Since the introduction of transcatheter aortic valve implantation (TAVI) 12 years ago, the treatment options for severe, symptomatic aortic valve stenosis in high-risk patients have significantly increased. Because of the growing implementation of TAVI in clinical practice, knowledge of the outstanding clinical outcome of TAVI and TAVI-related limitations is expanding. In this review, potential complications, including stroke, vascular complications, paravalvular regurgitation, and conduction disturbances, are discussed. To reduce the incidence of these limitations, new valves are being designed and clinically evaluated. The ultimate goal is to reduce potential complications and expand the use of TAVI to lower-risk patient cohorts.
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