EMJ Diabetes 9 [Supplement 1] . 2021

At the American Diabetes Association’s (ADA) virtual 81st Scientific Session, a symposium was presented wherein Ian J. Neeland, Cleveland, Ohio, USA, discussed the role of intra-organ fat in obesity pathogenesis and Roy Taylor, Newcastle upon Tyne, UK, highlighted how analysis of intra-hepatic and intra-pancreatic fat using MRI can lead to insights into practical therapy for achieving effective weight loss and remission of type 2 diabetes. This article reviews their findings and how weight loss interventions may not only help reduce cardiovascular and metabolic disease risk, but also reverse type 2 diabetes for some patients.