The thalassaemias are a heterogenous group of inherited blood disorders with the commonality of impaired haemoglobin synthesis, resulting in ineffective erythropoiesis and haemolysis. These may result in the development of lifelong anaemia, comorbidities, and complications. Thalassaemias can place a large burden on patients and their quality of life, with significant demands on healthcare resources, while management of the disease can be complex.
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