European Archives - Page 792 of 1115 - European Medical Journal

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17 Jul 2018

Epigenetic Dysregulation of Naïve CD4+ T Cell Activation Genes in Childhood Food Allergy

Food allergy poses a significant clinical and public health burden, affecting 2–10% of infants, and T cell dysfunction has been previously reported in…
9 Mins
17 Jul 2018

Allergoids: Ready for the Future

Improving therapy for people with allergies is a continuously evolving area and, due to the increasing prevalence of allergic diseases, options such as…
2 Mins
17 Jul 2018

Evaluation of a Treatment Scheme with the Recombinant Grass Pollen Allergy Vaccine BM32: Yielding High Allergen-Specific Immunoglobulin G Responses Associated with Clinical Efficacy

This European Academy of Allergy and Clinical Immunology (EAACI) presentation discussed the clinical development programme of a new B cell epitope-based…
9 Mins
17 Jul 2018

Towards Optimised Management of Cow’s Milk Protein Allergy

This symposium took place during the 2018 meeting of the European Academy of Allergy and Clinical Immunology (EAACI). Focussing on the fundamental…
2 Mins
17 Jul 2018

Microcrystalline Tyrosine: An Appropriate Alternative to Aluminium as Adjuvant in Vaccines and Allergen Immunotherapy

Adjuvants are compounds added to antigens in vaccines to increase the body’s immune response to an antigen.1 Similarly, adjuvants are added to allergens…
8 Mins
17 Jul 2018

Raising the Clinical Bar Beyond Current Biologics in Uncontrolled Persistent Asthma: Translating Emerging Data in Future Clinical Decisions

Asthma is a heterogeneous disease with multiple phenotypes, caused by a complex interplay of inflammatory pathways. Up to 70% of patients with asthma…
1 Mins
17 Jul 2018

Allergy Prevention by Allergens Depends on Their Ligands

The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…
8 Mins
17 Jul 2018

Editor’s Pick: Asthma and Food Allergies

There is a long-established link between allergic diseases in atopic individuals, whereby having one atopic condition can predispose that individual to…
1 Mins
17 Jul 2018

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?

Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…
9 Mins
17 Jul 2018

The Oligosaccharide Galactose-α-1,3-Galactose and the α-Gal Syndrome: Insights from an Epitope that is Causal in Immunoglobulin E-Mediated Immediate and Delayed Anaphylaxis

Galactose-α-1,3-galactose (α-Gal) is an oligosaccharide that was first described as a cause of immunoglobulin E-mediated anaphylaxis in cases of…
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