Role of Coagulation Factor Concentrates in the Operating Room - European Medical Journal

Role of Coagulation Factor Concentrates in the Operating Room

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*Cheng-Hock Toh,1,2 Yasir Alhamdi1

The authors have declared no conflicts of interest.

EMJ. ;1[4]:98-105. DOI/10.33590/emj/10313464.
Fibrinogen concentrate, fresh frozen plasma (FFP), prothrombin complex concentrate (PCC), coagulation monitoring, surgery

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The use of fresh frozen plasma, cryoprecipitate, and platelets has been the mainstay of approaches to correct coagulopathies that can arise in the perioperative setting. Limitations include the time delay from obtaining results of coagulation screens to the availability of thawed fresh frozen plasma and the potential of fluid overload. With advances in both global haemostatic testing and concentrates of coagulation factors, there are increasing opportunities for innovative practice. However, there remains a paucity of studies that can provide good quality, unbiased evidence. These issues are elaborated here to form the basis for future study.

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