Bradykinin-Mediated Angioedema: Pathways, Physiology, and Disease Mechanism - European Medical Journal

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Bradykinin-Mediated Angioedema: Pathways, Physiology, and Disease Mechanism

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The publication of this infographic was funded by Pharvaris, and is based on a Pharvaris-sponsored symposium which took place on the 29th May 2025 in Budapest, Hungary.


This infographic provides an overview of bradykinin-mediated angioedema (AE-BK), including the biological pathways involved in bradykinin production and the role of the bradykinin B2 receptor. It summarises current scientific understanding of AE-BK pathophysiology, challenges in differential diagnosis, and ongoing research into potential therapeutic targets such as B2 receptor antagonism.

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