The excessively widespread use of antibiotics has created many threats. A well-known problem is the increasing bacterial resistance to antibiotics…

Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the…

Hilar cholangiocarcinoma (HCCA) is characterised by late clinical symptoms. As a consequence, most patients will not undergo surgery, and palliation is…

Necrotising pancreatitis can be life-threatening, but the introduction of endoscopic necrosectomy has led to a tremendous reduction of lethality.

The vagus nerve, the major nerve of the parasympathetic nervous system, innervates several organs from the neck to the abdomen. The vagal branches…

Crohn’s disease is a chronic relapsing inflammatory bowel disease that may affect any part of the gastrointestinal tract. The ileum, colon, and perineum…

Several molecular mechanisms are involved in melanoma genesis and progression. Molecular targets for effective therapeutic intervention have been…

In recent decades, new chemotherapeutic agents have been introduced in cancer therapy. The skin is often the target for their toxicity.

Nails are elements of skin that can often be omitted from the dermatological assessment of leprosy. However, there are common nail conditions that…