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Topical Pumecitinib for Mild-to-Moderate Atopic Dermatitis - EMJ

Topical JAK Inhibitor Shows Promise for Atopic Dermatitis

February 2026

A phase IIb trial demonstrates that topical pumecitinib 3% gel significantly improves mild-to-moderate atopic dermatitis, with twice-daily dosing showing superior efficacy.

Topical Pumecitinib for Mild-to-Moderate Atopic Dermatitis - EMJ

Topical JAK Inhibitor Shows Promise for Atopic Dermatitis

A phase IIb trial demonstrates that topical pumecitinib 3% gel significantly improves mild-to-moderate atopic dermatitis, with twice-daily dosing showing superior efficacy.

Juvenile Localised Scleroderma

Mycophenolate Matches Methotrexate in Juvenile Localised Scleroderma

A cohort study shows mycophenolate mofetil and methotrexate reduce disease activity in juvenile localised scleroderma, with fewer adverse effects seen with MMF.

Risankizumab Shows Long-Term Psoriasis Benefits on OCT - EMJ

Optical Coherence Therapy Reveals Subclinical Benefits of Risankizumab in Psoriasis

A 52-week study shows risankizumab improves both visible psoriasis and underlying vascular inflammation, with OCT revealing sustained subclinical skin changes.

Lentigo Maligna Treatment and Recurrence Rates - EMJ

Netherlands Data Highlight Treatment Patterns and Recurrence Risk in Lentigo Maligna

A nationwide Dutch study reports treatment patterns, upstaging rates, and long-term recurrence outcomes in patients with lentigo maligna.

Acne Risk Rises Markedly After Gender-Affirming Hormone Therapy

Acne Risk Rises Markedly After Gender-Affirming Hormone Therapy

Acne risk rises sharply in transmasculine individuals starting testosterone and also affects transfeminine patients on estradiol. Read more.

Bimelkizumab Shows Long-term Effectiveness for Psoriasis - EMJ

Evidence Supports Effectiveness of Bimekizumab in Plaque Psoriasis

Real-world data from Italy show high two-year drug survival and sustained disease control with bimekizumab in moderate-to-severe plaque psoriasis.

infant skin microbiome

Infant Skin Microbiome Associations with Early Atopic Dermatitis

A birth cohort study reveals how genetics, environment, and hygiene shape the infant skin microbiome and its early links to atopic dermatitis.

Registry Data Support Apremilast in Psoriatic Disease

Real-world registry data from Germany show apremilast improves psoriasis severity and quality of life, with a safety profile consistent with clinical trials.

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