Positive Pressure Therapies Used in the Treatment of Postoperative Respiratory Failure – Evidence for Use and Future Directions - European Medical Journal

Positive Pressure Therapies Used in the Treatment of Postoperative Respiratory Failure – Evidence for Use and Future Directions

Download PDF
*Alastair J. Glossop,1 Paula Agostini2

AJG has received speaker fees, honoraria, and travel expenses from Armstrong Medical
UK Ltd.


The publication of this article was funded by Armstrong Medical UK Ltd. The views and opinions expressed are those of the authors and not necessarily of Armstrong Medical UK Ltd.

EMJ Respir. ;3[2]:107-113. DOI/10.33590/emjrespir/10311437. https://doi.org/10.33590/emjrespir/10311437.
Pulmonary atelectasis, postoperative complications, non-invasive ventilation, high-flow nasal cannulae (HFNC), positive expiratory pressure therapy

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.


Postoperative respiratory failure (RF) is a common problem following all types of major surgery, and which has significant implications for morbidity, mortality, and cost to healthcare systems. Although postoperative RF is usually multifactorial in origin, the development of atelectasis perioperatively is a significant contributory factor. A number of different techniques and devices that apply positive pressure to patients’ airways, in an attempt to prevent development of atelectasis and RF following surgery, have been studied in this patient group. Non-invasive ventilation (NIV) is considered the gold standard management for prevention and treatment of postoperative RF and is supported by the greatest body of evidence. However, the delivery of NIV requires provision of a critical care bed, has significant economic implications, and is associated with patient compliance issues. Other techniques, such as high-flow oxygen delivered by high-flow nasal cannulae (HFNC), show some promise and are supported by evidence for benefit in related areas, but currently lack supportive evidence in postoperative patients. Positive pressure physiotherapy techniques, such as positive expiratory pressure therapy, offer an inexpensive and accessible alternative to patients, but also currently lack supporting evidence of benefit with regard to clinical endpoints. Future research in the challenging area of postoperative RF should address the potential alternatives to NIV, including the precise role of HFNC, therapies that may be utilised outside of critical care areas, and combinations of existing therapies.

Keep your finger on the pulse

Join Now

Elevating the Quality of Healthcare Globally