Dermatology

Sunscreen use may prevent UV-induced gene and epigenetic changes, helping maintain pathways linked to healthy skin, according to new molecular profiling research.

A phase IIb trial demonstrates that topical pumecitinib 3% gel significantly improves mild-to-moderate atopic dermatitis, with twice-daily dosing showing superior efficacy.

A cohort study shows mycophenolate mofetil and methotrexate reduce disease activity in juvenile localised scleroderma, with fewer adverse effects seen with MMF.

A 52-week study shows risankizumab improves both visible psoriasis and underlying vascular inflammation, with OCT revealing sustained subclinical skin changes.

A nationwide Dutch study reports treatment patterns, upstaging rates, and long-term recurrence outcomes in patients with lentigo maligna.

Acne risk rises sharply in transmasculine individuals starting testosterone and also affects transfeminine patients on estradiol. Read more.

Real-world data from Italy show high two-year drug survival and sustained disease control with bimekizumab in moderate-to-severe plaque psoriasis.

A birth cohort study reveals how genetics, environment, and hygiene shape the infant skin microbiome and its early links to atopic dermatitis.

Real-world registry data from Germany show apremilast improves psoriasis severity and quality of life, with a safety profile consistent with clinical trials.

Real-world data suggest lebrikizumab delivers sustained clinical and quality-of-life improvements in patients with moderate-to-severe atopic dermatitis.

Lower dietary antioxidant intake is linked to higher oxidative stress in rosacea, with potential implications for disease severity and clinical management.

Real-world Danish registry data show that biologic drug survival in psoriasis differs between biologic-naive and bioexperienced patients.

Adjunctive vitamin D may improve pain, healing, and inflammation in oral lichen planus, with benefits most evident during the first six weeks of treatment.

Spatial proteomics analysis shows tertiary lymphoid structures correlate with immunotherapy response and survival in Merkel cell carcinoma.

A large Mendelian randomisation study reveals that higher BMI and IBD causally increase hidradenitis suppurativa risk, providing actionable insights for dermatologists and patient counselling.

Adjunctive NB-UVB phototherapy improved disease control in chronic plaque psoriasis patients with secondary loss of response to adalimumab.