Gastroenterology

A multicentre cohort found malnutrition was common at diagnosis of paediatric inflammatory bowel disease, while most underweight patients improved during follow up.

A multicentre study of 455 patients with IBD found that worsening illness perceptions preceded increased functional health literacy difficulties over 12 months.

Grape seed extract reduced hs-CRP in patients with ulcerative colitis, but most outcomes showed no benefit over placebo.

A pilot study found faecal microbiota transplantation was associated with mucosal E. coli decolonisation and increased mucosal microbial diversity in Crohn’s disease.

Five-year PROFILE follow-up linked early top-down therapy in Crohn’s disease with fewer surgeries, hospital admissions and stricturing or penetrating disease than step-up treatment.

A new super-resolution microscope could help scientists better understand IBD and identify potential targets for treatment.

Bulgarian children with Type 1 diabetes had higher H. pylori and CagA seropositivity than controls, prompting calls for further research.

A narrative review found that GLP-1 receptor agonists supported weight loss in patients with IBD and obesity, while longer-term clinical and endoscopic outcomes remained uncertain.