Allergy & Immunology - European Medical Journal
×

Browse

3 Mins
18
Jul

Hereditary Alpha-Tryptasaemia Due to TPSAB1 Gene Duplication is Associated with Multifocal Sclerotic Bone Disease
Hereditary alpha-tryptasaemia (HAT) affects 4–6% of the population and is caused by allelic replications tandem duplications of the alpha-tryptase encoding…
3 Mins
18
Jul

IgE Signalling Repression by a Designer DNA Vaccine to Modulate Shrimp Hypersensitivity
Shellfish is one of the most common food allergens worldwide, causing frequent anaphylaxis in both paediatric and adult populations. Despite the…
2 Mins
17
Jul

Epigenetic Dysregulation of Naïve CD4+ T Cell Activation Genes in Childhood Food Allergy
Food allergy poses a significant clinical and public health burden, affecting 2–10% of infants, and T cell dysfunction has been previously reported in…
3 Mins
17
Jul

Evaluation of a Treatment Scheme with the Recombinant Grass Pollen Allergy Vaccine BM32: Yielding High Allergen-Specific Immunoglobulin G Responses Associated with Clinical Efficacy
This European Academy of Allergy and Clinical Immunology (EAACI) presentation discussed the clinical development programme of a new B cell epitope-based…
3 Mins
17
Jul

Microcrystalline Tyrosine: An Appropriate Alternative to Aluminium as Adjuvant in Vaccines and Allergen Immunotherapy
Adjuvants are compounds added to antigens in vaccines to increase the body’s immune response to an antigen.1 Similarly, adjuvants are added to allergens…
2 Mins
17
Jul

Allergy Prevention by Allergens Depends on Their Ligands
The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…
2 Mins
17
Jul

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?
Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…
2 Mins
17
Jul

Use of Breathomics in the Diagnosis of Paediatric Patients with Persistent Asthma
In paediatric asthma, symptoms tend to appear during the first 6 years of life and may be associated with different disease phenotypes and endotypes, each…