Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review - European Medical Journal

Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review

Nephrology
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Authors:
*Cosimo Marcello Bruno,1 Gabriele Pricoco,1 Damiano Cantone,1 Elisa Marino,1 Francesca Bruno2
Disclosure:

The authors have declared no conflicts of interest.

Received:
11.03.16
Accepted:
26.05.16
Citation:
EMJ Nephrol. ;4[1]:92-97. DOI/10.33590/emjnephrol/10311174. https://doi.org/10.33590/emjnephrol/10311174.
Keywords:
Uric acid, urate transport, tubular handling, urate clearance

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

Abstract

In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and insulin-resistance on renal clearance of uric acid.

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