Dermatology

A three-year cohort study found sustained dupilumab effectiveness and safety in children with atopic dermatitis, with higher itch and quality-of-life impairment among younger children.

A population-based study found rising generalised pustular psoriasis prevalence in England, alongside increased mortality risk and reduced life expectancy.

A nationwide cohort study found rare tuberculosis and meningitis among patients receiving systemic psoriasis treatments, while IL-17 inhibitors were associated with higher candidiasis risk.

Omalizumab drug survival reached 3.1 years in chronic urticaria, with autoimmune and atopic comorbidities linked to distinct discontinuation patterns.

A phase III trial found no clinical benefit from efgartigimod plus prednisone over prednisone alone in moderate-to-severe pemphigus.

Research suggests CD1a-autoreactive T cells may sense chronic skin barrier compromise through altered sphingomyelin activity, linking lipid processing with immune activation in atopic dermatitis.

MMS showed no significant difference in five-year CSCC recurrence versus standard excision, while producing smaller surgical defects.

A Chinese multicentre cohort identified 11 causative genes and distinct genotype–phenotype patterns in non-syndromic hereditary hypotrichosis.