Description: This video summarises the key recommendations of a new opinion paper by McKiernan JP et al. on the diagnosis and treatment of progressive familial intrahepatic cholestasis (PFIC) authored by a specialist committee of hepatologists.
- Describes a new algorithm developed by the panel of experts, which aims to standardise the diagnosis and management of children with PFIC in clinical practice.
- Reviews the latest guidance on the use of ileal bile acid transporter (IBAT) inhibitors in first-line treatment of PFIC.
- Provides insights from two of the authors, Professor Giuseppe Indolfi and Dr Palak Trivedi, on how treatment response can be used to inform management decisions, and early access to IBAT inhibitors might reduce disease impact.
McKiernan JP et al. Opinion paper on the diagnosis and treatment of progressive familial itnrahepatic cholestasis. J Hep Reports. 2023;DOI:10.1016/j.jhepr.2023.100949.
