Hepatology

A large-scale study finds that the hepatitis E vaccine HEV 239 significantly reduces the risk of symptomatic hepatitis E among individuals with chronic hepatitis B.

The connection between Type 2 diabetes and NAFLD is primarily driven by insulin resistance, which increases free fatty acid levels.

Time-restricted feeding (TRF), limits food intake to a set daily window, such as the 16:8 model.

Mitochondrial impairment is a key factor in MASLD and MASH development, affecting oxidative capacity and energy homeostasis.

Overall, the global hepatitis A landscape has evolved due to shifting transmission routes and pandemic responses.

A clinical trial found that pomegranate peel extract improves liver enzymes, triglycerides, and inflammation markers in NAFLD patients.

These findings challenge existing practices in some institutions that administer prophylactic anticoagulation after liver transplantation.

The study suggests that rencofilstat 225mg/d improves both liver function and portal-systemic shunting in patients with MASH.