The current ‘state-of-the-art’ molecular techniques are extremely sensitive and consequently prone to false results. Even more so than in the past…

Stunted cellular immune response against a narrow range of epitopes is the hallmark of chronic hepatitis C infection, but the underneath molecular…

Hepatitis B virus (HBV)-related liver disease is a common indication for liver transplantation (LT) in Asian countries. When left untreated, the overall…

Pegylated interferon (Peg-IFN) may achieve a sustained off-treatment response in 20-30% of the patients with chronic hepatitis B (CHB).

The Z variant (Glu342Lys) of α1-antitrypsin polymerises and accumulates in the hepatocyte endoplasmic reticulum predisposing to neonatal hepatitis…

Acute-on-chronic liver failure (ACLF), a clinical syndrome associated with a dismal prognosis, occurs acutely in previously stable cirrhotic patients.

Adrenal dysfunction or insufficiency (AI) in cirrhosis, also described as hepato-adrenal syndrome, is an only recently recognised entity.

The most recent understanding of the pathogenesis of hepatic encephalopathy (HE) is that heterogeneous precipitating factors cause a low-grade cerebral…