CEREBRAL venous sinus thrombosis (CVST), a rare but serious form of stroke primarily affecting young adults, may have lasting effects on neurological and psychiatric health. New findings highlight that while short-term outcomes are generally favorable, long-term sequelae can significantly reduce quality of life and vocational recovery.
Neurological and Cognitive After-effects
Persistent headaches were reported in up to 59% of CVST survivors, and approximately 11% developed late-onset epileptic seizures. Motor or sensory deficits and visual disturbances also persisted in a subset of patients. Cognitive assessments revealed abnormalities in 14–34% of individuals, pointing to residual deficits in attention, memory, and executive function. These cognitive issues often emerge despite the absence of overt neurological disability, underscoring the importance of comprehensive follow-up beyond initial stroke recovery.
Psychiatric and Vocational Outcomes
Post-thrombosis depression affected nearly 30% of patients, reflecting the emotional burden associated with chronic neurological symptoms. Mental health challenges, coupled with lingering headaches and cognitive impairment, contribute to reduced functional independence. Between 20% and 40% of survivors were unable to return to full-time employment, revealing a substantial gap in post-stroke rehabilitation and social reintegration.
Implications for Long-Term Care
Given the high frequency of non-motor symptoms, ongoing screening for headaches, depression, and cognitive decline is critical. Multidisciplinary follow-up that integrates neurology, psychiatry, and occupational therapy can help mitigate long-term disability and improve vocational outcomes for CVST survivors.
Reference: Budrewicz S et al. Long-term neurological and psychiatric complications and vocational outcome after cerebral venous sinus thrombosis. Neurol Neurochir Pol. 2025. doi: 10.5603/pjnns.104674
