Created and funded by Consilient Health. Intended for UK healthcare professionals only. Prescribing information for elmiron® (pentosan polysulfate sodium) can be found here. Elmiron® is indicated for bladder pain syndrome with glomerulations and/or Hunner’s lesions in adults with moderate to severe pain, urgency and frequency of micturition.1 Adverse event reporting information can be found at the bottom of the page.
Susannah Fraser from Bladder Health UK, talks with a patient about the impact of bladder pain syndrome on her quality of life. It was 2 years before she found a treatment that controlled the pain and gave her the freedom to leave her house and take holidays again.
EAU guidelines recommend elmiron® (pentosan polysulfate sodium) for the treatment of bladder pain syndrome. Strength of recommendation: Strong. Level of evidence: 1A.2 Please refer to the summary of product characteristics before prescribing.
Elmiron® capsules offeres patients a convenient oral administered glycosaminoglycan (GAG) mimetic.3
Response to treatment should be reassessed at 6 months and treatment should continue for as long as the response is maintained.1
The most common adverse events reported in clinical studies are headache, dizziness and gastrointestinal events.1 Please refer to the summary of product characteristics before prescribing.
Visit the Urology Academy website to hear experts views on BPS treatments targeting the GAG layer. Click here 4
| Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Consilient Health (UK) Ltd, No. 1 Church Road, Richmond upon Thames, Surrey TW9 2QE UK or [email protected] |
References
1. Consilient Health Ltd. Elmiron 100 mg hard capsules, Summary of Product Characteristics. Available at: https://www.ema.europa.eu/en/documents/product-information/elmiron-epar-product-information_en.pdf. Last accessed 19 August 2025.
2. European Association of Urology. Chronic Pelvic Pain. Available at: https://uroweb.org/guidelines/chronic-pelvic-pain. Last accessed 30 June 2025.
3. Lin L et al. Bottom-up and top-down profiling of pentosan polysulfate. Analyst. 2019;144(16):4781-6.
4. Consilient Health. Urology Academy. Available at: https://urologyacademy.co.uk/home/. Last accessed: 16 September 2025.
UK-ELM-667a | September 2025
