Hematology

Patients with inherited bleeding disorders remain uncertain when comparing treatment options, highlighting opportunities to strengthen shared decision making.

Reduced toxicity conditioning was associated with encouraging survival and transplant outcomes in children with X linked hyper IgM syndrome undergoing allogeneic haematopoietic cell transplantation.

Young adults with sickle cell disease who used problem focused coping strategies demonstrated higher transition readiness scores, highlighting a potential target for interventions supporting transfer to adult healthcare.

Aspirin alone matched rivaroxaban and aspirin for venous thromboembolism prevention after hip and knee arthroplasty.

A new molecular evolution framework improved prognostic accuracy in myelodysplastic syndromes and reclassified more than 40% of patients.

The MHRA has approved the use of UK-donor plasma for five high-priority plasma-derived medicinal products.

A multicentre cohort study found that pretransfusion haemoglobin and anticoagulant preservative solution were associated with outcomes after red blood cell transfusion in very low birth weight infants.

Continuous haemoglobin reference curves may improve paediatric laboratory interpretation by overcoming age partitioning and highlighting differences from current WHO thresholds.