Interventional Cardiology

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EuroPCR 2026: TTVI Surpasses Surgery in Tricuspid Regurgitation

May 2026

Transcatheter treatment for tricuspid regurgitation increased more than tenfold in Germany between 2018–2023 and was associated with lower in-hospital mortality than surgery, according to data presented at EuroPCR 2026.

ischaemic heart disease

Poor Diet Drives Global Ischaemic Heart Disease Burden

New findings from the Global Burden of Disease 2023 analysis showed that dietary risks were responsible for an estimated 4.06 million IHD deaths and 96.84 million disability-adjusted life years in 2023.

Atrial Fibrillation Treatment: Devices vs Anticoagulants

Non–procedure-related bleeding occurred in 10.9% of patients receiving left atrial appendage closure versus 19.0% of those on anticoagulants (hazard ratio: 0.55; 95% CI: 0.45–0.67; p

HFpEF

Hidden HFpEF Prevalence Found in INOCA Patients

Notably, the HFpEF prevalence in this INOCA group reached 35.29%, meaning over one-third of patients met established diagnostic criteria.

Heart Failure Drives Mortality After PCI

Heart failure hospitalisation was associated with a markedly increased risk of death (adjusted hazard ratio [HR]: 6.11), far exceeding that of ACS (HR: 3.22) and major bleeding (HR: 2.62).

Prior Stroke Predicts Mortality After Acute Myocardial Infarction

In patients with post-stroke disability, all-cause mortality more than doubled (HR:2.18; 95% CI:1.84–2.60; p

Cardiomyocyte TGFB3 Preserves Cardiac Function in Heart Failure

Cardiomyocyte TGFB3 Preserves Cardiac Function in Heart Failure

In the absence of cardiomyocyte TGFB3, the study observed increased expression of profibrotic mediators including connective tissue growth factor (CTGF) and SERPINE1.

TWIST1-Driven Atherosclerotic Plaques Show Surprising Stability

TWIST1-Driven Atherosclerotic Plaques Show Surprising Stability

Endothelial Twist1 expression promoted plaque growth but simultaneously enhanced hallmarks of plaque stability, including increased collagen deposition and a greater number of ACTA2-positive smooth muscle–like cells.

PCI

Preprocedural Vascular Sheath Insertion Cuts PCI Mortality

Mortality occurred in 4.5% of patients in the sheath group versus 18.2% in the non-sheath group. Neurological outcomes also favoured preprocedural vascular sheath insertion.

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