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8 Mins
23 Jun 2020

Oral Prostacyclin Pathway Agents in Pulmonary Arterial Hypertension: An Expert Clinical Consensus

PAH is a rare, progressive disorder with a number of aetiologies. Approximately 15–60 patients per million of the global population are affected…
8 Mins
23 Jun 2020

Editor’s Pick: Bone-Related Markers of Cardiovascular Disease

Vascular calcification is an independent risk factor for cardiovascular disease (CVD). Calcium deposits in coronary arteries can weaken vasomotor…
13 Mins
23 Jun 2020

National Institute for Health and Care Excellence (NICE) Guidelines on Cannabis-Based Medicinal Products: Clinical Practice Implications for Epilepsy Management

The ‘treatment gap’ for people with epilepsy is a global health emergency; this is the number of people who need epilepsy treatment but are not…
6 Mins
23 Jun 2020

The Role of Next-Generation Sequencing and Reduced Time to Diagnosis In Haematological Diseases: Status Quo and Prospective Overview of Promising Molecular Testing Approaches

This review centres on the impact next-generation sequencing (NGS) can have on the current management of haemato-oncological diseases…
5 Mins
23 Jun 2020

A Case Report: Isolated Pontine Lesion in Hypertensive of a Pregnant Patient with Idiopathic Thrombocytopenia

Posterior reversible encephalopathy syndrome (PRES) is a clinical condition characterised by headache, visual disturbances, seizures, and confusion…
5 Mins
23 Jun 2020

Mesenteric Panniculitis in a Patient with Homozygous Factor V Leiden Gene Mutation: A Case and Literature to Review

Mesenteric panniculitis was first introduced by Jura in 1924,1 who termed it retractile mesenteritis. Since then, it has also been called sclerosing…
9 Mins
23 Jun 2020

Breast Cancer Immunotherapy: From Biology to Current Clinical Applications

The complexity behind the treatment of breast cancer arises, in part, from the presence of biologically distinct subtypes…
10 Mins
23 Jun 2020

Managing Pemphigoid Gestationis

Pemphigoid gestationis (PG) is a rare pruritic autoimmune blistering skin disease associated with pregnancy and is classified as a pregnancy-specific…
4 Mins
22 Jun 2020

Pulmonary Lipoma in an Atypical Location of the Pulmonary Fissure, Extirpated by Uniportal VATS – Case Report and Review of Literature

Lipomas are the most common benign tumour in adults and can manifest in all parts of the body. Although they are of high frequency, intrathoracic…
2 Mins
15 Jun 2020

Safety and Efficacy of Mavacamten in Patients with Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy: The MAVERICK-HCM Study

Hypertrophic cardiomyopathy (HCM) is a progressive primary myocardial disorder characterised by unexplained left ventricular…
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