Allergy & Immunology

Abstracts

Analysis of Inflammatory Parameters During Asthma Exacerbations and Stable Asthma in Patients With Moderate-Severe Asthma

2 Mins

July 2020

Asthma exacerbations (AE) are defined as acute or subacute worsening of symptoms from the patient’s usual status and are responsible for most of the morbidity in patients with asthma.

Hereditary Alpha-Tryptasaemia Due to TPSAB1 Gene Duplication is Associated with Multifocal Sclerotic Bone Disease

Hereditary alpha-tryptasaemia (HAT) affects 4–6% of the population and is caused by allelic replications tandem duplications of the alpha-tryptase encoding…

IgE Signalling Repression by a Designer DNA Vaccine to Modulate Shrimp Hypersensitivity

Shellfish is one of the most common food allergens worldwide, causing frequent anaphylaxis in both paediatric and adult populations. Despite the…

Epigenetic Dysregulation of Naïve CD4+ T Cell Activation Genes in Childhood Food Allergy

Food allergy poses a significant clinical and public health burden, affecting 2–10% of infants, and T cell dysfunction has been previously reported in…

Evaluation of a Treatment Scheme with the Recombinant Grass Pollen Allergy Vaccine BM32: Yielding High Allergen-Specific Immunoglobulin G Responses Associated with Clinical Efficacy

This European Academy of Allergy and Clinical Immunology (EAACI) presentation discussed the clinical development programme of a new B cell epitope-based…

Microcrystalline Tyrosine: An Appropriate Alternative to Aluminium as Adjuvant in Vaccines and Allergen Immunotherapy

Adjuvants are compounds added to antigens in vaccines to increase the body’s immune response to an antigen.1 Similarly, adjuvants are added to allergens…

Allergy Prevention by Allergens Depends on Their Ligands

The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?

Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…

Use of Breathomics in the Diagnosis of Paediatric Patients with Persistent Asthma

In paediatric asthma, symptoms tend to appear during the first 6 years of life and may be associated with different disease phenotypes and endotypes, each…

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