Gastroenterology

Real-world data show distinct determinants of health-related quality of life in Crohn’s disease and ulcerative colitis, highlighting phenotype-specific roles of inflammation, imaging findings, treatment burden, and modifiable risk factors.

A decade-long retrospective study shows IgG4-related cholangitis responds well to steroids, with low mortality and no progression to cholangiocarcinoma.

Integrated structural and functional MRI identifies brain-based biomarkers that distinguish active from remissive Crohn’s disease and correlate with gut inflammation.

New research shows resilience partially offsets financial toxicity and improves quality of life in patients with primary liver cancer, highlighting the importance of psychosocial support.

Colonic stent placement as a bridge to surgery shows similar survival to emergency resection while reducing stoma rates in obstructive colorectal cancer.

A randomized trial shows combined water exchange and cap-assisted colonoscopy shortens cecal intubation time and reduces pain in unsedated procedures.

A retrospective cohort study shows that gastrointestinal involvement in granulomatosis with polyangiitis is linked to higher disease activity, earlier relapse, and a threefold increase in mortality risk.

CT imaging features including appendicolith, appendiceal diameter, fat stranding, and periappendiceal air help identify patients at risk of complicated acute appendicitis.