Hematology

Early haematopoietic stem cell transplantation after liver transplantation resulted in 90% survival in children with hepatitis-associated aplastic anaemia, with normal blood counts and liver function at follow up.

Hetrombopag achieved an overall response in over three quarters of paediatric patients with immune thrombocytopenia, with durable responses and no serious adverse events reported.

RBC immunization affects over 14% of transfused patients with myelodysplastic syndromes and is independently associated with markedly reduced survival, highlighting its emerging prognostic relevance.

The ESCORT-HU and ESCORT-HU Extension studies followed 3,145 patients, with 1412 (45%) men and 1733 (55%) women….

Individuals with large spleens face increased risk of hematologic cancer and liver disease, supporting the use of spleen size thresholds in clinical assessment.

A new genetic classification integrating co-mutations significantly refines risk stratification in NPM1-mutated AML and may guide allogeneic transplant decisions in first complete remission.

An all oral iberdomide based combination achieved a median progression free survival of 17.6 months in heavily pretreated patients with relapsed and refractory multiple myeloma.