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2 Aug 2018

Genes and Pathways Dysregulated by Nilotinib Treatment in Bone Marrow CD34+/Lin- Cells of Patients with Chronic-Phase Chronic Myeloid Leukaemia

Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder with heterogeneous biological and clinical features. Specifically, it presents a…
2 Mins
2 Aug 2018

A High Pretreatment Bone Marrow CD34+/CD38- Cell Burden in Patients with Myelodysplastic Syndrome is a Prognostic Factor for Disease Progression After Allogeneic Stem Cell Transplantation

Myelodysplastic syndromes (MDS) are highly heterogeneous clonal haematopoietic disorders. Allogeneic haematopoietic stem cell transplantation (HSCT)…
2 Mins
2 Aug 2018

Longitudinal Trend Analysis of Serum Transferrin Receptor-1 Level in a Cohort of 104 Patients Affected by Non-Transfusion-Dependent Thalassaemia

The proper management of patients with non-transfusion-dependent thalassaemia (NTDT) has been a challenging mission. In fact, NTDT encompasses a great…
1 Mins
2 Aug 2018

Combined Oral Administration of Analgesia and Anxiolysis for Pain Associated with Bone Marrow Aspiration and Biopsy

Bone marrow aspiration and biopsy (BMAB) is a painful procedure. The commonly adopted local infiltration anaesthesia (LIA) with lidocaine is unable to…
1 Mins
2 Aug 2018

Novel Agents for the Management of Relapsed Multiple Myeloma

Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. MM accounts…
2 Mins
8 Aug 2017

The Simm Study: Survey of Integrative Medicine in Myeloproliferative Neoplasms

In patients with myeloproliferative neoplasms (MPN), including essential thrombocytosis (ET), polycythaemia vera (PV), and myelofibrosis (MF), symptoms…
2 Mins
8 Aug 2017

Targeting Nanoparticles to Chronic Lymphocytic Leukaemia: Exploiting the Properties of CXCR4

A key aim of modern cancer medicine is the improvement of treatment efficacy and overall patient health using targeted therapies.
2 Mins
8 Aug 2017

Haemoglobin Level and White Cell Count in Patients Clinically Suspected to have Essential Thrombocythaemia may help in Predicting Early Primary Myelofibrosis or Unclassifiable Myeloproliferative Neoplasm

Accurate diagnosis of essential thrombocythaemia (ET) and differentiation between ET and pre-fibrotic stages of primary myelofibrosis (PMF) can be…
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