six months and high patient satisfaction rates.

Stopping RAS inhibitors after an eGFR decline may increase risk of kidney failure and death, according to a large cohort study.

Rapid testing identifies acute respiratory distress syndrome subtypes linked to mortality, supporting precision medicine in critical care.

Topical application of 4.0% chlorhexidine to the umbilical cord may reduce neonatal mortality in low- and middle-income countries, a 2026 review has found.

The model identified approximately 13% of high-risk individuals who would not have been detected using polygenic risk scores alone.

Meta-analysis shows AI-assisted melanoma diagnosis performs similarly to dermatologists, though further validation is needed for routine clinical use.

A single cycle of psychedelic-assisted psychotherapy has been shown to substantially reduce symptoms of depression and anxiety.

Study finds higher antimicrobial resistance genes in lung disease patients, with antibiotic use linked to increased resistance in airway microbiomes.

In a northern Mexico cohort, MASLD now accounts for the largest share of chronic liver disease and cirrhosis cases.

Targeted MRI accurately assesses new bone pain in stable multiple myeloma, guiding management and reducing unnecessary whole-body scans.

Notably, the HFpEF prevalence in this INOCA group reached 35.29%, meaning over one-third of patients met established diagnostic criteria.

Novel urinary biomarkers could improve CKD risk stratification by capturing tubular injury and repair beyond traditional albuminuria measures.

Severe infections are linked to a higher dementia risk: researchers found that people with cystitis have a more than 20% increased risk.

WHO has recommended that generative AI use must be recognised as a public mental health concern, flagging concern over its growing use for emotional support among young people.

Apixaban significantly reduces bleeding risk compared with rivaroxaban in acute venous thromboembolism, based on data from a large international randomised trial.

Type D personality was linked to lower adherence and more side-effects in bilevel positive airway pressure therapy for sleep apnoea patients.

War-related disruptions to major global transport routes in the Middle East are delaying the delivery of lifesaving reproductive health supplies.

A real-world study shows delgocitinib matches PUVA effectiveness in chronic hand eczema, with trends toward improved quality of life.

Italian health authorities have been alerted of the first human case of avian influenza A(H9N2) in the EU, identified in the Lombardy Region.

An emerging and “highly divergent” SARS-CoV-2 variant has now been reported in 23 countries since first detection in November 2024, CDC reported this month.

A six factor prognostic score predicts survival in CML blast phase, enabling improved risk stratification and comparison across clinical studies.

In a mouse model of allergic rhinitis, even a very low dose (0.5 ng) of bryo-1 delivered via anionic LNPs increased antigen-specific IgA levels in salivary secretions.

Study finds indoor air pollution peaks in respiratory patients are driven by daily activities like cooking, often exceeding WHO guidelines.

Greater fitness and healthier body composition are linked to improved chemotherapy tolerance in breast cancer, with limited impact on treatment response.

WHO recommends new tuberculosis testing tools, including near point-of-care tests, tongue swabs, and sputum pooling to improve diagnosis and access.

Normothermic machine perfusion allows clinicians to assess high-risk livers from donors after circulatory or brain death before transplantation.

Synthetic radiographs are often hard to distinguish from real X-rays, challenging radiologists and AI while offering training and research opportunities.

Children with metabolically healthy obesity still face increased cardiometabolic risks by adulthood, highlighting the need for early intervention.

A classifier trained on pre-diagnostic activity and heart rate metrics demonstrated strong discriminatory ability, distinguishing patients with IPAH from controls with a ROC AUC of 0.87.

A real-world study shows transperineal prostate biopsy matches cancer detection rates while reducing infection risk compared to transrectal biopsy.

Physicians specialising in sickle cell disease report higher burnout, driven by reduced recreation and job satisfaction despite similar resilience levels.

While treatment costs were higher – A$3956 for PPOIT and A$3582 for OIT versus A$249 for no treatment – these were offset by improved clinical outcomes.

Ultra-processed food intake around conception may affect fertility in men and early embryo growth in women, according to new research.

The findings showed that videos produced by non-healthcare creators consistently achieved significantly greater numbers of reshares (p=0.0050), favourites (p=0.0495), and overall engagement rates (p=0.0014).

Longer antibiotic courses for acne raise recurrence and resistance risk without improving short-term outcomes, new real-world data show.

Large UK Biobank study links depression and gut issues to progressive supranuclear palsy risk up to a decade before diagnosis.

AI driven MRI analysis improves detection of clinically significant prostate cancer, offering higher diagnostic accuracy than traditional approaches.

Scientists have discovered a previously unknown neural pathway behind the antidiabetic effects of metformin, a standard first-line treatment for Type 2 diabetes.

Sudan faces an outbreak of acute hepatitis among displaced populations, with severe liver complications in vulnerable communities.

IVUS guidance reduces costs and rehospitalisations in lower limb venous stenting, with mixed effects for thrombectomy and thrombolysis procedures.

Discontinuation of, or interruptions to, GLP-1 treatment may increase the risk of major adverse cardiovascular events in adults with Type 2 diabetes.

Autoantibody expression after paediatric stem cell transplantation reflects immune reconstitution rather than chronic graft versus host disease risk, highlighting alternative biomarkers.

Athletes with greater BBB disruption showed worse cognitive performance compared with those with less leakage and with control participants.

A machine learning approach reveals structural HLA biomarkers linked to graft failure, offering a new strategy for donor selection in transplantation.

PSA levels fall rapidly after surgery for benign prostate enlargement, with most patients reaching normal levels within 12 weeks, new research shows.

A smart wound dressing delivers antibiotics on demand, accelerating healing while reducing antimicrobial resistance in early models.

Resident doctors in England have announced six days of industrial action following a break down of negotiations with the government over pay erosion and job shortages.

A new study identifies key predictors of successful renal replacement therapy weaning and introduces a bedside tool to guide ICU decision-making.

Large study shows reducing dampness through home upgrades improves respiratory health, especially in children, supporting housing as a key public health intervention.

HPV self-testing has proved superior to usual care in increasing cervical cancer screening rates in New Zealand, showing promise for marginalised and underscreened populations.

The analysis showed that patients with greater depression severity consistently had higher FRS values, indicating increased cardiovascular risk.

CD45RA depleted memory T cell therapy shows encouraging results in treating infections after transplant, with high survival and viral clearance rates in early findings.

Survey data reveal strong support for gene therapy in sickle cell disease, but inconsistent referral practices, limited knowledge, and insurance barriers hinder implementation.

A phase 2 trial shows promising results for hidradenitis suppurativa treatment, offering hope for patients with limited options after anti TNF therapy failure.

The International Agency for Research on Cancer has revealed the structural and social barriers stopping people from adopting cancer preventive behaviours in the EU.

Tens of thousands of people remain undiagnosed while Europe’s multidrug-resistant tuberculosis rates are up to seven times the global average.

Obesity drives liver disease progression, with new therapies and weight-loss strategies offering hope for improved outcomes in MASLD and MASH.

MULTIPLEX MRI may help identify glioma grade and molecular subtypes in a single scan, offering new insights into tumour biology.

Heart failure hospitalisation was associated with a markedly increased risk of death (adjusted hazard ratio [HR]: 6.11), far exceeding that of ACS (HR: 3.22) and major bleeding (HR: 2.62).

Trial shows clinical and molecular biomarkers can predict flare risk in rheumatoid arthritis during biologic tapering, supporting personalised treatment strategies.

Greater chronic kidney disease severity, particularly proteinuria, is linked to increased risk of cognitive impairment, a large cohort study finds.

Adults above 50 with Type 1 diabetes are nearly three times as likely to develop incident dementia as those without. Read more.

Abuse, neglect, and socioeconomic deprivation in childhood have been linked to faster ageing-related changes, including an increased risk of dementia.

Patients under active surveillance for prostate cancer with low testosterone are more likely to experience ‘extreme’ disease progression, a 2026 study has found.

Liquid biopsy significantly reduced the median turnaround time from 46.8 days to just 6.5 days, offering a substantial improvement in diagnostic efficiency.

New nomogram integrates clinical and endoscopic features to distinguish high-risk colorectal lesions from hyperplastic polyps.

New research explores COVID-19 outcomes in cystic fibrosis transplant recipients, highlighting lung function as a potential factor linked to disease severity.

Scientists have developed a new blood test that accurately detects endometriosis, catching cases missed by standard imaging techniques.

An MRI-based cohort study shows HLA-B27–positive axial spondyloarthritis is linked to higher inflammation and distinct clinical features, with similar treatment use across groups.

Liposomal retinol and niacinamide improve stability, skin penetration, and anti-aging effects, offering promise for advanced skincare formulations.

Parkinson’s weight loss is increasingly recognised as a key factor in disease progression, linked to frailty, cognitive decline and reduced quality of life.

Confirmed MenB cases now stand at 29, after reaching a peak of 34 over the weekend, according to UKHSA.

Solid nodules, smoking, and male sex are linked to fast-growing lung cancers on CT, highlighting patients at higher risk of rapid progression.

The European Centre for Disease Prevention and Control has reported that the general population in the EU is at very low risk of invasive meningococcal disease.

Mechanistic studies revealed a reciprocal relationship between receptors: S1PR1 enhanced IL-13 and IL-9 production, whereas S1PR5 suppressed these cytokines.

Scientists have discovered a small molecule inhibitor that impedes the growth of triple-negative breast cancer by inhibiting enolase 1.

A cross-sectional study finds nearly 80% of women with Sjögren’s syndrome experience sexual dysfunction, underscoring the need for routine assessment and support.

Survival rates in mice increased from 0% to 62.5%, alongside marked reductions in inflammation, alveolitis, and extracellular matrix deposition.

Advanced chronic liver disease is driven by portal hypertension. Explore how beta-blockers like carvedilol may help manage risk and delay decompensation.

Young adults with rare spinal AVMs show strong recovery after targeted endovascular treatment, guided by MRI and CT imaging of the lesions.

Metformin reduces the incidence of intermediate age-related macular degeneration by nearly 40% in people with Type 2 diabetes, a 2026 study has found.

Daily intake of avocado and mango could improve cardiovascular health in adults with prediabetes, a 2026 study has found.

Surgical smoke from robot-assisted bladder cancer surgery showed no evidence of cancer cells, DNA mutations, or exosomes.

Persistent Epstein-Barr virus antibody levels may help distinguish multiple sclerosis from similar neuroinflammatory diseases.

Castellucci and colleagues identified that a primary-outcome event had occurred in 44 (3.3%) of the 1,345 patients taking apixaban, compared to 96 (7.1%) of the 1,355 in the rivaroxaban group.

Notably, children with FPIES showed reduced abundance of Bifidobacterium, a genus widely considered beneficial for gut and immune health.

Pregnant women subjected to interpersonal racial discrimination are substantially more likely to experience postpartum depression and delivery a baby with very low birth weight.

By mapping the interaction between TMAO and fibrinogen, the researchers were able to identify specific binding sites and structural changes that increase clot stability.

Trial finds diacerein does not improve knee pain in osteoarthritis patients with inflammation, questioning its clinical use.

Patients with rosacea may face a higher risk of depression, according to a large Korean cohort study highlighting the need for integrated care.

After 2 weeks, patients in the adjunctive FMT group demonstrated significantly greater reductions in HAMD-24 scores compared with controls (p=0.048), alongside a higher overall reduction rate (p=0.016).

Up to four in 10 cancers worldwide could be prevented, a new analysis from WHO and its International Agency for Research on Cancer has revealed.

Persistent taste dysfunction in long COVID may stem from molecular changes rather than structural damage, offering new insight into lingering symptoms.

The FIB-4 index may not reliably detect liver fibrosis in MASLD, with high false-positive and false-negative rates, highlighting challenges for primary care screening.

Discordant AI mammography results can sharply increase patient anxiety, reduce trust in radiologists, and raise second-opinion requests, but context eases concern.

Around 50% of patients with Type 2 diabetes have fatty pancreas disease, a substantial yet arguably overlooked metabolic burden.

Across the pooled analysis, tES demonstrated a significant moderate therapeutic effect in reducing OCD severity (standardised mean difference: 0.61; 95% confidence interval: 0.37–0.85; p

The Bellmunt Risk Score accurately predicts survival in metastatic castration-resistant prostate cancer, supporting its use in guiding treatment and risk stratification.

Study shows digital biomarkers from wearables can continuously track cognition and mood, enabling early detection of brain health changes.

RAAS inhibitors reduce kidney failure risk and improve blood pressure control compared with calcium channel blockers in children with CKD, new real-world data show.

Everything you need to know about meningococcal disease symptoms, prevention, and transmission, following last week’s meningitis outbreak in South East England, UK.

Study shows zoonotic viruses like SARS-CoV-2 can transmit between humans without prior adaptation, unlike lab-passaged viruses.

Researchers have identified the potential biological and psychosocial factors contributing to the bidirectional, multifactorial association between PCOS and depression.

The MEL-SELF trial reveals gaps in melanoma self-examination practices, highlighting patient confidence and psychological factors affecting early detection.

Study finds gut microbiota composition may be linked to future cardiometabolic disease and cardiovascular events in a large multi-ethnic cohort.

As of 5pm on Tuesday, 9 laboratory cases of meningitis are confirmed and 11 notifications remain under investigation by UKHSA.

Menstrual recovery after liver transplantation may indicate better graft liver health, as women whose periods returned were far less likely to develop liver complications.

Suspended lead suits dramatically reduced radiation exposure for interventional echocardiographers during left atrial appendage occlusion procedures.

In patients with post-stroke disability, all-cause mortality more than doubled (HR:2.18; 95% CI:1.84–2.60; p

Researchers reveal the anatomical sites where people with Type 2 diabetes experience a particularly higher risk of fracture.

Discrimination against NHS staff currently stands at a record high, with nearly one in 10 subjected to discrimination in the past year.

New research tracks early Parkinson’s symptoms over three years, showing how daily impacts evolve and highlighting the value of wearable monitoring.

A large retrospective study identified risk factors for CNS relapse after transplant in adults with acute lymphoblastic leukaemia, highlighting elevated risk in Philadelphia chromosome positive disease.

Two people have died amid an outbreak of meningitis and septicaemia in Kent, UK, leading the UKHSA to organise a rollout of antibiotics in the Canterbury area.

Severe COVID-19 may raise lung cancer risk by creating a tumour-promoting lung environment after viral pneumonia, new research suggests.

Virtual reality may help reduce patient anxiety, by giving people a better understanding of upcoming medical procedures, researchers reported today at EAU26.

Researchers reveal what matters most to patients with prostate cancer in treatment decisions at the Annual Congress of the European Association of Urology 2026.

With AI decision support, basic readers achieved efficiency scores comparable to expert radiologists, suggesting that AI may help standardise prostate cancer diagnosis across different levels of clinical expertise.

New research links sleep disturbances after paediatric brain injury to behavioural difficulties, suggesting sleep could be an important target for early clinical intervention.

Londoners are tuning to unsafe alternatives as NHS rollout of weight loss drugs stalls, according to a new report from the London Assembly Health Committee.

A study identifies the ribosome biogenesis factor MYBBP1A as essential for acute myeloid leukaemia cell growth, revealing a potential therapeutic vulnerability.

Analysis of patient liver biopsies and cell models suggests epigenetic silencing may limit durability of AAV gene therapy, offering insight into long term variability in haemophilia treatment.

Among the most highly prioritised features were a longer product shelf life and improved storage conditions, both receiving a median importance score of 9.

High-frequency oscillatory ventilation (HFOV) reduced bronchopulmonary dysplasia in preterm infants with neonatal respiratory distress.