Hema Now: Understanding Sickle Cell Disease - European Medical Journal

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Hema Now: Understanding Sickle Cell Disease

Hematology

Hema Now

In this episode of Hema Now, Karina Yazdanbakhsh speaks about her journey into immunology, the challenges of alloimmunisation, and the evolving landscape of transfusion medicine. She also reflects on receiving the prestigious Henry M. Stratton Medal for Basic Research at ASH 2025 and what this recognition means for her work. The conversation explores key insights from ASH 2025, highlights pressing immunological issues in sickle cell disease, and looks ahead to emerging technologies shaping personalised transfusion strategies.

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Karina Yazdanbakhsh is Senior Vice President and Executive Director of the Lindsley F. Kimball Research Institute at New York Blood Center Enterprises, New York City, USA. Yazdanbakhsh earned her PhD in immunology and has built an internationally recognised career focused on red blood cell immunology, transfusion medicine, and immune complications of blood disorders, including sickle cell disease.

 

 

Timestamps 

00:00 – Introduction  

00:59 – Stratton Medal meaning 

02:19 – ASH 2025 highlights 

13:11 – Sickle cell challenges 

17:00 – Immune tolerance evolution 

18:55 – Institute research priorities 

27:20 – Novel therapeutics role 

29:04 – Early career advice 

29:43 – Emerging technologies impact 

32:30 – Three magic wishes for healthcare   

Disclaimer: The opinions expressed in this episode belong to the speakers and do not necessarily represent the opinions of EMJ. 

Disclosure: Yazdanbakhsh has declared grants/contracts and support for the present work from National Institutes of Health (NIH) and National Heart, Lung, and Blood Institute (NHLBI).

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