Allergy & Immunology

Patients with elevated TSLP may represent a unique target population for specific therapies, including biologics that modulate Type 2 inflammation.

The JECS cohort followed more than 88,000 newborns across Japan, assessing allergic conditions from birth to age four.

These declines were observed regardless of atopic dermatitis diagnosis, indicating that early food introduction benefits both high-risk and general populations.

This paradoxical effect appears to be context-dependent, influenced by factors such as infection, allergen exposure, and systemic stress.

The study found that urinary øLT levels were significantly elevated, four- to five-fold higher, in patients with severe asthma compared to healthy controls.

Enhancing PPIE in allergic disease research offers tangible benefits, from improving patient outcomes to ensuring studies align with real-world needs.

The review revealed that patients consistently prioritise rapid symptom relief, preferably within two weeks, alongside long-term control of hives, itching, and swelling.

The study found that pectin treatment improved Pru p 3 tolerance in over half of participants, with 30% achieving full tolerance to the equivalent of a whole peach.